Stabilization of β-catenin impacts pancreas growth

Convergence of Wnt, ß-Catenin, and Cadherin Pathways

2004 • 2,451 citations

Insulin-promoter-factor 1 is required for pancreas development in mice

1994 • 1,789 citations

Wnt/β-Catenin Signaling in Mesenchymal Progenitors Controls Osteoblast and Chondrocyte Differentiation during Vertebrate Skeletogenesis

2005 • 1,536 citations

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

1996 • 1,505 citations

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

2002 • 1,500 citations

Intestinal polyposis in mice with a dominant stable mutation of the beta -catenin gene

1999 • 1,161 citations

An LDL-receptor-related protein mediates Wnt signalling in mice

2000 • 1,080 citations

Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog.

1996 • 829 citations

β-catenin: a key mediator of Wnt signaling

1998 • 746 citations

Dorsalizing signal Wnt-7a required for normal polarity of D–V and A–P axes of mouse limb

1995 • 719 citations

Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages

2000 • 653 citations

Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs

1994 • 624 citations

Links between signal transduction, transcription and adhesion in epithelial bud development

2003 • 564 citations

New aspects of Wnt signaling pathways in higher vertebrates

2001 • 550 citations

β-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system

2003 • 463 citations

Fgf10is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis

2001 • 452 citations

Regulation of pancreas development by hedgehog signaling

2000 • 415 citations

Intercellular signals regulating pancreas development and function

2001 • 399 citations

Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling

2002 • 353 citations

β-Catenin: A Pivot between Cell Adhesion and Wnt Signalling

2005 • 300 citations

Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung

2003 • 298 citations

β-Catenin is essential for pancreatic acinar but not islet development

2005 • 233 citations

β-Catenin and Hedgehog Signal Strength Can Specify Number and Location of Hair Follicles in Adult Epidermis without Recruitment of Bulge Stem Cells

2005 • 231 citations

Analysis of the Signaling Activities of Localization Mutants of β-Catenin during Axis Specification in Xenopus

1997 • 177 citations

Stabilization of β-catenin in the mouse zygote leads to premature epithelial-mesenchymal transition in the epiblast

2004 • 162 citations

Pancreas-Specific Deletion of β-Catenin Reveals Wnt-Dependent and Wnt-Independent Functions during Development

2005 • 160 citations

Attenuated Wnt Signaling Perturbs Pancreatic Growth but Not Pancreatic Function

2005 • 156 citations

Wnt/β-catenin signaling activates growth-control genes during overload-induced skeletal muscle hypertrophy

2005 • 147 citations

Activation of β-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation

2003 • 129 citations

Combined activities of hedgehog signaling inhibitors regulate pancreas development

2003 • 124 citations

Stabilization of β-catenin induces lesions reminiscent of prostatic intraepithelial neoplasia, but terminal squamous transdifferentiation of other secretory epithelia

2002 • 100 citations

Mosaic Cre-mediated recombination in pancreas using thepdx-1 enhancer/promoter

2000 • 100 citations

A Nuclear Function for Armadillo/β-Catenin

2004 • 94 citations

Expression of Wnt, Frizzled, sFRP, and DKK Genes in Adult Human Pancreas

2003 • 77 citations

Pancreas development in the chick embryo.

1997 • 61 citations

Matrix Metalloproteinases 2 and 9 Are Dispensable for Pancreatic Islet Formation and Function In Vivo

2005 • 40 citations