Role of proteolytic enzymes in biological regulation (a review).

Atlas of Protein Sequence and Structure, 1972.

1973 • 2,408 citations

Proteases and biological control

1976 • 1,380 citations

Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components.

1975 • 1,175 citations

An Enzyme Cascade in the Blood Clotting Mechanism, and its Function as a Biochemical Amplifier

1964 • 1,099 citations

Waterfall Sequence for Intrinsic Blood Clotting

1964 • 1,088 citations

Control of Enzyme Levels in Animal Tissues

1970 • 680 citations

The Preparation of Subtilisin-modified Ribonuclease and the Separation of the Peptide and Protein Components

1959 • 632 citations

Complement

1975 • 594 citations

Crystal structure of the complex of porcine trypsin with soybean trypsin inhibitor (Kunitz) at 2.6 Å resolution

1974 • 431 citations

Subtilisin. Stereochemical mechanism involving transition-state stabilization

1972 • 376 citations

Basic Mechanisms in Blood Coagulation

1975 • 366 citations

Chymotrypsinogen: 2,5-Å crystal structure, comparison with α-chymotrypsin, and implications for zymogen activation

1970 • 345 citations

THE PREPARATION, PURIFICATION, AND AMINO ACID SEQUENCE OF A POLYPEPTIDE RENIN SUBSTRATE

1957 • 320 citations

Primary structure of the vitamin K-dependent part of prothrombin

1974 • 289 citations

Homology in amino-terminal sequence of precursors to pancreatic secretory proteins.

1975 • 272 citations

Determination of the amino acid sequence of porcine trypsin by sequenator analysis

1973 • 259 citations

Mechanism of Activation of Human Plasminogen by Streptokinase

1972 • 248 citations

Purification and Specificity of Porcine Enterokinase

1971 • 224 citations

Evolution of Structure and Function of Proteases

1967 • 197 citations

Zymogen of tadpole collagenase

1971 • 194 citations

The Control of Morphogenesis: An Enzymatic Mechanism for the Initiation of Septum Formation in Yeast

1971 • 182 citations

Zymogens of Proteolytic Enzymes

1973 • 168 citations

Isolation of a Glucagon-containing Peptide: Primary Structure of a Possible Fragment of Proglucagon

1973 • 165 citations

The phylogeny of trypsin-related serine proteases and their zymogens. New methods for the investigation of distant evolutionary relationships

1975 • 152 citations

Pre-proparathyroid hormone: Analysis of radioactive tryptic peptides and amino acid sequence

1976 • 120 citations

Studies on phospholipase A and its zymogen from porcine pancreas

1970 • 113 citations

Bovine factor X1 (Stuart factor): amino-acid sequence of heavey chain.

1975 • 113 citations

Proacrosin from Rabbit Epididymal Spermatozoa: Partial Purification and Initial Biochemical Characterization1

1975 • 99 citations

Vitamin K and the Biosynthesis of Prothrombin

1974 • 89 citations

Catalysis by chymotrypsinogen. Demonstration of an acyl-zymogen intermediate

1974 • 85 citations

The preparation of activated Factor X and its action on prothrombin

1973 • 81 citations

Bovine factor X1 (Stuart factor). Primary structure of the light chain.

1975 • 78 citations

The Interaction of Streptokinase with Human, Cat, Dog, and Rabbit Plasminogens

1974 • 78 citations

Amino acid sequence of dogfish trypsin

1975 • 77 citations

Inactivation of Bovine Trypsinogen and Chymotrypsinogen by Diisopropylphosphorofluoridate

1972 • 73 citations

Partial purification of bovine plasma kallikreinogen, its activation by the Hageman factor

1968 • 72 citations

Studies on prephenoloxidase-activating enzyme from cuticle of the silkworm Bombyx mori,

1973 • 70 citations

The Activation of a Possible Zymogen of Renin in Rabbit Kidney

1973 • 66 citations

Relation of the α-amino group of trypsin to enzyme function and zymogen activation

1973 • 64 citations

-Chymotrypsin: What Can We Learn about Catalysis from X-Ray Diffraction?

1972 • 61 citations

Bovine factor X₁a (activated Stuart factor). Evidence of homology with mammalian serine proteases

1972 • 56 citations

Cocoonase

1973 • 55 citations

Biosynthesis of Melittin, a Toxic Peptide from Bee Venom

1973 • 50 citations

The Primary Structure of Human Plasminogen

1972 • 44 citations

The Primary Structure of Human Plasminogen

1973 • 44 citations

Carboxypeptidase inhibitor from potatoes. The effects of chemical modifications on inhibitory activity

1976 • 40 citations

Catalysis by serine proteases and their zymogens. Study of acyl intermediates by circular dichroism

1975 • 40 citations

Cocoonase

1973 • 39 citations

Bovine factor IX (christmas factor). Further evidence of homology with factor X (Stuart factor) and prothrombin

1974 • 38 citations

Peroxidase, "protyrosinase," and the multiple forms of tyrosinase in mice.

1973 • 31 citations

Partial sequence of the precursors of immunoglobulin light-chains of different subgroups: Evidence that the immunoglobulin variable-region gene is larger than hitherto known

1976 • 29 citations

Metabolic interconversion of enzymes 1975

1977 • 20 citations

Inactivation of trypsinogen by methane sulfonyl fluoride

1974 • 14 citations

The structure and assembly of procollagen – a review

1974 • 12 citations

The tyrosinase-protyrosinase system in frog epidermis.

1973 • 8 citations