The potential role of interleukin‐13 in eosinophilic inflammation in nasal mucosa

Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.

1993 • 1,084 citations

lnterleukin-13 is a new human lymphokine regulating inflammatory and immune responses

1993 • 877 citations

IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium. Association with expression of VCAM-1.

1992 • 838 citations

Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFN-gamma or IL-10.

1993 • 657 citations

An improved immunomagnetic procedure for the isolation of highly purified human blood eosinophils

1991 • 628 citations

Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function.

1993 • 565 citations

IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells.

1995 • 424 citations

Nasal mast cells in perennial allergic rhinitics exhibit increased expression of the Fc epsilonRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells.

1997 • 347 citations

Interleukin 13 is a B cell stimulating factor.

1994 • 298 citations

Mechanisms of eosinophil adherence to cultured vascular endothelial cells. Eosinophils bind to the cytokine-induced ligand vascular cell adhesion molecule-1 via the very late activation antigen-4 integrin receptor.

1991 • 268 citations

Multiple activation states of VLA-4. Mechanistic differences between adhesion to CS1/fibronectin and to vascular cell adhesion molecule-1.

1993 • 266 citations

IL-13 induces proliferation and differentiation of human B cells activated by the CD40 ligand

1993 • 260 citations

Eosinophil transendothelial migration induced by cytokines. III. Effect of the chemokine RANTES.

1994 • 175 citations

Identification, Purification, and Characterization of a Soluble Interleukin (IL)-13-binding Protein

1997 • 154 citations

Endobronchial secretion of interleukin-13 following local allergen challenge in atopic asthma: relationship to interleukin-4 and eosinophil counts

1996 • 144 citations

Activation of human eosinophils by IL-13. Induction of CD69 surface antigen, its relationship to messenger RNA expression, and promotion of cellular viability.

1996 • 134 citations

Interleukin-13 expression in the nasal mucosa of perennial allergic rhinitis.

1995 • 124 citations

Regulation of endothelial and mesothelial cell function by interleukin- 13: selective induction of vascular cell adhesion molecule-1 and amplification of interleukin-6 production

1994 • 116 citations

The effect of recombinant human interleukin-5 on eosinophil accumulation and degranulation in human nasal mucosa

1992 • 59 citations

Biochemical properties of eosinophils and their preferential accumulation mechanism in nasal allergy

1994 • 59 citations

Granulocyte-macrophage colony-stimulating factor regulates the functional adhesive state of very late antigen-4 expressed by eosinophils.

1997 • 43 citations

Establishment of human mucosal microvascular endothelial cells from inferior turbinate in culture

1989 • 25 citations

Eosinophil adhesion regulates RANTES production in nasal epithelial cells.

1997 • 24 citations