Rapid method for detection of point mutations using mismatch binding protein (MutS) and an optical biosensor

Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms.

1989 • 3,707 citations

Quantitative determination of surface concentration of protein with surface plasmon resonance using radiolabeled proteins

1991 • 1,037 citations

DNA fragments differing by single base-pair substitutions are separated in denaturing gradient gels: correspondence with melting theory.

1983 • 895 citations

Mispair specificity of methyl-directed DNA mismatch correction in vitro.

1988 • 341 citations

Isolation and Characterization of the Escherichia coli mutL Gene Product

1989 • 298 citations

Methyl-directed DNA Mismatch Correction

1989 • 297 citations

Mismatch Binding Protein-Based Mutation Detection Systems

1995 • 111 citations

Mismatch-containing oligonucleotide duplexes bound by theE.coli mutS-encoded protein

1988 • 90 citations

A New Approach to Determine the Effect of Mismatches on Kinetic Parameters in DNA Hybridization Using an Optical Biosensor

1995 • 87 citations

Mutation detection by mismatch binding protein, MutS, in amplified DNA: application to the cystic fibrosis gene.

1994 • 61 citations

MutS binding protects heteroduplex DNA from exonuclease digestionin vitro: a simple method for detecting mutations

1994 • 52 citations