Inhibition of Bladder Tumor Growth by 1,1-Bis(3′-Indolyl)-1-(p-Substitutedphenyl)Methanes: A New Class of Peroxisome Proliferator-Activated Receptor γ Agonists

Gemcitabine and Cisplatin Versus Methotrexate, Vinblastine, Doxorubicin, and Cisplatin in Advanced or Metastatic Bladder Cancer: Results of a Large, Randomized, Multinational, Multicenter, Phase III Study

2000 • 2,162 citations

Minireview: Lipid Metabolism, Metabolic Diseases, and Peroxisome Proliferator-Activated Receptors

2003 • 864 citations

Ligands for peroxisome proliferator-activated receptorγ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice

1998 • 807 citations

Methotrexate, vinblastine, doxorubicin, and cisplatin for advanced transitional cell carcinoma of the urothelium. Efficacy and patterns of response and relapse

1989 • 682 citations

M-Vac (Methotrexate, Vinblastine, Doxorubicin and Cisplatin) for Advanced Transitional Cell Carcinoma of the Urothelium

1988 • 631 citations

Peroxisome Proliferator–Activated Receptor γ and Metabolic Disease

2001 • 581 citations

Peroxisome proliferator-activated receptors: insight into multiple cellular functions

2000 • 481 citations

Results of Contemporary Radical Cystectomy for Invasive Bladder Cancer: A Clinicopathological Study With an Emphasis on the Inadequacy of the Tumor, Nodes and Metastases Classification

1991 • 403 citations

Induction of differentiation and apoptosis by ligands of peroxisome proliferator-activated receptor gamma in non-small cell lung cancer.

2000 • 382 citations

Activation of PPARγ leads to inhibition of anchorage-independent growth of human colorectal cancer cells

1998 • 319 citations

Activation of PPARγ inhibits cell growth and induces apoptosis in human gastric cancer cells

1999 • 253 citations

Peroxisome proliferator-activated receptor-gamma: from adipogenesis to carcinogenesis

2001 • 231 citations

Combination Paclitaxel, Carboplatin, and Gemcitabine Is an Active Treatment for Advanced Urothelial Cancer

2001 • 213 citations

Phase I-II Study of Paclitaxel, Cisplatin, and Gemcitabine in Advanced Transitional-Cell Carcinoma of the Urothelium

2000 • 191 citations

Ligand type-specific Interactions of Peroxisome Proliferator-activated Receptor γ with Transcriptional Coactivators

2000 • 189 citations

Influence of J series prostaglandins on apoptosis and tumorigenesis of breast cancer cells

1999 • 183 citations

Troglitazone, a Peroxisome Proliferator-activated Receptor γ (PPARγ) Ligand, Selectively Induces the Early Growth Response-1 Gene Independently of PPARγ

2003 • 180 citations

Expression of Peroxisome Proferator-Activated Receptor γ (PPARγ) in Human Transitional Bladder Cancer and its Role in Inducing Cell Death

1999 • 175 citations

Peroxisome proliferator-activated receptor gamma agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor alpha in MCF-7 breast cancer cells.

2003 • 173 citations

Mutational analysis of the peroxisome proliferator-activated receptor gamma gene in human malignancies.

2001 • 143 citations

Prognostic factors for survival of patients with advanced urothelial tumors treated with methotrexate, vinblastine, doxorubicin, and cisplatin chemotherapy

1991 • 142 citations

A Novel Ring-Substituted Diindolylmethane,1,1-Bis[3′-(5-Methoxyindolyl)]-1-(p-t-Butylphenyl) Methane, Inhibits Extracellular Signal-Regulated Kinase Activation and Induces Apoptosis in Acute Myelogenous Leukemia

2005 • 124 citations

Differential Regulation of Vascular Endothelial Growth Factor Expression by Peroxisome Proliferator-activated Receptors in Bladder Cancer Cells

2002 • 115 citations

Peroxisome proliferator-activated receptor-γ upregulates caveolin-1 and caveolin-2 expression in human carcinoma cells

2003 • 105 citations

A new class of peroxisome proliferator-activated receptor gamma (PPARgamma) agonists that inhibit growth of breast cancer cells: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes.

2004 • 102 citations

15-Deoxy-Δ12,14-prostaglandin J2-induced apoptosis does not require PPARγ in breast cancer cells

2002 • 101 citations

Combining Radiation and Molecular Targeting in Cancer Therapy

2004 • 93 citations

Caveolin-Induced Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway Increases Arsenite Cytotoxicity

2003 • 92 citations

Role of Peroxisome Proliferator-Activated Receptor γ and Its Ligands in Non-Neoplastic and Neoplastic Human Urothelial Cells

2001 • 84 citations

2-Cyano-3,12-dioxoolean-1,9-dien-28-oic Acid and Related Compounds Inhibit Growth of Colon Cancer Cells through Peroxisome Proliferator-Activated Receptor γ-Dependent and -Independent Pathways

2005 • 81 citations

Peroxisome Proliferator-Activated Receptor γ-Dependent Activation of p21 in Panc-28 Pancreatic Cancer Cells Involves Sp1 and Sp4 Proteins

2004 • 78 citations

1,1-Bis(3′-indolyl)-1-( p -substitutedphenyl)methanes Induce Peroxisome Proliferator-Activated Receptor γ-Mediated Growth Inhibition, Transactivation, and Differentiation Markers in Colon Cancer Cells

2004 • 72 citations

Peroxisome Proliferator-activated Receptor γ-mediated Differentiation

2003 • 57 citations

A new class of peroxisome proliferator-activated receptor γ (PPARγ) agonists that inhibit growth of breast cancer cells: 1,1-Bis(3′-indolyl)-1-(p-substituted phenyl)methanes

2004 • 53 citations

Targeting peroxisome proliferator-activated receptors (PPARs) in kidney and urologic disease.

2002 • 41 citations

Translational regulation of cyclin D1 by 15-deoxy-delta(12,14)-prostaglandin J(2).

2002 • 34 citations

Contribution of caveolin-1α and Akt to TNF-α-induced cell death

2004 • 29 citations

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