Cell type dependent transcription regulation by chick homeodomain proteins

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Assay of proteins in the presence of interfering materials

1976 • 3,217 citations

DNA cloning : a practical approach

1985 • 2,302 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Mechanism of transcriptional activation by Sp1: Evidence for coactivators

1990 • 1,029 citations

The molecular basis for metameric pattern in the Drosophila embryo

1987 • 1,028 citations

The murine and Drosophila homeobox gene complexes have common features of organization and expression

1989 • 1,021 citations

Crystal structure of an engrailed homeodomain-DNA complex at 2.8 Å resolution: A framework for understanding homeodomain-DNA interactions

1990 • 996 citations

The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes.

1989 • 912 citations

Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5

1991 • 856 citations

The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain

1989 • 781 citations

New type of POU domain in germ line-specific protein Oct-4

1990 • 753 citations

A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells

1990 • 745 citations

The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo

1989 • 672 citations

Molecular interactions of steroid hormone receptor with its enhancer element: Evidence for receptor dimer formation

1988 • 600 citations

Murine Developmental Control Genes

1990 • 594 citations

A single amino acid can determine the DNA binding specificity of homeodomain proteins

1989 • 531 citations

The sequence specificity of homeodomain-DNA interaction

1988 • 501 citations

Divergent homeo box proteins recognize similar DNA sequences in Drosophila

1988 • 491 citations

DNA specificity of the bicoid activator protein is determined by homeodomain recognition helix residue 9

1989 • 487 citations

The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: Comparison with prokaryotic repressors

1989 • 468 citations

POU-domain transcription factors: pou-er-ful developmental regulators.

1991 • 461 citations

Protein-DNA contacts in the structure of a homeodomain-DNA complex determined by nuclear magnetic resonance spectroscopy in solution.

1990 • 460 citations

A novel mediator between activator proteins and the RNA polymerase II transcription apparatus

1990 • 450 citations

HOMEOTIC GENES AND THE HOMEOBOX

1986 • 442 citations

Expression of the homeobox Hox-4 genes and the specification of position in chick wing development

1991 • 394 citations

The Drosophila developmental gene, engrailed, encodes a sequence-specific DNA binding activity

1985 • 387 citations

Absence of the type I IFN system in EC cells: Transcriptional activator (IRF-1) and repressor (IRF-2) genes are developmentally regulated

1990 • 377 citations

Variations of cervical vertebrate after expression of a Hox-1.1 transgene in mice

1990 • 371 citations

Synergistic activation and repression of transcription by Drosophila homeobox proteins

1989 • 353 citations

Establishment and characterization of a chicken hepatocellular carcinoma cell line, LMH.

1987 • 322 citations

The human HOX gene family

1989 • 317 citations

Homeobox gene expression correlated with the bifurcation process of limb cartilage development

1991 • 317 citations

Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: Evidence for transcriptional adaptors

1990 • 312 citations

Transcriptional activation and repression by Ultrabithorax proteins in cultured Drosophila cells

1989 • 291 citations

Functional dissection of ultrabithorax proteins in D. melanogaster

1990 • 255 citations

Oct-6: a POU transcription factor expressed in embryonal stem cells and in the developing brain.

1990 • 238 citations

Human Hox-4.2 and Drosophila Deformed encode similar regulatory specificities in Drosophila embryos and larvae

1990 • 225 citations

Involvement of the Chox-4 chicken homeobox genes in determination of anteroposterior axial polarity during limb development

1991 • 223 citations

Isolation and sequence-specific DNA binding of the Antennapedia homeodomain.

1988 • 221 citations

Activation and repression of transcription by homoeodomain-containing proteins that bind a common site

1988 • 217 citations

Mouse homeo-genes within a subfamily, Hox-1.4, -2.6 and -5.1, display similar anteroposterior domains of expression in the embryo, but show stage- and tissue-dependent differences in their regulation

1989 • 192 citations

Mouse Hox-2.2 specifies thoracic segmental identity in Drosophila embryos and larvae

1990 • 182 citations

A mouse embryonic stem cell line showing pluripotency of differentiation in early embryos and ubiquitous β-galactosidase expression

1990 • 177 citations

An Ultrabithorax protein binds sequences near its own and the Antennapedia P1 promoters

1988 • 166 citations

A homeodomain substitution changes the regulatory specificity of the Deformed protein in drosophila embryos

1989 • 142 citations

3. Teratocarcinomas and Embryonic Stem Cells

2016 • 141 citations

The Hox-1.3 homeo box protein is a sequence-specific DNA-binding phosphoprotein.

1989 • 139 citations

Transcriptional activation by the Antennapedia and fushi tarazu proteins in cultured Drosophila cells

1989 • 129 citations

Differential utilization of the same reading frame in a Xenopus homeobox gene encodes two related proteins sharing the same DNA-binding specificity.

1988 • 129 citations

Structure and expression of the rat c-jun messenger RNA: tissue distribution and increase during chemical hepatocarcinogenesis.

1989 • 121 citations

Retinoic acid-binding protein, rhombomeres and the neural crest

1991 • 114 citations

Expression of a homeobox gene in the chick wing bud following application of retinoic acid and grafts of polarizing region tissue.

1990 • 106 citations

Rescue of bicoid mutant Drosophila embryos by Bicoid fusion proteins containing heterologous activating sequences

1989 • 100 citations

Overexpression of a homeodomain protein confers axis-forming activity to uncommitted xenopus embryonic cells

1991 • 88 citations

Binding site-dependent direct activation and repression of in vitro transcription by Drosophila homeodomain proteins

1990 • 78 citations

Gene activation and DNA binding by Drosophila Ubx and abd-A proteins

1989 • 77 citations

A negative regulatory sequence near the mouse beta-maj globin gene associated with a region of potential Z-DNA.

1984 • 52 citations

Specific DNA binding of the two chickenDeformedfamily homeodomain proteins,Chox-1.4 andChox-a

1990 • 32 citations

Direct evidence that the kinase activity of protein kinase C is involved in transcriptional activation through a TPA‐responsive element

1989 • 30 citations

The nucleotide sequence of the cDNA encoding a chickenDeformedfamily homeobox gene,Chox-Z

1990 • 20 citations