Crevice‐forming mutants of bovine pancreatic trypsin inhibitor: Stability changes and new hydrophobic surface

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

Solvent-Accessible Surfaces of Proteins and Nucleic Acids

1983 • 2,685 citations

A Method to Identify Protein Sequences That Fold into a Known Three-Dimensional Structure

1991 • 2,629 citations

Stability of Proteins Small Globular Proteins

1979 • 2,139 citations

Solvation energy in protein folding and binding

1986 • 1,853 citations

Solvation thermodynamics of nonionic solutes

1984 • 958 citations

Response of a Protein Structure to Cavity-Creating Mutations and Its Relation to the Hydrophobic Effect

1992 • 933 citations

Hydrophobic bonding and accessible surface area in proteins

1974 • 887 citations

Solubility in Water of Paraffin, Cycloparaffin, Olefin, Acetylene, Cycloolefin, and Aromatic Hydrocarbons¹

1966 • 744 citations

Accessible surface areas as a measure of the thermodynamic parameters of hydration of peptides.

1987 • 737 citations

Theory of hydrophobic bonding. II. Correlation of hydrocarbon solubility in water with solvent cavity surface area

1972 • 694 citations

Use of liquid hydrocarbon and amide transfer data to estimate contributions to thermodynamic functions of protein folding from the removal of nonpolar and polar surface from water

1992 • 542 citations

Reconciling the Magnitude of the Microscopic and Macroscopic Hydrophobic Effects

1991 • 509 citations

Extracting hydrophobic free energies from experimental data: relationship to protein folding and theoretical models

1991 • 431 citations

Cold denaturation of myoglobin

1986 • 408 citations

Hydrogen exchange and the dynamic structure of proteins

1982 • 308 citations

Contribution of hydrogen bonding to the conformational stability of ribonuclease T1

1992 • 273 citations

Characterization of the distribution of internal motions in the basic pancreatic trypsin inhibitor using a large number of internal NMR probes

1983 • 270 citations

A cavity-containing mutant of T4 lysozyme is stabilized by buried benzene

1992 • 265 citations

Contribution of the hydrophobic effect to globular protein stability

1992 • 240 citations

Techniques in Protein Chemistry IV

1993 • 231 citations

Thermodynamics of protein denaturation. Calorimetric study of the reversible denaturation of chymotrypsinogen and conclusions regarding the accuracy of the two-state approximation

1970 • 224 citations

Molecular basis of co-operativity in protein folding

1992 • 166 citations

Partitioning of nonpolar solutes into bilayers and amorphous n-alkanes

1990 • 145 citations

Hydrogen isotope exchange kinetics of single protons in bovine pancreatic trypsin inhibitor

1980 • 126 citations

Kinetics of the exchange of individual amide protons in the basic pancreatic trypsin inhibitor

1979 • 115 citations

Looking at proteins: representations, folding, packing, and design. Biophysical Society National Lecture, 1992.

1992 • 114 citations

X-ray crystal structure of the protease inhibitor domain of Alzheimer's amyloid .beta.-protein precursor

1990 • 110 citations

Structural effects induced by removal of a disulfide-bridge: the X-ray structure of the C30A/C51A mutant of basic pancreatic trypsin inhibitor at 1.6 Å

1990 • 92 citations

Basic pancreatic trypsin inhibitor has unusual thermodynamic stability parameters

1983 • 82 citations

Looking at proteins: representations, folding, packing, and design. Biophysical Society National Lecture, 1992

1992 • 80 citations

A differential scanning calorimetric study of the thermal unfolding of seven mutant forms of phage T4 lysozyme

1991 • 66 citations

Crystal structure of a Y35G mutant of bovine pancreatic trypsin inhibitor

1991 • 61 citations

Effects of Hydrated Water on Protein Unfolding1

1988 • 52 citations

Hydrogen exchange rates in pancreatic trypsin inhibitor are not correlated to thermal stability in urea

1981 • 43 citations

Hydrogen exchange kinetics of surface peptide amides in bovine pancreatic trypsin inhibitor

1987 • 39 citations

Stabilization of the neutral protease of Bacillus stearothermophilus by removal of a buried water molecule

1991 • 27 citations

Crevice‐forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: Crystal structures of F22A, Y23A, N43G, and F45A

1993 • 26 citations

Comparison of solution structures of mutant bovine pancreatic trypsin inhibitor proteins using two‐dimensional nuclear magnetic resonance

1992 • 24 citations