Linear relationships between mitochondrial forces and cytoplasmic flows argue for the organized energy‐coupled nature of cellular metabolism

Methods of Enzymatic Analysis

1975 • 20,446 citations

HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS

1969 • 4,428 citations

Removal of Fatty Acids from Serum Albumin by Charcoal Treatment

1967 • 2,098 citations

COMPLEXES OF SEQUENTIAL METABOLIC ENZYMES

1987 • 1,019 citations

Biochemical systems analysis

1969 • 743 citations

Molecular Democracy: Who Shares the Controls?

1979 • 454 citations

Vectorial Chemistry and the Molecular Mechanics of Chemiosmotic Coupling: Power Transmission by Proticity

1976 • 431 citations

The value of ΔG° for the hydrolysis of ATP

1972 • 397 citations

Mitochondrial Hexokinase

1967 • 391 citations

Determination of the mitochondrial protonmotive force in isolated hepatocytes.

1980 • 263 citations

Fructose-1, 6-diphosphate Aldolase UV Assay, Manuel Method

1974 • 248 citations

Specificity in the Association of Glyceraldehyde 3-Phosphate Dehydrogenase with Isolated Human Erythrocyte Membranes

1973 • 242 citations

Binding of Aldolase and Triosephosphate Dehydrogenase to F‐Actin and Modification of Catalytic Properties of Aldolase

1970 • 197 citations

Interactions Between Soluble Enzymes and Subcellular Structur

1981 • 182 citations

Subcellular Metabolite Concentrations

1978 • 182 citations

Energy-linked nicotinamide nucleotide transhydrogenases

1977 • 176 citations

How enzymes can capture and transmit free energy from an oscillating electric field.

1986 • 164 citations

State of Oxidation-Reduction and State of Binding in the Cytosolic NADH-System as Disclosed by Equilibration with Extracellular Lactate/Pyruvate in Hemoglobin-Free Perfused Rat Liver

1972 • 163 citations

Non-equilibrium thermodynamics of energy conversion in bioenergetics

1979 • 162 citations

Control of the redox state of the nicotinamide–adenine dinucleotide couple in rat liver cytoplasm

1972 • 148 citations

Interaction of the aldolase and the membrane of human erythrocytes

1977 • 141 citations

A Quantitative Approach to Metabolic Control

1985 • 140 citations

The Thermodynamic Description of Enzyme-Catalyzed Reactions

1973 • 114 citations

Control of the rate of reverse electron transport in submitochondrial particles by the free energy

1977 • 101 citations

Changes in allosteric properties of phosphofructokinase bound to erythrocyte membranes.

1977 • 98 citations

Linear relation between rate and thermodynamic force in enzyme-catalyzed reactions

1980 • 96 citations

Organized Multienzyme Systems: Catalytic Properties

1985 • 95 citations

Evidence for energy-dependent change in phosphate binding for mitochondrial oxidative phosphorylation based on measurements of medium and intermediate phosphate-water exchanges.

1977 • 91 citations

Interrelations between fatty acid oxidation and the control of gluconeogenesis in perfused rat liver

1968 • 90 citations

The Calorigenic Nature of Hepatic Ketogenesis: An Explanation for the Stimulation of Respiration Induced by Fatty Acid Substrates

1983 • 83 citations

Regulation of the Redox State of the Pyridine Nucleotides in Rat Liver

1970 • 71 citations

Mitochondrial hexokinase of rat hepatoma cells in culture: solubilization and kinetic properties

1980 • 66 citations

Organization of enzymes of glycolysis and of glutathione metabolism in human red cell membranes

1975 • 56 citations

Association of Glyceraldehyde‐3‐Phosphate Dehydrogenase with the Particulate Fraction of Chicken Skeletal Muscle

1975 • 49 citations

Non-equilibrium thermodynamics of oxidative phosphorylation by inverted inner membrane vesicles of rat liver mitochondria.

1981 • 45 citations

Nonequilibrium linear behavior of biological systems. Existence of enzyme-mediated multidimensional inflection points

1980 • 45 citations

Transfer of reducing equivalents across the mitochondrial membrane I. Hydrogen transfer mechanisms involved in the reduction of pyruvate to lactate in isolated liver cells

1974 • 36 citations

An electrochemical interpretation of metabolism

1981 • 30 citations

Energy-dependent reduction of pyruvate to lactate by intact isolated parenchymal cells from rat liver

1971 • 26 citations

Energy‐dependent regulation of the steady‐state concentrations of the components of the lactate dehydrogenase reaction in liver

1980 • 21 citations

A Thermodynamic Treatment of Active Sodium Transport

1977 • 17 citations

Active transport: conditions for linearity and symmetry far from equilibrium.

1981 • 16 citations

Control of Enzyme Activity in Reversibly Adsorptive Enzyme Systems

1985 • 15 citations

Electron and Proton Flow in Hepatocytes During Fatty Acid and Pyruvate Oxidation: Implications for Energy Transduction and Heat Production

1986 • 2 citations