MEKK3 Directly Regulates MEK5 Activity as Part of the Big Mitogen-activated Protein Kinase 1 (BMK1) Signaling Pathway

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1994 • 3,219 citations

Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human

1999 • 2,692 citations

A MAP Kinase Targeted by Endotoxin and Hyperosmolarity in Mammalian Cells

1994 • 2,659 citations

Differential Activation of ERK and JNK Mitogen-Activated Protein Kinases by Raf-1 and MEKK

1994 • 1,092 citations

MAP kinase pathways

1999 • 875 citations

Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation

1997 • 770 citations

An Insulin-Stimulated Protein Kinase Similar to Yeast Kinases Involved in Cell Cycle Control

1990 • 701 citations

Components of a New Human Protein Kinase Signal Transduction Pathway

1995 • 644 citations

BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C

1997 • 580 citations

Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor

1998 • 446 citations

Big Mitogen-activated Protein Kinase 1 (BMK1) Is a Redox-sensitive Kinase

1996 • 445 citations

Transcriptional regulation by MAP kinases

1995 • 431 citations

Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals

1998 • 395 citations

Primary Structure of BMK1: A New Mammalian MAP Kinase

1995 • 345 citations

Regulation of the ERK Subgroup of MAP Kinase Cascades Through G Protein-Coupled Receptors

1997 • 323 citations

Definition of the human raf amino-terminal regulatory region by deletion mutagenesis.

1989 • 240 citations

Molecular Cloning of Mitogen-activated Protein/ERK Kinase Kinases (MEKK) 2 and 3

1996 • 227 citations

Isolation of MEK5 and Differential Expression of Alternatively Spliced Forms

1995 • 221 citations

14-3-3 Proteins Interact with Specific MEK Kinases

1998 • 146 citations

Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain.

1996 • 134 citations

The TAO of MEKK

1998 • 132 citations

Activation of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase by G protein and tyrosine kinase oncoproteins.

1993 • 130 citations

Direct Activation of the Stress-activated Protein Kinase (SAPK) and Extracellular Signal-regulated Protein Kinase (ERK) Pathways by an Inducible Mitogen-activated Protein Kinase/ERK Kinase Kinase 3 (MEKK) Derivative

1997 • 101 citations

Functional Mapping of the N-terminal Regulatory Domain in the Human Raf-1 Protein Kinase

1995 • 68 citations

The Raf-1 serine/threonine protein kinase.

1994 • 67 citations