Crystal structure of trp represser/operator complex at atomic resolution

The locus of sequence-directed and protein-induced DNA bending

1984 • 1,453 citations

The structure of an oligo(dA)·oligo(dT) tract and its biological implications

1987 • 975 citations

Sequence periodicities in chicken nucleosome core DNA

1986 • 930 citations

Structure of a B-DNA dodecamer

1981 • 891 citations

Computational crystallography

2012 • 705 citations

Bent helical structure in kinetoplast DNA

1982 • 595 citations

Crystallographic refinement of yeast aspartic acid transfer RNA

1985 • 498 citations

Biological Macromolecules and Assemblies

1987 • 400 citations

A hypothesis on a specific sequence-dependent conformation of DNA and its relation to the binding of the lac-repressor protein

1979 • 390 citations

Structure of the represser–operator complex of bacteriophage 434

1987 • 365 citations

MERLOT, an integrated package of computer programs for the determination of crystal structures by molecular replacement

1988 • 348 citations

The three-dimensional structure of trp repressor

1985 • 342 citations

On the specificity of DNA-protein interactions.

1986 • 308 citations

Kinked DNA in crystalline complex with EcoRI endonuclease

1984 • 303 citations

Structure refined to 2Å of a nicked DNA octanucleotide complex with DNase I

1988 • 293 citations

Unusual DNA Structures

2011 • 277 citations

The crystal structure of trp aporepressor at 1.8 Å shows how binding tryptophan enhances DNA affinity

1987 • 240 citations

Stabilities of nearest‐neighbor doublets in double‐helical DNA determined by fitting calculated melting profiles to observed profiles

1981 • 238 citations

Direct Evidence for DNA Bending at the Lambda Replication Origin

1987 • 233 citations

The integration host factor of Escherichia coli binds to bent DNA at the origin of replication of the plasmid pSC101

1987 • 228 citations

Gel retardation at low pH resolves trp repressor-DNA complexes for quantitative study.

1988 • 227 citations

Conformational change in the DNA associated with an unusual promoter mutation in a tRNA operon of Salmonella

1984 • 225 citations

Incorporation of fast Fourier transforms to speed restrained least-squares refinement of protein structures

1987 • 221 citations

Sequence-dependent variation in the conformation of DNA

1981 • 220 citations

An optimized potential function for the calculation of nucleic acid interaction energies I. Base stacking

1978 • 219 citations

Bent DNA at a yeast autonomously replicating sequence

1986 • 217 citations

A new least-squares refinement technique based on the fast Fourier transform algorithm

1978 • 193 citations

The bending of DNA in nucleosomes and its wider implications

1987 • 189 citations

Principles of sequence-dependent flexure of DNA

1986 • 164 citations

Biological Macromolecules and Assemblies

1985 • 163 citations

Sequence-specific positioning of core histones on an 860 base-pair DNA

1987 • 134 citations

Flexibility of the DNA‐binding domains of trp repressor

1988 • 133 citations

Mutational studies with the trp repressor of Escherichia coli support the helix-turn-helix model of repressor recognition of operator DNA.

1985 • 128 citations

The N-terminal arms of λ repressor wrap around the operator DNA

1982 • 118 citations

Solution structure of the Trp operator of Escherichia coli determined by NMR

1987 • 112 citations

Many gene-regulatory proteins appear to have a similar α-helical fold that binds DNA and evolved from a common precursor

1983 • 107 citations

Protein structure, folding and design

1985 • 93 citations

Escherichia coli tryptophan repressor binds multiple sites within the aroH and trp operators.

1987 • 93 citations

DNA specificity determinants of Escherichia coli tryptophan repressor binding.

1987 • 87 citations

Molecular basis of DNA sequence recognition by the catabolite gene activator protein: detailed inferences from three mutations that alter DNA sequence specificity.

1984 • 81 citations

The structural basis for the interaction between L-tryptophan and the Escherichia coli trp aporepressor.

1987 • 80 citations

Role of subunit interfaces in the allosteric mechanism of hemoglobin.

1976 • 71 citations

The structure of trp pseudorepressor at 1.65Å shows why indole propionate acts as a trp 'inducer'

1988 • 54 citations

Protein Structure, Folding and Design

1988 • 53 citations

Crystals of the trp repressor-operator complex suitable for X-ray diffraction analysis.

1987 • 30 citations

Base-Stacking Interactions in Double-Helical DNA Structures: Experiment Versus Theory

1984 • 27 citations

Biophysical Principles of Specificity and Stability of Protein-DNA Interactions: Application to RNA Polymerase (Eσ70)-Promoter Interactions

1988 • 4 citations