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The Role of Adenosine in the Regulation of Cerebral Blood Flow

Data up to Jan 2025

Published1981
Citations236
References42

Total Citations Per Year

Abstract

References (42)

Cardiac nucleotides in hypoxia: possible role in regulation of coronary blood flow

1963 • 1,015 citations

The effect of adenosine and adenine nucleotides on the cyclic adenosine 3', 5'-phosphate content of guinea pig cerebral cortex slices.

1970 • 860 citations

Release of Adenosine from Ischemic Brain

1974 • 514 citations

CEREBRAL BLOOD FLOW AND METABOLIC RATE EARLY AND LATE IN PROLONGED EPILEPTIC SEIZURES INDUCED IN RATS BY BICUCULLINE

1976 • 296 citations

Perivascular Potassium and pH as Determinants of Local Pial Arterial Diameter in Cats

1972 • 286 citations

Activities and some properties of 5′-nucleotidase, adenosine kinase and adenosine deaminase in tissues from vertebrates and invertebrates in relation to the control of the concentration and the physiological role of adenosine

1978 • 270 citations

EFFECTS OF CAFFEINE ON MAMMALIAN ATRIAL MUSCLE, AND ITS INTERACTION WITH ADENOSINE AND CALCIUM.

1965 • 242 citations

Independent blood-brain barrier transport systems for nucleic acid precursors

1975 • 238 citations

Glial cell function: Active control of extracellular K+ concentration

1972 • 233 citations

Cerebral microcirculation and metabolism

1982 • 227 citations

Physiological and Regulatory Functions of Adenosine and Adenine Nucleotides

1979 • 222 citations

Brain adenosine production in the rat during 60 seconds of ischemia.

1979 • 213 citations

CYCLIC AMP AND SMOOTH MUSCLE FUNCTION*

1971 • 203 citations

Relationship between adenosine concentration and oxygen supply in rat brain

1975 • 202 citations

Changes in brain adenosine during bicuculline-induced seizures in rats. Effects of hypoxia and altered systemic blood pressure.

1980 • 196 citations

Metabolism of [14C]adenine and derivatives by cerebral tissues, superfused and electrically stimulated

1972 • 193 citations

Cytochemical localization of 5′-nucleotidase in glial plasma membranes

1978 • 179 citations

The dilatatory action of adenosine on pial arteries of cats and its inhibition by theophylline

1976 • 175 citations

Uptake and metabolism of adenosine by human erythrocyte ghosts

1972 • 173 citations

Inhibition of slow action potentials of guinea pig atrial muscle by adenosine: A possible effect on Ca2+ influx

1975 • 157 citations

A potent depressant action of adenine derivatives on cerebral cortical neurones

1975 • 152 citations

5'-Nucleotidase from smooth muscle of small intestine and from brain. Inhibition by nucleotides

1975 • 134 citations

Adenosine relaxation of isolated vascular smooth muscle

1976 • 131 citations

The purine nucleotide cycle. Studies of ammonia production and interconversions of adenine and hypoxanthine nucleotides and nucleosides by rat brain in situ.

1978 • 127 citations

Increase of adenosine content in cerebral cortex of the cat during bicuculline-induced seizure

1980 • 122 citations

Sheep brain 5'-nucleotidase. Enzymic properties and allosteric inhibition by nucleoside triphosphates

1968 • 107 citations

Coronary Vasodilator Properties of Purine and Pyrimidine Derivatives

1956 • 104 citations

CENTRAL NERVOUS SYSTEM. STUDIES ON METABOLIC REGULATION AND FUNCTION

1974 • 102 citations

In Vitro Regulation of Rat Heart 5'-Nucleotidase by Adenine Nucleotides and Magnesium

1971 • 93 citations

Canine myocardial adenosine and lactate production, oxygen consumption, and coronary blood flow during stellate ganglia stimulation.

1979 • 83 citations

Adenosine and cyclic AMP in cerebral cortex of rats in hypoxia, status epilepticus and hypercapnia

1978 • 63 citations

Evidence Against H + and K + as main Factors for the Control of Cerebral Blood Flow: A Microelectrode Study

1978 • 62 citations

Increased adenosine formation by rat myocardium with acute aortic constriction

1978 • 61 citations

Blockade of Ca2+ dependent rat atrial slow action potentials by adenosine and lanthanum

1979 • 52 citations

Adenine compounds: cerebrovascular effects in vitro with reference to their possible involvement in migraine.

1979 • 47 citations

Perivascular pH and pial arterial diameter during bicuculline induced seizures in cats

1979 • 43 citations

Unimportance of perivascular H+ and K+ activities for the adjustment of pial arterial diameter during changes of arterial blood pressure in cats

1979 • 40 citations

Uptake of adenosine by dispersed chich embryonic cardiac cells

1975 • 28 citations

Adenosine response on pial arteries, influence of CO2 and blood pressure

1980 • 26 citations

Production, Metabolism and Possible Functions of Adenosine in Brain Tissue in situ

1978 • 26 citations

Kinetic properties of cerebral 5′‐nucleotidase

1972 • 23 citations

Methyltransferase Enzymes in the Metabolism of Physiologically Active Compounds and Drugs

1971 • 13 citations

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The Role of Adenosine in the Regulation of Cerebral Blood Flow (1981) – Journal of Cerebral Blood Flow & Metabolism | Metascience Observatory Explorer