Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis.

Advanced Organic Chemistry: Reactions, Mechanisms, and Structure

1977 • 4,066 citations

Chemoprevention of Cancer

2008 • 1,269 citations

The Role of Glutathione and Glutathione S-Transferases in the Metabolism of Chemical Carcinogens and Other Electrophilic Agents

1979 • 1,179 citations

The Glutathione S ‐Transferases: A Group of Multifunctional Detoxification Proteins

1978 • 686 citations

Direct measurement of NAD(P)H:quinone reductase from cells cultured in microtiter wells: A screening assay for anticarcinogenic enzyme inducers

1988 • 498 citations

Inhibition of neoplasia by minor dietary constituents.

1983 • 479 citations

Effects of organosulfur compounds from garlic and onions on benzo[a]pyrene-induced neoplasia and glutathione S-transferase activity in the mouse

1988 • 436 citations

Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver.

1988 • 408 citations

Glutathione <italic>S</italic>-Transferase Activity: Enhancement by Compounds Inhibiting Chemical Carcinogenesis and by Dietary Constituents<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref>

1982 • 325 citations

Enzyme-catalysed conjugations of glutathione with unsaturated compounds

1967 • 324 citations

Inhibition of Carcinogenic Effects of Polycyclic Hydrocarbons by Benzyl Isothiocyanate and Related Compounds2

1977 • 309 citations

On the mechanisms of induction of cancer-protective enzymes: a unifying proposal.

1985 • 262 citations

Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) and related 1,2-dithiol-3-thiones and 1,2-dithiol-3-ones.

1987 • 242 citations

Chemoprevention of Cancer

1996 • 180 citations

The metabolism of benzyl isothiocyanate and its cysteine conjugate

1977 • 176 citations

Biochemical effects of dithiolthiones

1986 • 161 citations

Induction of NAD(P)H:quinone reductase in murine hepatoma cells by phenolic antioxidants, azo dyes, and other chemoprotectors: a model system for the study of anticarcinogens.

1986 • 153 citations

Inhibitory effects of 5-(2-pyrazinyl)-4-methyl-1,2-dithioI-3-thione (Oltipraz) on carcinogenesis induced by benzo[a]pyrene, diethylnitrosamine and uracil mustard

1986 • 144 citations

Enzymes catalysing conjugations of glutathione with αβ-unsaturated carbonyl compounds

1968 • 126 citations

Inhibition of chemical carcinogen-induced neoplasia by coumarins and alpha-angelicalactone.

1979 • 107 citations

Enhancement of Glutathione <italic>S</italic>-Transferase Activity of the Mouse Forestomach by Inhibitors of Benzo[<italic>a</italic>]pyrene-Induced Neoplasia of the Forestomach<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref>

1981 • 104 citations

Metabolism of some naturally occurring isothiocyanates in the rat

1983 • 97 citations

Suppression of 7,12-Dimethylbenz(α) Anthracene-Induced Breast Carcinoma by Coumarin in the Rat

1976 • 86 citations

Tissue-specific induction patterns of cancer-protective enzymes in mice by tert-butyl-4-hydroxyanisole and related substituted phenols.

1985 • 70 citations

Enhancement of glutathione S-transferase activity of the esophagus by phenols, lactones, and benzyl isothiocyanate.

1982 • 66 citations

Cancer Biology and Therapeutics

1987 • 66 citations

Effects of disulfiram, diethyldithiocarbamate, bisethylxanthogen, and benzyl isothiocyanate on glutathione transferase activities in mouse organs.

1985 • 55 citations

1, 2-Dithiol-3-thione analogs: effects on NAD(P)H: quinone reductase and glutathione levels in murine hepatoma cells

1986 • 46 citations

Induction of DT-Diaphorase by Anticarcinogenic Sulfur Compounds in Mice<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1986 • 45 citations

Magnetic structure of<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mmultiscripts><mml:mrow><mml:mi mathvariant="normal">O</mml:mi></mml:mrow><mml:mprescripts /><mml:mrow /><mml:mrow><mml:mn>17</mml:mn></mml:mrow><mml:mrow /><mml:mrow /></mml:mmultiscripts></mml:mrow></mml:math>at high momentum

1988 • 37 citations

Specificity of induction of cancer protective enzymes by analogues of tert-butyl-4-hydroxyanisole (BHA)

1985 • 37 citations

Inhibitory Effect of Fumaric Acid on Forestomach and Lung Carcinogenesis by a 5-Nitrofuran Naphthyridine Derivative in Mice

1982 • 16 citations

Inhibitory effect of fumaric acid on 3-methyl-4'-(dimethylamino)-azobenzene-induced hepatocarcinogenesis in rats.

1983 • 12 citations