The Role of Adhesion Molecules in Epithelial–T-Cell Interactions in Thymus and Skin

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1).

1986 • 2,490 citations

Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1)

1987 • 1,712 citations

A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1.

1986 • 1,428 citations

LEUKOCYTE ADHESION DEFICIENCY: An Inherited Defect in the Mac-1, LFA-1, and p150,95 Glycoproteins

1987 • 1,147 citations

The major human rhinovirus receptor is ICAM-1

1989 • 1,134 citations

An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein

1984 • 1,132 citations

The Lymphocyte Function Associated LFA-1, CD2, and LFA-3 Molecules: Cell Adhesion Receptors of the Immune System

1987 • 1,104 citations

Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells.

1988 • 988 citations

Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families

1988 • 967 citations

Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure.

1987 • 949 citations

A cell adhesion molecule, ICAM-1, is the major surface receptor for rhinoviruses

1989 • 825 citations

Immunologic Functions of Ia-Bearing Epidermal Langerhans Cells

1978 • 732 citations

Intercellular adhesion molecule-1 is an endothelial cell adhesion receptor for Plasmodium falciparum

1989 • 703 citations

An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2

1987 • 699 citations

Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by interferon gamma and is mediated by intercellular adhesion molecule 1 (ICAM-1).

1988 • 680 citations

Correlation of specific keratins with different types of epithelial differentiation: Monoclonal antibody studies

1982 • 666 citations

Expression of the γ-δ T-cell receptor on intestinal CD8+ intraepithelial lymphocytes

1988 • 663 citations

Human lymphocytes bearing T cell receptor gamma/delta are phenotypically diverse and evenly distributed throughout the lymphoid system.

1989 • 547 citations

Developmentally ordered appearance of thymocytes expressing different T-cell antigen receptors

1988 • 540 citations

The Sézary syndrome: a malignant proliferation of helper T cells.

1976 • 485 citations

Identification of a human T lymphocyte surface protein associated with the E-rosette receptor.

1981 • 419 citations

Cotransfection of ICAM-1 and HLA-DR reconstitutes human antigen-presenting cell function in mouse L cells

1989 • 389 citations

Recombinant Gamma Interferon Induces HLA-DR Expression on Cultured Human Keratinocytes

1984 • 351 citations

Adhesive protein receptors on hematopoietic cells

1988 • 350 citations

The effect of thymus environment on T cell development and tolerance

1988 • 330 citations

H-2 antigens of the thymus determinelymphocyte specificity

1978 • 321 citations

Development and Function of Subpopulations of Thymocytes and T Lymphocytes

2015 • 296 citations

Thymus and Lymphohemopoietic Cells: Their Role in T Cell Maturation in Selection of T Cells' H‐2‐Restriction‐Specificity and in H‐2 Linked Ir Gene Control

1978 • 291 citations

Graft-versus-host disease induces expression of Ia antigen in rat epidermal cells and gut epithelium

1981 • 284 citations

A human T lymphocyte differentiation marker defined by monoclonal antibodies that block E-rosette formation.

1981 • 281 citations

LFA-1 and other accessory molecules functioning in adhesions of T and B lymphocytes

1987 • 223 citations

Anchoring mechanisms for LFA-3 cell adhesion glycoprotein at membrane surface

1987 • 220 citations

Regulation of T-cell receptor γ-chain RNA expression in murine Thy-1+ dendritic epidermal cells

1987 • 213 citations

Thymocyte binding to human thymic epithelial cells is inhibited by monoclonal antibodies to CD-2 and LFA-3 antigens.

1987 • 213 citations

Lymphocyte Traffic, T-Cell Malignancies and the Skin

1978 • 197 citations

The Human Thymic Microenvironment

1984 • 184 citations

Leukocyte function-associated antigen 1 is an activation molecule for human T cells.

1989 • 177 citations

Development and Function of Subpopulations of Thymocytes and T Lymphocytes (Part 1 of 2)

1975 • 168 citations

Limited diversity of T-cell receptor gamma-chain expression of murine Thy-1+ dendritic epidermal cells revealed by V gamma 3-specific monoclonal antibody.

