Apoptosis mediators FasL and TRAIL are upregulated in peripheral blood mononuclear cells in MS

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

New diagnostic criteria for multiple sclerosis: Guidelines for research protocols

1983 • 7,404 citations

The Receptor for the Cytotoxic Ligand TRAIL

1997 • 1,755 citations

An Antagonist Decoy Receptor and a Death Domain-Containing Receptor for TRAIL

1997 • 1,506 citations

TNF neutralization in MS

1999 • 968 citations

Fas ligand mediates activation-induced cell death in human T lymphocytes.

1995 • 949 citations

The Novel Receptor TRAIL-R4 Induces NF-κB and Protects against TRAIL-Mediated Apoptosis, yet Retains an Incomplete Death Domain

1997 • 829 citations

Cloning and Characterization of TRAIL-R3, a Novel Member of the Emerging TRAIL Receptor Family

1997 • 634 citations

Kinetics of Response in Lymphoid Tissues to Antiretroviral Therapy of HIV-1 Infection

1997 • 631 citations

Potential Involvement of Fas and Its Ligand in the Pathogenesis of Hashimoto's Thyroiditis

1997 • 584 citations

The Role of Fas in Autoimmune Diabetes

1997 • 503 citations

Clinical, Immunologic, and Genetic Features of an Autoimmune Lymphoproliferative Syndrome Associated With Abnormal Lymphocyte Apoptosis

1997 • 374 citations

Multiple Sclerosis: Fas Signaling in Oligodendrocyte Cell Death

1996 • 362 citations

Tumor necrosis factor‐α messenger RNA expression in patients with relapsing‐remitting multiple sclerosis is associated with disease activity

1995 • 336 citations

TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL

1997 • 331 citations

A rapid and versatile method to synthesize internal standards for competitive PCR

1993 • 318 citations

Oligodendrocyte Apoptosis and Primary Demyelination Induced by Local TNF/p55TNF Receptor Signaling in the Central Nervous System of Transgenic Mice

1998 • 317 citations

TRAIL/Apo-2-ligand-induced apoptosis in human T cells

1998 • 273 citations

Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis.

1997 • 204 citations

Multiple sclerosis: Oligodendrocytes display cell death–related molecules in situ but do not undergo apoptosis

1997 • 204 citations

Activation of apoptosis by Apo-2 ligand is independent of FADD but blocked by CrmA

1996 • 198 citations

Involvement of APO2 ligand/TRAIL in activation-induced death of Jurkat and human peripheral blood T cells

1998 • 188 citations

Cell death and birth in multiple sclerosis brain

1997 • 127 citations

Genetically determined failure of activation-induced apoptosis of autoreactive T cells as a cause of multiple sclerosis

1998 • 108 citations

Multiple sclerosis: expression of molecules of the tumor necrosis factor ligand and receptor families in relationship to the demyelinated plaque.

1998 • 80 citations

Apoptosis and autoimmune disease

1999 • 75 citations

The Biology of the Immune System

1997 • 75 citations

Increased serum levels of soluble CD95 (APO‐1/Fas) in relapsing‐remitting multiple sclerosis

1998 • 72 citations

Tumour necrosis factor and lymphotoxin: Molecular aspects and role in tissue‐specific autoimmunity

1996 • 68 citations

The roles of Fas, Fas ligand and Bcl-2 in T cell apoptosis in the central nervous system in experimental autoimmune encephalomyelitis

1998 • 65 citations

Increased Fas antigen on T cells in multiple sclerosis

1996 • 62 citations

Soluble Fas (Apo-1) levels in cerebrospinal fluid of multiple sclerosis patients

1998 • 60 citations

Deficient Fas ligand expression by synovial lymphocytes from patients with rheumatoid arthritis

1997 • 56 citations

The bc1-2 Proto-Oncogene is Overexpressed in Systemic Lupus Erythematosus

1994 • 45 citations

The pattern of production of cytokine mRNAs is markedly altered at the onset of multiple sclerosis

1996 • 30 citations

CD95 expression and CD95-mediated apoptosis of T cells in multiple sclerosis

1998 • 22 citations

Serum sAPO-1/Fas levels in multiple sclerosis

1997 • 20 citations

Expression of costimulatory molecules and cytokines in CSF and peripheral blood mononuclear cells from multiple sclerosis patients.

1999 • 9 citations