Non-classical glutamate receptors, blocked by both NMDA and non-NMDA antagonists, stimulate nitric oxide production in neurons

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

1990 • 3,304 citations

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

1988 • 2,572 citations

Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes

1992 • 2,527 citations

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1991 • 2,371 citations

The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, and Distinct Properties in the Function of the Central Nervous System

1989 • 2,203 citations

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.

1991 • 2,173 citations

Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.

1989 • 1,850 citations

Excitatory amino acid neurotoxicity and neurodegenerative disease

1990 • 1,781 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

Limbic seizure and brain damage produced by kainic acid: Mechanisms and relevance to human temporal lobe epilepsy

1985 • 1,730 citations

A Family of AMPA-Selective Glutamate Receptors

1990 • 1,453 citations

A Requirement for the Intercellular Messenger Nitric Oxide in Long-Term Potentiation

1991 • 1,136 citations

Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger.

1991 • 1,016 citations

Molecular Cloning and Functional Expression of Glutamate Receptor Subunit Genes

1990 • 925 citations

Cloning of a novel glutamate receptor subunit, GluR5: Expression in the nervous system during development

1990 • 646 citations

Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA

1991 • 638 citations

Possible involvement of nitric oxide in long-term potentiation

1991 • 637 citations

The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits

1992 • 537 citations

Permeation of calcium through excitatory amino acid receptor channels in cultured rat hippocampal neurones.

1990 • 498 citations

The distribution of [3H]kainic acid binding sites in rat CNS as determined by autoradiography

1982 • 481 citations

The role of nitric oxide in hippocampal long-term potentiation

1992 • 470 citations

Cloning of a putative high-affinity kainate receptor expressed predominantly in hippocampal CA3 cells

1991 • 461 citations

Cloning of a putative glutamate receptor: A low affinity kainate-binding subunit

1992 • 379 citations

Excitatory amino acid receptors, second messengers and regulation of intracellular Ca2+ in mammalian neurons

1990 • 355 citations

NMDA receptor activation in rat hippocampus induces cyclic GMP formation through the l-arginine-nitric oxide pathway

1991 • 301 citations

Concanavalin A selectively reduces desensitization of mammalian neuronal quisqualate receptors.

1989 • 228 citations

Autoradiographic localization of high-affinity [3H]kainic acid binding sites in the rat forebrain

1983 • 227 citations

The ontogeny of excitatory amino acid receptors in the rat forebrain—II. Kainic acid receptors

1990 • 216 citations

Synaptogenesis of cultured striatal neurons in serum-free medium: a morphological and biochemical study.

1986 • 187 citations

A Kainate Receptor Linked to Nitric Oxide Synthesis from Arginine

1989 • 186 citations

A Role for Nitric Oxide in Long‐term Potentiation

1992 • 147 citations

Excitatory amino acid receptors coupled with guanylate cyclase in primary cultures of cerebellar granule cells

1987 • 146 citations

A Nitric Oxide Synthase Activity Selectively Stimulated by NMDA Receptors Depends on Protein Kinase C Activation in Mouse Striatal Neurons

1992 • 87 citations

Calcium directly permeates kainate/alpha-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid receptors in cultured cerebellar Purkinje neurons.

1992 • 70 citations

Release of Endogenous Amino Acids from Striatal Neurons in Primary Culture

1986 • 57 citations

Atrial natriuretic peptide effects on cGMP and cAMP contents in microdissected glomeruli and segments of the rat and rabbit nephrons

1987 • 49 citations

Further evidence for calcium permeability of non-NMDA receptor channels in hippocampal neurons

1992 • 25 citations

Establishment of a long-term primary culture of striatal neurons

1990 • 19 citations

On concanavalin A-treated striatal neurons quisqualate clearly behaves as a partial agonist of a receptor fully activated by kainate

1990 • 9 citations