Contribution of drug transport and reductases to daunorubicin resistance in human myelocytic cells

Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors.

1982 • 667 citations

Active efflux of daunorubicin and adriamycin in sensitive and resistant sublines of P388 leukemia.

1979 • 454 citations

Mechanisms of resistance to daunorubicin in Ehrlich ascites tumor cells.

1978 • 268 citations

Uptake and retention of adriamycin and daunorubicin by sensitive and anthracycline-resistant sublines of P388 leukemia

1978 • 212 citations

Enhancement of sensitivity to adriamycin in resistant P388 leukemia by the calmodulin inhibitor trifluoperazine.

1983 • 167 citations

Tissue distribution and disposition of daunomycin (NCS-82151) in mice: fluorometric and isotopic methods.

1970 • 146 citations

In vivo characteristics of resistance and cross-resistance of an adriamycin-resistant subline of P388 leukemia.

1978 • 135 citations

DRUG RESISTANCE AND MEMBRANE ALTERATION IN MUTANTS OF MAMMALIAN CELLS

1975 • 129 citations

Cross resistance between vinca alkaloids and anthracyclines in Ehrlich ascites tumor in vivo.

1972 • 115 citations

Correlation of double-minute chromosomes with unstable multidrug cross-resistance in uptake mutants of neuroblastoma cells.

1981 • 114 citations

Cellular resistance to daunomycin in Chinese hamster cells in vitro.

1971 • 113 citations

Daunorubicin in the therapy of acute granulocytic leukemia.

1973 • 108 citations

Drug resistance in Chinese hamster lung and mouse tumor cells.

1983 • 105 citations

Heterogeneity of anthracycline antibiotic carbonyl reductases in mammalian livers

1978 • 72 citations

Comparison and characterization of mammalian xenobiotic ketone reductases.

1979 • 63 citations

Daunomycin metabolism in rat tissue slices.

1970 • 56 citations

Enhanced efflux of actinomycin D, vincristine, and vinblastine in adriamycin-resistant subline of P388 leukemia

1979 • 56 citations

Isolation and preliminary characterization of an Adriamycin-resistant murine fibrosarcoma cell line.

1983 • 45 citations

High-dose daunorubicin therapy for acute nonlymphocytic leukemia: Correlation of response and toxicity with pharmacokinetics and intracellular daunorubicin reductase activity

1972 • 41 citations

Development of resistance to daunomycin (NSC-82151) in Ehrlich ascites tumor.

1971 • 40 citations

Uptake of adriamycin and daunomycin in L1210 and human leukemia cells: a comparative study.

1976 • 38 citations

Effects of verapamil on daunomycin cellular retention and cytotoxicity in P388 leukemic cells.

1984 • 38 citations

Development of resistance to adriamycin (NSC-123127) in Ehrlich ascites tumor in vivo.

1972 • 32 citations

Comparative uptake, metabolism and retention of anthracyclines by tumors growing in vitro and in vivo

1980 • 31 citations

Correlation of unstable multidrug cross resistance in Chinese hamster ovary cells with a homogeneously staining region on chromosome 1.

1983 • 30 citations

Evidence of altered influx of adriamycin into anthracycline-resistant cells.

1981 • 25 citations

Daunorubicin accumulation by human myeloblasts varying in anthracycline resistance

1984 • 14 citations

Uptake and metabolism of daunorubicin by human myelocytic cells

1985 • 13 citations

Daunorubicin reductase activity in human normal lymphocytes, myeloblasts and leukemic cell lines

1985 • 12 citations

Cross resistance and cellular uptake of 4′-O-methyldoxorubicin in experimental tumors with acquired resistance to doxorubicin

1981 • 10 citations

Comparative uptake, retention and cytotoxicity of daunorubicin by human myeloid cells

1986 • 9 citations

Daunorubicin reductase activity in leukemia leukocyte homogenates.

1979 • 6 citations

Correlation of Unstable Multidrug Cross Resistance in Chinese Hamster Ovary Cells with a Homogeneously Staining Region on Chromosome 1

1983 • 6 citations

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