Agonist-Induced Expression of Tissue Inhibitor of Metalloproteinases and Metalloproteinases by Human Macrophages Is Regulated by Endogenous Prostaglandin E2 Synthesis

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Polypeptides of the tail fibres of bacteriophage T4

1971 • 956 citations

Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein.

1986 • 645 citations

Human 92- and 72-kilodalton type IV collagenases are elastases.

1991 • 550 citations

Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates.

1985 • 506 citations

Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development.

1990 • 459 citations

Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP)

1991 • 454 citations

The collagen substrate specificity of human skin fibroblast collagenase.

1981 • 371 citations

Cell-matrix interactions modulate interstitial collagenase expression by human keratinocytes actively involved in wound healing.

1993 • 319 citations

MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytes.

1990 • 319 citations

Expression of a metalloproteinase that degrades native type V collagen and denatured collagens by cultured human alveolar macrophages.

1987 • 235 citations

Prostaglandin regulation of macrophage collagenase production.

1977 • 230 citations

Preferential inhibition of 72- and 92-kDa gelatinases by tissue inhibitor of metalloproteinases-2

1991 • 227 citations

Interleukin 4 inhibition of prostaglandin E2 synthesis blocks interstitial collagenase and 92-kDa type IV collagenase/gelatinase production by human monocytes.

1992 • 204 citations

Human alveolar macrophages produce a fibroblast-like collagenase and collagenase inhibitor.

1985 • 199 citations

Suppression of metalloproteinase biosynthesis in human alveolar macrophages by interleukin-4.

1992 • 172 citations

Collagen fractionation: Separation of native types I, II and III by differential prectipitation

1976 • 162 citations

Immune modulation of metalloproteinase production in human macrophages. Selective pretranslational suppression of interstitial collagenase and stromelysin biosynthesis by interferon-gamma.

1990 • 146 citations

Induction of macrophage metalloproteinases by extracellular matrix. Evidence for enzyme- and substrate-specific responses involving prostaglandin-dependent mechanisms.

1993 • 128 citations

Enhanced prostaglandin synthesis after ultraviolet injury is mediated by endogenous histamine stimulation. A mechanism for irradiation erythema.

1990 • 125 citations

Differential susceptibility of type X collagen to cleavage by two mammalian interstitial collagenases and 72-kDa type IV collagenase.

1990 • 121 citations

Calcium ionophore enables soluble agonists to stimulate macrophage 5-lipoxygenase.

1985 • 96 citations

Different patterns of arachidonate metabolism in autologous human blood monocytes and alveolar macrophages.

1989 • 80 citations

Identification of TIMP-2 in human alveolar macrophages. Regulation of biosynthesis is opposite to that of metalloproteinases and TIMP-1.

1992 • 76 citations

Regulation of human peripheral blood monocyte collagenase by prostaglandins and anti-inflammatory drugs

1987 • 64 citations

Expression of Interstitial Collagenase, 92-kDa Gelatinase, and Tissue Inhibitor of Metalloproteinases-1 in Granuloma Annulare and Necrobiosis Lipoidica Diabeticorum

1993 • 62 citations

Arachidonic Acid Metabolism in Normal Human Alveolar Macrophages: Stimulus Specificity for Mediator Release and Phospholipid Metabolism, and Pharmacologic Modulation In Vitro and In Vivo

1990 • 43 citations

Inhibition of phospholipase activity in human monocytes by IFN-gamma blocks endogenous prostaglandin E2-dependent collagenase production.

1990 • 41 citations