AMD3100, a CxCR4 Antagonist, Attenuates Allergic Lung Inflammation and Airway Hyperreactivity

Human Chemokines: An Update

1997 • 2,235 citations

Flexible Programs of Chemokine Receptor Expression on Human Polarized T Helper 1 and 2 Lymphocytes

1998 • 1,574 citations

A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

1996 • 1,482 citations

The Chemokine SDF-1 Is a Chemoattractant for Human CD34+ Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34+ Progenitors to Peripheral Blood

1997 • 1,414 citations

T cells and eosinophils in the pathogenesis of asthma

1992 • 585 citations

Inhibition of T-tropic HIV Strains by Selective Antagonization of the Chemokine Receptor CXCR4

1997 • 556 citations

The Coordinated Action of CC Chemokines in the Lung Orchestrates Allergic Inflammation and Airway Hyperresponsiveness

1998 • 546 citations

Pharmacokinetics and Safety of AMD-3100, a Novel Antagonist of the CXCR-4 Chemokine Receptor, in Human Volunteers

2000 • 504 citations

Recent Advances in Chemokines and Chemokine Receptors

1999 • 414 citations

The chemokine receptor CCR8 is preferentially expressed in Th2 but not Th1 cells.

1998 • 409 citations

Mast Cells Can Amplify Airway Reactivity and Features of Chronic Inflammation in an Asthma Model in Mice

2000 • 400 citations

Switch in chemokine receptor expression upon TCR stimulation reveals novel homing potential for recently activated T cells

1999 • 367 citations

Chemokines: signal lamps for trafficking of T and B cells for development and effector function

1999 • 348 citations

Cutting Edge: The Chemokine Receptor CCR8 Is Preferentially Expressed in Th2 But Not Th1 Cells

1998 • 341 citations

Modulation of Airway Inflammation by Passive Transfer of Allergen-Specific Th1 and Th2 Cells in a Mouse Model of Asthma

1999 • 273 citations

Mouse Monocyte-Derived Chemokine Is Involved in Airway Hyperreactivity and Lung Inflammation

1999 • 256 citations

AMD3100, a Potent and Specific Antagonist of the Stromal Cell-Derived Factor-1 Chemokine Receptor CXCR4, Inhibits Autoimmune Joint Inflammation in IFN-γ Receptor-Deficient Mice

2001 • 253 citations

Efficient Interaction of HIV-1 with Purified Dendritic Cells via Multiple Chemokine Coreceptors

1996 • 245 citations

Epithelial cells as regulators of airway inflammation

1998 • 234 citations

Bicyclams, a class of potent anti-HIV agents, are targeted at the HIV coreceptor Fusin/CXCR-4

1997 • 226 citations

Aberrant in Vivo T Helper Type 2 Cell Response and Impaired Eosinophil Recruitment in Cc Chemokine Receptor 8 Knockout Mice

2001 • 215 citations

Monocyte Chemoattractant Protein-1 Mediates Cockroach Allergen-Induced Bronchial Hyperreactivity in Normal But Not CCR2−/− Mice: The Role of Mast Cells

1999 • 210 citations

Mucosal IFN-gamma gene transfer inhibits pulmonary allergic responses in mice.

1996 • 207 citations

Critical Involvement of the Chemotactic Axis CXCR4/Stromal Cell-Derived Factor-1α in the Inflammatory Component of Allergic Airway Disease

2000 • 193 citations

Functional expression of the CXC-chemokine receptor-4/fusin on mouse microglial cells and astrocytes.

1997 • 182 citations

Assessment of chemokine receptor expression by human Th1 and Th2 cells in vitro and in vivo

1999 • 179 citations

Differential recruitment of leukocyte populations and alteration of airway hyperreactivity by C-C family chemokines in allergic airway inflammation.

1997 • 177 citations

IL-4 induces functional cell-surface expression of CXCR4 on human T cells.

1998 • 169 citations

Temporal Role of Chemokines in a Murine Model of Cockroach Allergen-Induced Airway Hyperreactivity and Eosinophilia

1998 • 156 citations

Enhanced Pulmonary Allergic Responses toAspergillusin CCR2−/− Mice

2000 • 150 citations

Effects of inhaled budesonide on allergen-induced airway responses and airway inflammation.

1996 • 150 citations

A Sensitive Elisa for the Detection of Human Monocyte Chemoattractant Protein-1 (MCP-1)

1992 • 142 citations

Cutting Edge: IL-4 Induces Functional Cell-Surface Expression of CXCR4 on Human T Cells

1998 • 139 citations

The CC chemokine antagonist Met‐RANTES inhibits eosinophil effector functions through the chemokine receptors CCR1 and CCR3

1997 • 130 citations

Expression of CXCR4 in Eosinophils: Functional Analyses and Cytokine-Mediated Regulation

2000 • 130 citations

Chemokines and asthma: redundancy of function or a coordinated effort?

1999 • 117 citations

Mucosal IL-12 gene delivery inhibits allergic airways disease and restores local antiviral immunity

1998 • 117 citations

Cytokines and Cell Surface Molecules Independently Induce CXCR4 Expression on CD4+ CCR7+ Human Memory T Cells

2000 • 115 citations

Th1 and Th2 CD4+ Cells in the Pathogenesis of Allergic Diseases

1997 • 100 citations

The effect of treatment with oral corticosteroids on asthma symptoms and airway inflammation.

1997 • 100 citations

A chemokine, SDF-1/PBSF, and its receptor, CXC chemokine receptor 4, as mediators of hematopoiesis.

2000 • 99 citations

IL-4 and a glucocorticoid up-regulate CXCR4 expression on human CD4+ T lymphocytes and enhance HIV-1 replication

1998 • 97 citations

Lymphocyte Responses to Chemokines

1998 • 93 citations

Differential Roles of IL-18 in Allergic Airway Disease: Induction of Eotaxin by Resident Cell Populations Exacerbates Eosinophil Accumulation

2000 • 79 citations

Stem Cell Factor-Induced Airway Hyperreactivity in Allergic and Normal Mice

1999 • 54 citations

Administration of Interleukin‐12 Prevents Mite Der p 1 Allergen‐IgE Antibody Production and Airway Eosinophil Infiltration in an Animal Model of Airway Inflammation

1999 • 52 citations

Role of the Heterotrimeric G Proteins in Stromal-Derived Factor-1α-Induced Natural Killer Cell Chemotaxis and Calcium Mobilization

1997 • 49 citations

Chemokine receptors and their role in leukocyte activation

1999 • 43 citations

Hospitalization patterns in severe acute asthma in children

1997 • 42 citations

Chemokine stromal cell–derived factor 1α activates basophils by means of CXCR4

2000 • 35 citations

Observations on asthma.

1995 • 35 citations

Relative effects of inhaled corticosteroids on immunopathology and physiology in asthma: a controlled study.

1996 • 32 citations

The Pathobiology of Eosinophilic Inflammation

1997 • 31 citations

Genetics of Asthma: A Review

1997 • 28 citations

Specific Elisas for the Detection of Human Macrophage Inflammatory Protein-1 Alpha and Beta

1993 • 24 citations

Wang, J. et al. IL-4 and a glucocorticoid up-regulate CXCR4 expression on human CD4+ T lymphocytes and enhance HIV-1 replication. J. Leukoc. Biol. 64, 642−649

1998 • 17 citations

Inhaled beclomethasone dipropionate downregulates CD4 and CD8 T-lymphocyte activation in peripheral blood of patients with asthma

1997 • 16 citations

Allergen-Induced Changes in Bone Marrow Progenitors and Airway Responsiveness in Dogs

1995 • 9 citations