C-terminal Elements Control Location, Activation Threshold, and p38 Docking of Ribosomal S6 Kinase B (RSKB)

The Protein Data Bank

2000 • 35,287 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

Assessment of protein models with three-dimensional profiles

1992 • 3,317 citations

CLUSTAL V: improved software for multiple sequence alignment

1992 • 2,421 citations

Tertiary templates for proteins

1987 • 1,485 citations

Signal transduction via the MAP kinases: proceed at your own RSK.

1993 • 1,262 citations

Coupling of the RAS-MAPK Pathway to Gene Activation by RSK2, a Growth Factor-Regulated CREB Kinase

1996 • 1,253 citations

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activationofCREB

1998 • 975 citations

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

1997 • 927 citations

MAP kinase pathways

1999 • 875 citations

Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction

1999 • 722 citations

MAB, a generally applicable molecular force field for structure modelling in medicinal chemistry

1995 • 573 citations

Nerve Growth Factor Activates Extracellular Signal-Regulated Kinase and p38 Mitogen-Activated Protein Kinase Pathways To Stimulate CREB Serine 133 Phosphorylation

1998 • 495 citations

MAPKAP kinase-2; a novel protein kinase activated by mitogen-activated protein kinase.

1992 • 486 citations

Requirement of Rsk-2 for Epidermal Growth Factor-Activated Phosphorylation of Histone H3

1999 • 478 citations

Identification of Regulatory Phosphorylation Sites in Mitogen-activated Protein Kinase (MAPK)-activated Protein Kinase-1a/p90 That Are Inducible by MAPK

1998 • 359 citations

pp90^rsk1 Regulates Estrogen Receptor-Mediated Transcription through Phosphorylation of Ser-167

1998 • 348 citations

Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2

1998 • 336 citations

Structural Basis for the Autoinhibition of Calcium/Calmodulin-Dependent Protein Kinase I

1996 • 329 citations

A link between MAP kinase and p34cdc2/cyclin B during oocyte maturation: p90rsk phosphorylates and inactivates the p34cdc2 inhibitory kinase Myt1

1998 • 319 citations

Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution

1998 • 309 citations

Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c- fos gene

1998 • 302 citations

Blockade of p38 Mitogen-activated Protein Kinase Pathway Inhibits Inducible Nitric-oxide Synthase Expression in Mouse Astrocytes

1997 • 300 citations

Sequences of autophosphorylation sites in neuronal type II CaM kinase that control Ca2+-independent activity

1988 • 283 citations

Identification of an Extracellular Signal-regulated Kinase (ERK) Docking Site in Ribosomal S6 Kinase, a Sequence Critical for Activation by ERK in Vivo

1999 • 281 citations

Leptomycin B-sensitive nuclear export of MAPKAP kinase 2is regulated by phosphorylation

1998 • 270 citations

The Signal-Dependent Coactivator CBP Is a Nuclear Target for pp90RSK

1996 • 254 citations

90-kDa Ribosomal S6 Kinase Is Phosphorylated and Activated by 3-Phosphoinositide-dependent Protein Kinase-1

1999 • 254 citations

Neurotransmitter- and Growth Factor-Induced cAMP Response Element Binding Protein Phosphorylation in Glial Cell Progenitors: Role of Calcium Ions, Protein Kinase C, and Mitogen-Activated Protein Kinase/Ribosomal S6 Kinase Pathway

1997 • 189 citations

Evidence for Two Catalytically Active Kinase Domains in pp90^rsk

1996 • 188 citations

Identification of p90RSK as the probable CREB-Ser133 kinase in human melanocytes.

1995 • 174 citations

RSK-B, a Novel Ribosomal S6 Kinase Family Member, Is a CREB Kinase under Dominant Control of p38α Mitogen-activated Protein Kinase (p38αMAPK)

1998 • 164 citations

Substrate-directed Function of Calmodulin in Autophosphorylation of Ca2+/Calmodulin-dependent Protein Kinase II

1998 • 163 citations

Regulation and Interaction of pp90 Isoforms with Mitogen-activated Protein Kinases

1996 • 162 citations

A MAP kinase docking site is required for phosphorylation and activation of p90rsk/MAPKAP kinase-1

1999 • 157 citations

Structural Examination of Autoregulation of Multifunctional Calcium/Calmodulin-dependent Protein Kinase II

1999 • 152 citations

Linkage Mapping in 29 Bardet–Biedl Syndrome Families Confirms Loci in Chromosomal Regions 11q13, 15q22.3–q23, and 16q21

1997 • 124 citations

A Novel Ribosomal S6-Kinase (RSK4; RPS6KA6) Is Commonly Deleted in Patients with Complex X-Linked Mental Retardation

1999 • 117 citations

Constitutive Activation of Mitogen-activated Protein Kinase-activated Protein Kinase 2 by Mutation of Phosphorylation Sites and an A-helix Motif

1995 • 115 citations

Charge distribution from a simple molecular orbital type calculation and non-bonding interaction terms in the force field MAB.

1998 • 108 citations

Different ARF Domains Are Required for the Activation of Cholera Toxin and Phospholipase D

1995 • 93 citations

A conserved helix motif complements the protein kinase core.

1993 • 71 citations

Generation of Constitutively Active p90 Ribosomal S6 Kinasein Vivo

1999 • 67 citations

Cloning and Characterization of RLPK, a Novel RSK-related Protein Kinase

1999 • 52 citations

A p90^rskMutant Constitutively Interacting with MAP Kinase Uncouples MAP Kinase from p34^cdc2/Cyclin B Activation inXenopusOocytes

1999 • 43 citations

Control Sites of Ribosomal S6 Kinase B and Persistent Activation through Tumor Necrosis Factor

2000 • 33 citations

A transcript map of an 800-kb region on human chromosome 11q13, part of the candidate region for SCA5 and BBS1

1998 • 13 citations