Gene Transfer of Endothelial Nitric Oxide Synthase Improves Relaxation of Carotid Arteries From Diabetic Rabbits

Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.

1996 • 2,456 citations

Impaired endothelium-dependent and independent vasodilation in patients with Type 2 (non-insulin-dependent) diabetes mellitus

1992 • 922 citations

Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine

1996 • 868 citations

Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene.

1995 • 783 citations

Superoxide Production in Vascular Smooth Muscle Contributes to Oxidative Stress and Impaired Relaxation in Atherosclerosis

1998 • 631 citations

Gene therapy inhibiting neointimal vascular lesion

1995 • 387 citations

Oxygen-derived free radicals, endothelium, and responsiveness of vascular smooth muscle

1986 • 380 citations

Impairment of endothelium‐dependent relaxation and changes in levels of cyclic GMP in aorta from streptozotocin‐induced diabetic rats

1989 • 294 citations

Superoxide dismutase recovers altered endothelium-dependent relaxation in diabetic rat aorta

1991 • 283 citations

DISFUNCTION OF VASCULAR ENDOTHELIUM IN DIABETES MELLITUS

1993 • 259 citations

Contraction of diabetic rabbit aorta caused by endothelium-derived PGH2-TxA2

1989 • 245 citations

Gene Therapy for Cardiovascular Disease

1995 • 229 citations

Enhanced, unaltered and impaired nitric oxide-mediated endothelium-dependent relaxation in experimental diabetes mellitus: importance of disease duration

1999 • 210 citations

Endothelial dysfunction in mesenteric resistance arteries of diabetic rats: role of free radicals

1994 • 198 citations

Oxygen free radicals abolish endothelium-dependent relaxation in diabetic rat aorta

1988 • 193 citations

Endothelium-Dependent Relaxation in Aorta of BB Rat

1987 • 151 citations

Possible superoxide radical-induced alteration of vascular reactivity in aortas from streptozotocin-treated rats.

1993 • 141 citations

Impaired Contraction and Endothelium-Dependent Relaxation in Isolated Resistance Vessels from Patients with Insulin-Dependent Diabetes Mellitus

1994 • 139 citations

Independent blockade of cerebral vasodilation from acetylcholine and nitric oxide

1988 • 119 citations

Expression and Function of Recombinant Endothelial Nitric Oxide Synthase Gene in Canine Basilar Artery

1997 • 112 citations

Gene Therapy for Cerebral Vascular Disease

1996 • 101 citations

Altered vascular function after adenovirus-mediated overexpression of endothelial nitric oxide synthase

1997 • 97 citations

Impaired endothelium‐dependent relaxation in isolated resistance arteries of spontaneously diabetic rats

1995 • 91 citations

Bioassay of endothelium-derived relaxing factor in diabetic rat aorta

1992 • 86 citations

In Vivo Gene Transfer of Nitric Oxide Synthase Enhances Vasomotor Function in Carotid Arteries From Normal and Cholesterol-Fed Rabbits

1998 • 84 citations

Expression and Function of Recombinant Endothelial Nitric Oxide Synthase Gene in Canine Basilar Artery After Experimental Subarachnoid Hemorrhage

1998 • 81 citations

Reversal by L-arginine of a dysfunctional arginine/nitric oxide pathway in the endothelium of the genetic diabetic BB rat

1997 • 77 citations

Intracellular trafficking of the muscarinic acetylcholine receptor: importance of subtype and cell type.

1996 • 77 citations

Improvement of Relaxation in an Atherosclerotic Artery by Gene Transfer of Endothelial Nitric Oxide Synthase

1998 • 75 citations

Adventitial Expression of Recombinant eNOS Gene Restores NO Production in Arteries Without Endothelium

1998 • 60 citations

Chronic Treatment In Vivo with Dimethylthiourea, a Hydroxyl Radical Scavenger, Prevents Diabetes-Induced Endothelial Dysfunction

1996 • 49 citations

Augmented Adenovirus-Mediated Gene Transfer to Atherosclerotic Vessels

1997 • 48 citations

Vascular action of the hypoglycaemic agent gliclazide in diabetic rabbits

1998 • 37 citations

Long‐term carbachol treatment‐induced down‐regulation of muscarinic M₂‐receptors but not m₂ receptor mRNA in a human lung cell line

1995 • 28 citations

Adenovirus-Mediated Gene Transfer Is Augmented in Basilar and Carotid Arteries of Heritable Hyperlipidemic Rabbits

1999 • 22 citations

Effects of buspirone on dopaminergic supersensitivity

1997 • 21 citations

Divergent actions of chronic insulin treatment in vivo versus acute treatment ex vivo on diabetic-induced endothelial dysfunction

1997 • 15 citations