Second Messengers: Sphingolipid signalling

Programmed Cell Death Induced by Ceramide

1993 • 1,779 citations

Functions of Sphingolipids and Sphingolipid Breakdown Products in Cellular Regulation

1989 • 1,251 citations

Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens

1993 • 879 citations

Ceramide activates heterotrimeric protein phosphatase 2A

1993 • 657 citations

Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway.

1994 • 459 citations

Intracellular Calcium Release Mediated by Sphingosine Derivatives Generated in Cells

1990 • 391 citations

Sphingolipid breakdown products: anti-proliferative and tumor-suppressor lipids

1993 • 281 citations

Tumor necrosis factor-alpha (TNF-alpha) signal transduction through ceramide. Dissociation of growth inhibitory effects of TNF-alpha from activation of nuclear factor-kappa B.

1993 • 217 citations

Renaturation and tumor necrosis factor-alpha stimulation of a 97-kDa ceramide-activated protein kinase.

1994 • 205 citations

Tumor necrosis factor activation of the sphingomyelin pathway signals nuclear factor kappa B translocation in intact HL-60 cells.

1993 • 179 citations

Sphingosine-1-phosphate, a metabolite of sphingosine, increases phosphatidic acid levels by phospholipase D activation

1992 • 154 citations

Ceramide: a novel second messenger

1992 • 137 citations

Sphingomyelinase and cell-permeable ceramide analogs stimulate cellular proliferation in quiescent Swiss 3T3 fibroblasts.

1992 • 128 citations

Substrate recognition by ceramide-activated protein kinase. Evidence that kinase activity is proline-directed.

1993 • 124 citations

Responses to sphingosine-1-phosphate in X. laevis oocytes: similarities with lysophosphatidic acid signaling

1993 • 94 citations

Retinoblastoma protein dephosphorylation induced by D-erythro-sphingosine.

1992 • 82 citations

Sphingolipids as mediators of effects of platelet-derived growth factor in vascular smooth muscle cells

1993 • 51 citations