Synthesis and Biology of the Conformationally Restricted ACPD Analogue, 2-Aminobicyclo[2.1.1]hexane-2,5-dicarboxylic Acid-I, a Potent mGluR Agonist

<scp>CHARMM</scp>: A program for macromolecular energy, minimization, and dynamics calculations

1983 • 14,615 citations

Molecular Diversity of Glutamate Receptors and Implications for Brain Function

1992 • 2,535 citations

Excitatory amino acid neurotoxicity and neurodegenerative disease

1990 • 1,781 citations

N‐Acetylaspartylglutamate Selectively Activates mGluR3 Receptors in Transfected Cells

1997 • 295 citations

Multistep Carcinogenesis: a 1992 Perspective

1992 • 279 citations

Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1

1995 • 275 citations

3,5‐Dihydroxyphenylglycine Is a Highly Selective Agonist for Phosphoinositide‐Linked Metabotropic Glutamate Receptors in the Rat Hippocampus

1994 • 270 citations

Synthesis and Pharmacological Characterization of Aminocyclopentanetricarboxylic Acids: New Tools to Discriminate between Metabotropic Glutamate Receptor Subtypes

1997 • 142 citations

Photochemical reactions of simple alicyclic enones

1968 • 136 citations

Different coupling of excitatory amino acid receptors with Ca2+ channels in primary cultures of cerebellar granule cells

1985 • 110 citations

Atrial natriuretic peptides

1990 • 72 citations

A New Entry into 2-Azabicyclo[2.1.1]hexanes via 3-(Chloromethyl)cyclobutanone

1996 • 37 citations

Synthesis, molecular modeling, and biology of the 1-benzyl derivative of APDC-an apparent mGluR6 selective ligand

1997 • 37 citations

Definition of a pharmacophore for the metabotropic glutamate receptors negatively linked to adenylyl cyclase

1993 • 18 citations

Pretreatment of Cerebellar Granule Cells with Concanavalin A Potentiates Quisqualate‐Stimulated Phosphoinositide Hydrolysis

1991 • 16 citations

Synthesis of conformationally-constrained stereospecific analogs of glutamic acid as antagonists of metabotropic receptors

1995 • 14 citations