Hormonal and nonhormonal desensitization in isolated bone cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A simple efficient liquid scintillator for counting aqueous solutions in a liquid scintillation counter

1960 • 7,610 citations

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

A MICROCHEMICAL DETERMINATION OF DESOXYRIBONUCLEIC ACID

1952 • 921 citations

Calcium, Parathyroid Hormone and the Calcitonins

1973 • 397 citations

An effect of insulin on adipose-tissue adenosine 3′:5′-cyclic monophosphate phosphodiesterase

1970 • 346 citations

The Effect of Parathyroid Hormone on the Concentration of Adenosine 3',5'-Monophosphate in Skeletal Tissue in Vitro

1970 • 319 citations

Bone Cells: Biochemical and Biological Studies after Enzymatic Isolation

1964 • 283 citations

Rapid changes in rat pineal beta-adrenergic receptor: alterations in l-(3H)alprenolol binding and adenylate cyclase.

1975 • 265 citations

Hormone-stimulated desensitization of hormone-dependent adenylyl cyclase. Dual action of luteninizing hormone on pig graafian follicle membranes.

1976 • 244 citations

Cyclic adenosine monophosphate, CA++, and membranes.

1968 • 228 citations

Agonist-specific refractoriness induced by isoproterenol. Studies with mutant cells.

1976 • 219 citations

1,25-Dihydroxycholecalciferol and Parathormone: Effects on Isolated Osteoclast-Like and Osteoblast-Like Cells

1977 • 207 citations

Endocrinology of calcium metabolism

1979 • 194 citations

Stimulation and Desensitization of Macrophage Adenylate Cyclase by Prostaglandins and Catecholamines

1974 • 166 citations

Regulation of Adenosine 3′:5′-Cyclic Monophosphate Phosphodiesterase Activity in Fibroblasts by Intracellular Concentrations of Cyclic Adenosine Monophosphate

1972 • 141 citations

Role of beta-adrenergic receptors in catecholamine-induced desensitization of adenylate cyclase in human astrocytoma cells.

1978 • 130 citations

Regulation of adenylate cyclase-coupled beta adrenergic receptor binding sites by beta adrenergic catecholamines in vitro.

1976 • 119 citations

Desensitization of beta-adrenergic receptors by beta-adrenergic agonists in a cell-free system: resensitization by guanosine 5'-(beta, gamma-imino)triphosphate and other purine nucleotides.

1976 • 116 citations

Evidence for Preferential Effects of Parathyroid Hormone, Calcitonin and Adenosine on Bone and Periosteum¹

1977 • 114 citations

Regulation of adenosine 3':5'-monophosphate content of human astrocytoma cells: desensitization to catecholamines and prostaglandins.

1976 • 113 citations

Reversal of Catecholamine Refractoriness by Inhibitors of RNA and Protein Synthesis

1974 • 111 citations

Cyclic 3′5′ Adenosine Monophosphate in Isolated Bone Cells: Response to Low Concentrations of Parathyroid Hormone12 12

1973 • 106 citations

The Mode of Action of Dibutyryl Adenosine 3′,5′-Monophosphate on Bone Tissue in Vitro

1971 • 96 citations

Regulation of Phosphodiesterase Synthesis: Requirement for Cyclic Adenosine Monophosphate-Dependent Protein Kinase

1973 • 93 citations

Cyclic AMP-Mediated Induction of the Cyclic AMP Phosphodiesterase of C-6 Glioma Cells

1974 • 86 citations

Human synoviocytes: activation and desensitization by prostaglandins and 1-epinephrine.

1975 • 79 citations

An endogenous Ca2+-dependent activator protein of brain adenylate cyclase and cyclic neucleotide phosphodiesterase.

1978 • 77 citations

Cyclic nucleotides in bone and mineral metabolism.

1979 • 73 citations

Effects of Epinephrine, Adrenocorticotrophic Hormone, and Theophylline on Adenosine 3′,5′-Monophosphate Phosphodiesterase Activity in Fat Cells

1974 • 68 citations

Involvement of cyclic amp and protein synthesis in catecholamine refractoriness.

1978 • 67 citations

Adenosine 3′,5′-Monophosphate in Glial Tumor Cells

1973 • 66 citations

Altered adenosine cyclic 3',5'-monophosphate synthesis and degradation by C-6 astrocytoma cells following prolonged exposure to norepinephrine.

1976 • 65 citations

Cyclic 3′,5′-Adenosine Monophosphate in Isolated Bone Cells. II. Responses to Adenosine and Parathyroid Hormone¹

1974 • 65 citations

Desensitization of adenylate cyclase in cultured fibroblasts with prostaglandin E1 and epinephrine.

1979 • 59 citations

Isoproterenol-induced desensitization of adenylate cyclase responsiveness in a cell-free system.

1979 • 52 citations

Molecular mechanisms of activation and desensitization of adenylate cyclase coupled beta-adrenergic receptors.

1978 • 43 citations

Impaired Accumulation of Ribonucleic Acid Precursors and Depletion of Ribonucleic Acid in Glucocorticoid-treated Bone Cells

1969 • 41 citations

Cyclic AMP Production in Rat Calvariain Vitro: Interaction of Prostaglandins with Parathyroid Hormone

1977 • 39 citations

Induction of metabolic changes and down regulation of bovine parathyroid hormone-responsive adenylate cyclase are dissociable in isolated osteoclastic and osteoblastic bone cells.

1979 • 38 citations

Hormone-dependent desensitization of vasopressin-sensitive adenylate cyclase

1976 • 37 citations

Hormone-Specific Suppression of Adenosine 3′,5′-Monophosphate Responses in Bone in Vitro during Prolonged Incubation with Parathyroid Hormone, Prostaglandin E_1,and Calcitonin

1978 • 37 citations

Regulation of adenosine 3':5'-monophosphate content of human astrocytoma cells: mechanism of agonist-specific desensitization.

1976 • 35 citations

Parathyroid hormone-mediated refractoriness of rat kidney cyclic AMP system.

1979 • 32 citations

Regulation of Calcium Transport in Bone by Parathyroid Hormone

1971 • 31 citations

Anti-microtubular agents as inhibitors of desensitization to catecholamine stimulation of adenylate cyclase in Ehrlich ascites tumor cells

1979 • 30 citations

Acute suppression by PGF2 alpha on LH, epinephrine and fluoride stimulation of adenylate cyclase in rat luteal tissue.

1979 • 22 citations

Desensitization of prostaglandin-activated platelet adenylate cyclase

1979 • 22 citations

Separate genetic regulation of cyclic nucleotide phosphodiesterase and its protein activator in cultured mouse fibroblasts

1975 • 17 citations

Assay errors of cyclic 3′,5′-nucleotide phosphodiesterase activity based on the recovery of adenosine alone using an anionic-exchange resin column

1976 • 17 citations

PGE1-mediated cyclic AMP refractoriness: effects of cycloheximide and indomethacin.

1975 • 13 citations

On the accumulation of adenosine 3':5'-monophosphate in Ehrlich cells and adenylate cyclase desensitization in response to epinephrine.

1976 • 12 citations

Marked reduction of cyclic GMP phosphodiesterase activity in virally transformed mouse fibroblasts

1975 • 11 citations