Clomethiazole Acute Stroke Study (CLASS)

Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS)

1995 • 3,456 citations

Classification and natural history of clinically identifiable subtypes of cerebral infarction

1991 • 3,237 citations

Intravenous Thrombolysis With Recombinant Tissue Plasminogen Activator for Acute Hemispheric Stroke

1995 • 2,209 citations

Enlargement of human cerebral ischemic lesion volumes measured by diffusion‐weighted magnetic resonance imaging

1997 • 578 citations

Progressive Derangement of Periinfarct Viable Tissue in Ischemic Stroke

1992 • 423 citations

Prolonged Persistence of Substantial Volumes of Potentially Viable Brain Tissue After Stroke

1996 • 318 citations

Interim Analyses in Randomized Clinical Trials: Ramifications and Guidelines for Practitioners

1987 • 200 citations

Multicenter trial of hemodilution in acute ischemic stroke. I. Results in the total patient population. Scandinavian Stroke Study Group.

1987 • 190 citations

Neuroprotective activity of chlormethiazole following transient forebrain ischaemia in the gerbil

1991 • 114 citations

Comparison of clinical and neuroradiological findings in first-ever stroke. A population-based study.

1994 • 107 citations

The effects of chlormethiazole and nimodipine on cortical infarct area after focal cerebral ischaemia in the rat

1993 • 81 citations

The modulation by chlormethiazole of the GABA_A‐receptor complex in rat brain

1989 • 78 citations

The neuroprotective effect of chlormethiazole on ischaemic neuronal damage following permanent middle cerebral artery ischaemia in the rat

1995 • 69 citations

The effect of chlormethiazole on neuronal damage in a model of transient focal ischaemia

1995 • 64 citations

Modulation of GABAA and glycine receptors by chlormethiazole

1992 • 56 citations

The protective action of chlormethiazole against ischaemia‐induced neurodegeneration in gerbils when infused at doses having little sedative or anticonvulsant activity

1995 • 49 citations

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