Correlation of Unstable Multidrug Cross Resistance in Chinese Hamster Ovary Cells with a Homogeneously Staining Region on Chromosome 1

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

A RAPID BANDING TECHNIQUE FOR HUMAN CHROMOSOMES

1971 • 5,049 citations

Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells.

1978 • 972 citations

Reduced permeability in CHO cells as a mechanism of resistance to colchicine

1974 • 695 citations

Alteration of Cell-Surface Proteins by Viral Transformation and by Proteolysis

1973 • 666 citations

Improved techniques for the induction of mammalian cell hybridization by polyethylene glycol

1976 • 542 citations

Gene amplification causes overproduction of the first three enzymes of UMP synthesis in N-(phosphonacetyl)-L-aspartate-resistant hamster cells.

1979 • 484 citations

Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line.

1978 • 393 citations

Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes.

1979 • 376 citations

Molecular Actions and Targets for Cancer Chemotherapeutic Agents

1981 • 361 citations

Amplification of the metallothionein-I gene in cadmium-resistant mouse cells.

1981 • 314 citations

Double Minute Chromosomes and the Homogeneously Staining Regions in Chromosomes of a Human Neuroblastoma Cell Line

1977 • 195 citations

Methods in membrane biology

1975 • 192 citations

The effect of ploidy on chemical mutagenesis in cultured chinese hamster cells

1973 • 139 citations

Unstable amplification of an altered dihydrofolate reductase gene associated with double-minute chromosomes

1981 • 120 citations

Correlation of double-minute chromosomes with unstable multidrug cross-resistance in uptake mutants of neuroblastoma cells.

1981 • 114 citations

Chromosomal and Extrachromosomal Localization of Amplified Dihydrofolate Reductase Genes in Cultured Mammalian Cells

1981 • 112 citations

Antifolate-resistant Chinese hamster cells. Evidence for dihydrofolate reductase gene amplification among independently derived sublines overproducing different dihydrofolate reductases.

1980 • 100 citations

Alterations leading to increased ribonucleotide reductase in cells selected for resistance to deoxynucleosides

1974 • 89 citations

Specifically altered metaphase chromosomes in antifolate-resistant Chinese hamster cells that overproduce dihydrofolate reductase

1980 • 88 citations

Assay of ribonucleotide reduction in nucleotide-permeable hamster cells

1978 • 77 citations

Cytochalasins — biochemical and cell biological aspects

1978 • 56 citations

Isolation and characterization of cells resistant to ML236B (compactin) with increased levels of 3-hydroxy-3-methylglutaryl coenzyme A reductase.

1981 • 53 citations

Alterations in surface proteins during myogenesis of a rat myoblast cell line

1979 • 50 citations

Specific karyotypic alterations in colchicine-resistant cells

1981 • 42 citations

A rapid assay for actin-associated high-affinity cytochalasin binding sites based on isoelectric precipitation of soluble protein

1980 • 18 citations

Variable Content of Double Minute Chromosomes Is Not Correlated with Degree of Phenotype Instability in Methotrexate-Resistant Human Cell Lines

1982 • 16 citations

Genetics of cell fusion: Human chromosome 10 assignment of a gene(FUSE) that promotes polykaryocyte formation

1979 • 4 citations