Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues

Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor

1999 • 6,443 citations

A C. elegans mutant that lives twice as long as wild type

1993 • 3,250 citations

daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans

1997 • 2,174 citations

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

1997 • 1,905 citations

daf-16 : An HNF-3/forkhead Family Member That Can Function to Double the Life-Span of Caenorhabditis elegans

1997 • 1,468 citations

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

1999 • 1,102 citations

Direct control of the Forkhead transcription factor AFX by protein kinase B

1999 • 1,080 citations

A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility.

1988 • 958 citations

Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma

1993 • 884 citations

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

1996 • 870 citations

Negative Regulation of the Forkhead Transcription Factor FKHR by Akt

1999 • 763 citations

Thedaf‐2gene network for longevity regulates oxidative stress resistance and Mn‐superoxide dismutase gene expression inCaenorhabditis elegans

1999 • 721 citations

Phosphorylation of the Transcription Factor Forkhead Family Member FKHR by Protein Kinase B

1999 • 719 citations

Regulation of gene expression by insulin

1996 • 543 citations

Phosphorylation of Serine 256 by Protein Kinase B Disrupts Transactivation by FKHR and Mediates Effects of Insulin on Insulin-like Growth Factor-binding Protein-1 Promoter Activity through a Conserved Insulin Response Sequence

1999 • 542 citations

Insulin Stimulates Phosphorylation of the Forkhead Transcription Factor FKHR on Serine 253 through a Wortmannin-sensitive Pathway

1999 • 470 citations

Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.

1994 • 430 citations

Cell Nonautonomy of C. elegans daf-2 Function in the Regulation of Diapause and Life Span

1998 • 362 citations

Longevity, Genes, and Aging

1996 • 352 citations

Cloning and Characterization of Three Human Forkhead Genes That Comprise an FKHR-like Gene Subfamily

1998 • 350 citations

Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)

1997 • 247 citations

Akt2 mRNA is highly expressed in embryonic brown fat and the AKT2 kinase is activated by insulin

1998 • 129 citations

Expression of copper trafficking genes in the mouse brain

1998 • 58 citations