1989 • 151 citations

Current Status of Thymosin and Other Hormones of the Thymus Gland

1981 • 151 citations

The structure of the human CD2 gene and its expression in transgenic mice.

1988 • 150 citations

T cell adhesion molecules

1988 • 145 citations

Human thymic epithelial cells produce interleukin 1.

1987 • 136 citations

The CD2 ligand LFA-3 activates T cells but depends on the expression and function of the antigen receptor.

1988 • 131 citations

STUDIES OF THE ROLE OF THE THYMIC ENVIRONMENT IN THE INDUCTION OF TOLERANCE TO MHC ANTIGENS

1985 • 127 citations

Expression of HLA-DR (Ia like) antigen on epidermal keratinocytes in human dermatoses.

1984 • 113 citations

Thy-1+ dendritic epidermal cells belong to the T-cell lineage.

1987 • 111 citations

Thymic cortical epithelial cells can present self-antigens in vivo

1989 • 108 citations

Histologic Diagnosis of Inflammatory Skin Diseases: A Method by Pattern Analysis

1978 • 107 citations

Human thymic epithelial cells produce granulocyte and macrophage colony-stimulating factors.

1988 • 97 citations

Thymocyte LFA-1 and thymic epithelial cell ICAM-1 molecules mediate binding of activated human thymocytes to thymic epithelial cells.

1990 • 92 citations

Induction of Lymphocyte Differentiation by Epidermal Cultures

1981 • 89 citations

Markedly Diminished Epidermal Keratinocyte Expression of Intercellular Adhesion Molecule-1 (ICAM-1) in Sézary Syndrome

1989 • 86 citations

Monoclonal antibodies to CD2 and lymphocyte function-associated antigen 3 inhibit human thymic epithelial cell-dependent mature thymocyte activation.

1987 • 84 citations

Epidermal expression of HLA-DR antigens in mycosis fungoides

1978 • 84 citations

Thymopoietin-like Substance in Human Skin

1983 • 83 citations

Presentation of antigen, foreign major histocompatibility complex proteins and self by thymus cortical epithelium

1989 • 83 citations

Induction of MHC-restricted specificity and tolerance in the thymus

1986 • 82 citations

A 19-kDa human erythrocyte molecule H19 is involved in rosettes, present on nucleated cells, and required for T cell activation. Comparison of the roles of H19 and LFA-3 molecules in T cell activation.

1989 • 77 citations

Human thymic epithelial cells function as accessory cells for autologous mature thymocyte activation.

1987 • 70 citations

Human thymocytes bind to autologous and allogeneic thymic epithelial cells in vitro.

1986 • 59 citations

T lymphocytes and monocytes bind to keratinocytes in frozen sections of biopsy specimens of normal skin treated with gamma interferon

1989 • 51 citations

Cell-mediated immunity in cutaneous disease

1986 • 51 citations

A MALIGNANT PROLIFERATION OF HELPER T CELLS

1976 • 50 citations

Purified lymphocyte function-associated antigen-3 (LFA-3) activates human thymocytes via the CD2 pathway.

1988 • 50 citations

Locally administered monoclonal antibodies to lymphocyte function-associated antigen 1 and to L3T4 prevent cutaneous graft-vs-host disease.

1988 • 43 citations

Cloning of human thymic subcapsular cortex epithelial cells with T-lymphocyte binding sites and hemopoietic growth factor activity.

1987 • 39 citations

A unique epitope on the CD2 molecule defined by the monoclonal antibody 9-1: epitope-specific modulation of the E-rosette receptor and effects on T-cell functions

1986 • 36 citations

Thymotaxin: a thymic epithelial peptide chemotactic for T-cell precursors.

1988 • 34 citations

Phorbol Ester Treatment Enhances Binding of Mononuclear Leukocytes to Autologous and Allogeneic Gamma-Interferon-Treated Keratinocytes, Which are Blocked by Anti-LFA-1 Monoclonal Antibody

1988 • 26 citations

[The Sézary syndrome].

1979 • 12 citations