Ectopic expression of IGF‐I and Shh by skeletal muscle inhibits disuse‐mediated skeletal muscle atrophy and bone osteopenia in vivo

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

2001 • 2,539 citations

High-efficiency gene transfer into skeletal muscle mediated by electric pulses

1999 • 901 citations

Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function

1998 • 700 citations

Atrophy of the soleus muscle by hindlimb unweighting

1990 • 632 citations

Spherical reflector as an electromagnetic-missile launcher

1990 • 310 citations

The anabolic activity of bone tissue, suppressed by disuse, is normalized by brief exposure to extremely low‐magnitude mechanical stimuli

2001 • 309 citations

Myostatin and the control of skeletal muscle mass

1999 • 269 citations

Extraosseous Blood Supply of the Tibia and the Effects of Different Plating Techniques: A Human Cadaveric Study

2002 • 259 citations

Rat hindlimb unloading: soleus histochemistry, ultrastructure, and electromyography

1990 • 227 citations

The response of bone to unloading

1999 • 216 citations

Control of somite patterning by Sonic hedgehog and its downstream signal response genes

1998 • 183 citations

Sonic Hedgehog induces proliferation of committed skeletal muscle cells in the chick limb

1998 • 179 citations

A new rat model simulating some aspects of space flight.

1979 • 165 citations

Targeted Expression of IGF‐1 Transgene to Skeletal Muscle Accelerates Muscle and Motor Neuron Regeneration

2002 • 140 citations

Myonuclear loss in atrophied soleus muscle fibers

1997 • 129 citations

Differentially expressed fibroblast growth factors regulate skeletal muscle development through autocrine and paracrine mechanisms.

1996 • 122 citations

Growth hormone/IGF-I and/or resistive exercise maintains myonuclear number in hindlimb unweighted muscles

1997 • 121 citations

Space Flight: A Challenge for Normal Bone Homeostasis

2001 • 120 citations

Future Human Bone Research in Space

1998 • 109 citations

Overexpression of IGF-I in skeletal muscle of transgenic mice does not prevent unloading-induced atrophy

1998 • 104 citations

Temporal and quantitative analysis of myogenic regulatory and growth factor gene expression in the developing mouse embryo

1992 • 78 citations

IGFs, Insulin, Shh, bFGF, and TGF-β1 Interact Synergistically to Promote Somite Myogenesis in Vitro

2000 • 73 citations

Expression Profiles of mRNAs for Osteoblast and Osteoclast Proteins as Indicators of Bone Loss in Mouse Immobilization Osteopenia Model

1999 • 72 citations

Subcutaneous administration of insulin-like growth factor (IGF)-II/IGF binding protein-2 complex stimulates bone formation and prevents loss of bone mineral density in a rat model of disuse osteoporosis

2002 • 69 citations

Soleus muscle nascent polypeptide chain elongation slows protein synthesis rate during non-weight-bearing activity

1994 • 62 citations

Body Fat Content Can Be Predicted In Vivo in Mice Using a Modified Dual-Energy X-Ray Absorptiometry Technique

2001 • 60 citations

High‐efficiency growth hormone releasing hormone plasmid vector administration into skeletal muscle mediated by electroporation in pigs

2003 • 55 citations

Twenty third annual Bowditch Lecture. Brain mechanisms for integration of growth hormones secretion.

1979 • 48 citations

Muscle-Based Gene Therapy and Tissue Engineering to Improve Bone Healing

2002 • 39 citations

Humeral bone density losses after shoulder surgery and immobilization

1996 • 37 citations

The effects of 10 days of spaceflight on the shuttle Endeavour on predominantly fast-twitch muscles in the rat

2000 • 34 citations

Effect of insulin-like growth factor-1 (IGF-1) plus alendronate on bone density during puberty in IGF-1-deficient MIDI mice

2002 • 33 citations

Growth Factor May Decrease Muscle Atrophy Secondary to Denervation

2001 • 25 citations

A simple hindlimb suspension apparatus.

1993 • 24 citations

Epitope-tagged insulin-like growth factor-I expression in muscle

2000 • 3 citations