Nuclear localization of human AP endonuclease 1 (HAP1/Ref-1) associates with prognosis in early operable non-small cell lung cancer (NSCLC)

Cancer: Principles and Practice of Oncology.

1991 • 8,402 citations

Molecular biology of the cell

1993 • 2,383 citations

Fos and jun: The AP-1 connection

1988 • 1,597 citations

REPAIR OF OXIDATIVE DAMAGE TO DNA: Enzymology and Biology

1994 • 1,435 citations

Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme.

1992 • 920 citations

MUTAGENESIS BY APURINIC/APYRIMIDINIC SITES

1986 • 884 citations

Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity.

1992 • 702 citations

Hypoxic fractions of solid tumors: Experimental techniques, methods of analysis, and a survey of existing data

1984 • 610 citations

Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes.

1991 • 526 citations

Identification of redox/repair protein Ref-1 as a potent activator of p53.

1997 • 479 citations

The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains.

1994 • 351 citations

Isolation of cDNA clones encoding a human apurini/apyrimidinic endonuclease that corects DNA repair and mutagenisis defects inE.coli xth(exonuclease III) mutants

1991 • 294 citations

Activation of p53 gene expression in premalignant lesions during head and neck tumorigenesis.

1994 • 272 citations

Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding.

1993 • 270 citations

Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia.

1994 • 241 citations

A role for the human DNA repair enzyme HAP1 in cellular protection against DNA damaging agents and hypoxic stress

1994 • 221 citations

Methylation-induced blocks to in vitro DNA replication

1985 • 220 citations

Bcl-2 protein: a prognostic factor inversely correlated to p53 in non-small-cell lung cancer

1995 • 201 citations

PROGNOSTIC VALUE OF ANGIOGENESIS IN OPERABLE NON-SMALL CELL LUNG CANCER

1996 • 176 citations

Mitochondrial endonuclease activities specific for apurinic/apyrimidinic sites in DNA from mouse cells.

1988 • 152 citations

The relationship of p53 immunostaining to survival in carcinoma of the lung

1992 • 147 citations

Altered cJun expression: An early event in human lung carcinogenesis

1996 • 116 citations

cDNA and deduced amino acid sequence of a mouse DNA repair enzyme (APEX nuclease) with significant homology to Escherichia coli exonuclease III.

1991 • 109 citations

Ki‐67 immunostaining and survival in operable lung cancer

1991 • 88 citations

Differential cellular and subcellular expression of the human multifunctional apurinic/apyrimidinic endonuclease (APE/ref-1) DNA repair enzyme.

1995 • 87 citations

Expression and subcellular localization of human AP endonuclease 1 (HAP1/Ref‐1) protein: a basis for its role in human disease

1998 • 83 citations

A ubiquitous nuclear protein stimulates the DNA-binding activity of fos and jun indirectly.

1990 • 76 citations

Human AP endonuclease 1 (HAP1) protein expression in breast cancer correlates with lymph node status and angiogenesis

1998 • 69 citations

Defective repair of oxidative damage in the mitochondrial DNA of a xeroderma pigmentosum group A cell line.

1996 • 60 citations

p53 expression in normal and dysplastic bronchial epithelium and in lung carcinomas

1994 • 58 citations

The prognostic value of quantitative angiogenesis in breast cancer and role of adhesion molecule expression in tumor endothelium

1995 • 58 citations

Human apurinic endonuclease 1 expression in a colorectal adenoma-carcinoma sequence.

1997 • 55 citations

Regulation of AP-1/DNA complex formation in vitro.

1991 • 41 citations

Antibody for detecting p53 protein by immunohistochemistry in normal tissues.

1994 • 36 citations