Evolution of GITRL immune function: Murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily

The TNF and TNF Receptor Superfamilies

2001 • 3,533 citations

Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance

2002 • 1,745 citations

CD4+CD25+ Immunoregulatory T Cells

2002 • 1,434 citations

TNF/TNFR FAMILY MEMBERS IN COSTIMULATION OF T CELL RESPONSES

2004 • 1,320 citations

Calculation of Hydrodynamic Properties of Globular Proteins from Their Atomic-Level Structure

2000 • 1,035 citations

The molecular architecture of the TNF superfamily

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3D domain swapping: A mechanism for oligomer assembly

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The structure of tumor necrosis factor-alpha at 2.6 A resolution. Implications for receptor binding.

1989 • 511 citations

Engagement of Glucocorticoid-Induced TNFR Family-Related Receptor on Effector T Cells by its Ligand Mediates Resistance to Suppression by CD4+CD25+ T Cells

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The Structure of Tumor Necrosis Factor-α at 2.6 Å Resolution

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Human CD25+CD4+ T Suppressor Cell Clones Produce Transforming Growth Factor β, but not Interleukin 10, and Are Distinct from Type 1 T Regulatory Cells

2002 • 440 citations

Interactions of Tumor Necrosis Factor (TNF) and TNF Receptor Family Members in the Mouse and Human

2006 • 424 citations

A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis

1997 • 410 citations

Structural and Functional Analysis of the Costimulatory Receptor Programmed Death-1

2004 • 365 citations

Frontline: GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations

2004 • 358 citations

Structural basis for self-association and receptor recognition of human TRAF2

1999 • 355 citations

Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells

2003 • 353 citations

The Structural Basis for the Recognition of Diverse Receptor Sequences by TRAF2

1999 • 277 citations

The GITR–GITRL interaction: co-stimulation or contrasuppression of regulatory activity?

2006 • 276 citations

Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR

1999 • 191 citations

Identification of a Novel Activation-inducible Protein of the Tumor Necrosis Factor Receptor Superfamily and Its Ligand

1999 • 188 citations

GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily

2005 • 173 citations

GITR/GITRL: More than an effector T cell co‐stimulatory system

2007 • 134 citations

The Crystal Structure of the Costimulatory OX40-OX40L Complex

2006 • 131 citations

Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function

2007 • 65 citations

Glucocorticoid-Induced TNF Receptor, a Costimulatory Receptor on Naive and Activated T Cells, Uses TNF Receptor-Associated Factor 2 in a Novel Fashion as an Inhibitor of NF-κB Activation

2005 • 59 citations

Structural Basis of Inducible Costimulator Ligand Costimulatory Function: Determination of the Cell Surface Oligomeric State and Functional Mapping of the Receptor Binding Site of the Protein

2006 • 29 citations

1.8 Å structure of murine GITR ligand dimer expressed inDrosophila melanogasterS2 cells

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[Dr. Besim Omer Akalin and population policy in Turkey].

1999 • 3 citations