Antiphospholipid antibodies, proteins C and S, and coagulation changes in sickle cell disease

Pain in Sickle Cell Disease

1991 • 1,510 citations

Fundamentals of Biostatistics.

1987 • 1,205 citations

Sickle Cell Disease: Basic Principles and Clinical Practice

1994 • 559 citations

Antiphospholipid antibodies directed against a combination of phospholipids with prothrombin, protein C, or protein S: an explanation for their pathogenic mechanism? [see comments]

1993 • 496 citations

Comparison of the primary and secondary antiphospholipid syndrome: A European multicenter study of 114 patients

1994 • 474 citations

Accelerated autoxidation and heme loss due to instability of sickle hemoglobin.

1988 • 301 citations

Abnormalities in membrane phospholipid organization in sickled erythrocytes.

1981 • 259 citations

Red blood cell changes during the evolution of the sickle cell painful crisis

1992 • 227 citations

Inhibition of activated protein C and its cofactor protein S by antiphospholipid antibodies

1990 • 216 citations

Acquired deficiencies of protein S. Protein S activity during oral anticoagulation, in liver disease, and in disseminated intravascular coagulation.

1988 • 210 citations

Superoxide Dismutase, Glutathione Peroxidase, Catalase and Lipid Peroxidation of Normal and Sickled Erythrocytes

1980 • 193 citations

Uncoupling of the membrane skeleton from the lipid bilayer. The cause of accelerated phospholipid flip-flop leading to an enhanced procoagulant activity of sickled cells.

1985 • 182 citations

Evaluation of Screened Blood Donations for Human Immunodeficiency Virus Type 1 Infection by Culture and DNA Amplification of Pooled Cells

1991 • 174 citations

The Use of a Functional and Immunologic Assay for Plasma Protein C in the Study of the Heterogeneity of Congenital Protein C Deficiency

1984 • 169 citations

Measurement of membrane phospholipid asymmetry in normal and sickle-cell erythrocytes by means of annexin V binding.

1994 • 158 citations

Participation of endothelial cells in the protein C-protein S anticoagulant pathway: the synthesis and release of protein S.

1986 • 157 citations

Protein S deficiency in men with long-term human immunodeficiency virus infection [see comments]

1993 • 154 citations

Phagocytosis of sickle erythrocytes: immunologic and oxidative determinants of hemolytic anemia

1984 • 151 citations

Induction of endothelial cell tissue factor activity by sera from patients with antiphospholipid syndrome: A possible mechanism of thrombosis

1993 • 148 citations

Oral contraceptives and gender affect protein S status

1987 • 147 citations

In vivo externalization of phosphatidylserine and phosphatidylethanolamine in the membrane bilayer and hypercoagulability by the lipid peroxidation of erythrocytes in rats.

1985 • 138 citations

Red cell vesiculation--a common membrane physiologic event.

1986 • 136 citations

Enhanced Lipid Peroxidation in Patients Positive for Antiphospholipid Antibodies

1997 • 113 citations

Coagulation Activation and Fibrinolytic imbalance in Subjects with Idiopathic Antiphospholipid Antibodies -A Crucial Role for Acquired Free Protein S Deficiency

1996 • 109 citations

Subclinical ischaemic episodes during the steady state of sickle cell anaemia.

1992 • 101 citations

Protein S deficiency in men with long-term human immunodeficiency virus infection [see comments]

1993 • 98 citations

Ocular Vaso-occlusive Disease in Primary Antiphospholipid Syndrome

1995 • 96 citations

Phospholipid in the hexagonal II phase is immunogenic: evidence for immunorecognition of nonbilayer lipid phases in vivo.

1990 • 93 citations

Reference Method for the One-Stage Prothrombin Time Test on Human Blood

1976 • 89 citations

A monoclonal IgG anticardiolipin antibody from a patient with the antiphospholipid syndrome is thrombogenic in mice.

1996 • 80 citations

Acquired free protein S deficiency is associated with antiphospholipid antibodies and increased thrombin generation in patients with systemic lupus erythematosus

1995 • 79 citations

Is there an acute-phase response in steady-state sickle cell disease?

1993 • 76 citations

Is sickle cell crisis a thrombotic event?

1986 • 62 citations

Protein C and protein S in homozygous sickle cell disease: does hepatic dysfunction contribute to low levels?

1997 • 62 citations

Alteration of red cell membrane organization in sickle cell anaemia

1986 • 53 citations

Protein S deficiency in sickle cell anemia.

1988 • 53 citations

Antiphospholipid antibodies in sickle cell disease

1993 • 49 citations

Antiphospholipid antibodies (aPL) increase the potential monocyte procoagulant activity in patients with systemic lupus erythematosus

1996 • 48 citations

The effect of spicules obtained from sickle red cells on clotting activity

1984 • 47 citations

Comparison of Functional Assays for Protein S: European Collaborative Study of Patients with Congenital and Acquired Deficiency

1993 • 36 citations

Patterns of anti-phospholipid antibody specificities.

1991 • 36 citations

The distinct pathobiology of sickle cell-hemoglobin C disease. Therapeutic implications.

1991 • 30 citations

Free Protein S Deficiency May Be Found in Patients with Antiphospholipid Antibodies who Do not Have Systemic Lupus Erythematosus

1996 • 29 citations

THE ASSAY AND PROPERTIES OF LABILE FACTOR (FACTOR V)

1960 • 27 citations

Profiles of antibodies to histones, DNA and IgG in patients with systemic rheumatic diseases determined by ELISA.

1985 • 27 citations

Decreased protein S activity in sickle cell disease.

1993 • 22 citations

Antiphospholipid antibodies in homozygous sickle cell disease.

1992 • 21 citations

Physiology of Membrane Lipid Asymmetry

1994 • 19 citations

Antiphospholipid antibodies: lupus anticoagulants, anticardiolipin and antiphospholipid isotypes in patients with sickle cell disease.

1998 • 14 citations

Phase changes in membrane lipids in sickle red cell shed-vesicles and sickle red cells

1998 • 11 citations