PKCε is a permissive link in integrin-dependent IFN-γ signalling that facilitates JAK phosphorylation of STAT1

Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors.

1996 • 769 citations

Integrin signaling and cell growth control

1998 • 655 citations

Multiple pathways control protein kinase C phosphorylation

2000 • 598 citations

Fibrillar Collagen Inhibits Arterial Smooth Muscle Proliferation through Regulation of Cdk2 Inhibitors

1996 • 514 citations

alpha vbeta 3 integrin associates with activated insulin and PDGFbeta receptors and potentiates the biological activity of PDGF

1997 • 493 citations

PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2

1999 • 440 citations

The Pseudokinase Domain Is Required for Suppression of Basal Activity of Jak2 and Jak3 Tyrosine Kinases and for Cytokine-inducible Activation of Signal Transduction

2002 • 309 citations

Regulation of Protein Phosphatase 2A by Direct Interaction with Casein Kinase 2α

1997 • 266 citations

Mutational switch of an IL-6 response to an interferon-γ-like response

2002 • 262 citations

Protein Kinase Cϵ Is Required for Macrophage Activation and Defense Against Bacterial Infection

2001 • 241 citations

A Signaling Complex of Ca ²⁺ -Calmodulin-Dependent Protein Kinase IV and Protein Phosphatase 2A

1998 • 233 citations

Identification of Kinase-Phosphatase Signaling Modules Composed of p70 S6 Kinase-Protein Phosphatase 2A (PP2A) and p21-activated Kinase-PP2A

1999 • 201 citations

A 3-Phosphoinositide-dependent Protein Kinase-1 (PDK1) Docking Site Is Required for the Phosphorylation of Protein Kinase Cζ (PKCζ) and PKC-related Kinase 2 by PDK1

2000 • 185 citations

Mammalian TOR Controls One of Two Kinase Pathways Acting upon nPKCδ and nPKCε

1999 • 182 citations

Integrin α2β1 Promotes Activation of Protein Phosphatase 2A and Dephosphorylation of Akt and Glycogen Synthase Kinase 3β

2002 • 174 citations

PKCepsilon controls the traffic of beta1 integrins in motile cells

2002 • 156 citations

Fibroblast Quiescence in Floating or Released Collagen Matrices

2001 • 92 citations

Dynamic redistribution of STAT1 protein in IFN signaling visualized by GFP fusion proteins

1999 • 72 citations

β1-Integrin and PTEN control the phosphorylation of protein kinase C

2000 • 43 citations

Dephosphorylation of PKCδ by protein phosphatase 2Ac and its inhibition by nucleotides

2002 • 42 citations

Signalling Pathways Regulating the Dephosphorylation of Ser729 in the Hydrophobic Domain of Protein Kinase Cε upon Cell Passage

2001 • 30 citations

Protein Kinase C-α and Protein Kinase C-ε Are Required for Grb2-associated Binder-1 Tyrosine Phosphorylation in Response to Platelet-derived Growth Factor

2002 • 28 citations

Regulation of both PDK1 and the Phosphorylation of PKC-ζ and -δ by a C-Terminal PRK2 Fragment

2001 • 20 citations

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