Expression of the glucose-regulated proteins (GRP94 and GRP78) in differentiated and undifferentiated mouse embryonic cells and the use of the GRP78 promoter as an expression system in embryonic cells

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

THE HEAT-SHOCK RESPONSE

1986 • 4,580 citations

A C-terminal signal prevents secretion of luminal ER proteins

1987 • 2,189 citations

Speculations on the functions of the major heat shock and glucose-regulated proteins

1986 • 1,574 citations

The induction of differentiation in teratocarcinoma stem cells by retinoic acid

1978 • 1,459 citations

An hsp70-like protein in the ER: Identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein

1986 • 1,457 citations

The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.

1982 • 1,371 citations

Expression of wild-type and mutant forms of influenza hemagglutinin: The role of folding in intracellular transport

1986 • 879 citations

Alkaline Phosphatase Activity in Mouse Teratoma

1973 • 630 citations

Coordinated regulation of a set of genes by glucose and calcium ionophores in mammalian cells

1987 • 442 citations

Biochemical characterization of the mammalian stress proteins and identification of two stress proteins as glucose- and Ca2+-ionophore-regulated proteins.

1983 • 431 citations

The relationship of N-linked glycosylation and heavy chain-binding protein association with the secretion of glycoproteins.

1987 • 357 citations

Negative regulation of viral enhancers in undifferentiated embryonic stem cells

1985 • 347 citations

A 90,000-dalton binding protein common to both steroid receptors and the Rous sarcoma virus transforming protein, pp60v-src.

1985 • 304 citations

ERp99, an abundant, conserved glycoprotein of the endoplasmic reticulum, is homologous to the 90-kDa heat shock protein (hsp90) and the 94-kDa glucose regulated protein (GRP94).

1987 • 294 citations

Endoplasmic reticulum contains a common, abundant calcium-binding glycoprotein, endoplasmin

1986 • 236 citations

Human Gene Encoding the 78,000-Dalton Glucose-Regulated Protein and Its Pseudogene: Structure, Conservation, and Regulation

1988 • 236 citations

Identity of the immunoglobulin heavy-chain-binding protein with the 78,000-dalton glucose-regulated protein and the role of posttranslational modifications in its binding function.

1988 • 211 citations

Altered expression of heat shock proteins in embryonal carcinoma and mouse early embryonic cells.

1984 • 173 citations

Biochemical characterization of the 94- and 78-kilodalton glucose-regulated proteins in hamster fibroblasts.

1984 • 148 citations

Calcium ionophore A23187 induces expression of glucose-regulated genes and their heterologous fusion genes.

1985 • 146 citations

Rat gene encoding the 78-kDa glucose-regulated protein GRP78: its regulatory sequences and the effect of protein glycosylation on its expression.

1987 • 144 citations

The response of cells to heat shock

1982 • 139 citations

Glucose-regulated protein (GRP94 and GRP78) genes share common regulatory domains and are coordinately regulated by common trans-acting factors.

1989 • 130 citations

Fertilization of mammalian eggs by sperm injection

1983 • 128 citations

Transcriptional regulation of two genes specifically induced by glucose starvation in a hamster mutant fibroblast cell line.

1983 • 128 citations

The accumulation of three specific proteins related to glucose‐regulated proteins in a temperature‐sensitive hamster mutant cell line K12

1981 • 125 citations

Quantitative aspects of RNA synthesis and polyadenylation in 1-cell and 2-cell mouse embryos

1983 • 104 citations

The nucleotide sequence encoding the hamster 78-kDa glucose-regulated protein (GRP78) and its conservation between hamster and rat

1987 • 93 citations

Enhanced transcription of the 78,000-dalton glucose-regulated protein (GRP78) gene and association of GRP78 with immunoglobulin light chains in a nonsecreting B-cell myeloma line (NS-1).

1989 • 54 citations

A calcium ionophore-inducible cellular promoter is highly active and has enhancerlike properties.

1986 • 51 citations

The organization of the rat GRP78 gene and A23187-induced expression of fusion gene products targeted intracellularly

1988 • 32 citations

Increased expression of the glucose-regulated gene encoding the Mr 78,000 glucose-regulated protein in chemically and radiation-transformed C3H 10T1/2 mouse embryo cells.

1987 • 31 citations

The effect of extracellular Ca2+ and temperature on the induction of the heat-shock and glucose-regulated proteins in hamster fibroblasts

1986 • 29 citations

Murine A type retroviruses promote high levels of gene expression in embryonal carcinoma cells

1988 • 17 citations

Cooperative interactions between the GRP78 enhancer and promoter elements in hamster fibroblasts

1989 • 11 citations

Negative transcriptional regulatory element that functions in embryonal carcinoma cells.

1989 • 7 citations