Use and abuse of benzodiazepines. Issues relevant to prescribing.

Insomnia and Its Treatment

1985 • 1,069 citations

Communication, compliance, and concordance between physicians and patients with prescribed medications.

1976 • 440 citations

Withdrawal Reaction after Long-Term Therapeutic Use of Benzodiazepines

1986 • 371 citations

Withdrawal reactions from chlordiazepoxide (?Librium?)

1961 • 340 citations

National Patterns of Psychotherapeutic Drug Use

1973 • 336 citations

Abuse liability of benzodiazepines.

1987 • 313 citations

Insomnia and its treatment

1984 • 301 citations

BENZODIAZEPINE WITHDRAWAL SYMPTOMS AND PROPRANOLOL

1981 • 298 citations

Benzodiazepine Dependence A Review of the Evidence

1983 • 288 citations

GRADUAL WITHDRAWAL OF DIAZEPAM AFTER LONG-TERM THERAPY

1983 • 270 citations

Long-term Diazepam Therapy and Clinical Outcome

1983 • 261 citations

Prevalence and Correlates of the Long-term Regular Use of Anxiolytics

1984 • 228 citations

Drug preference and mood in humans: Diazepam

1980 • 212 citations

Rebound Insomnia and Rebound Anxiety: A Review

1983 • 198 citations

Chronic use of benzodiazepines and psychomotor and cognitive test performance

1986 • 186 citations

Rebound anxiety in anxious patients after abrupt withdrawal of benzodiazepine treatment

1984 • 178 citations

BENZODIAZEPINES: USE, OVERUSE, MISUSE, ABUSE?

1973 • 167 citations

LENGTH OF TREATMENT WITH ANXIOLYTIC SEDATIVES AND RESPONSE TO THEIR SUDDEN WITHDRAWAL

1973 • 163 citations

A cross-national comparison of anti-anxiety/sedative drug use

1984 • 158 citations

Early Morning Insomnia with Rapidly Eliminated Benzodiazepines

1983 • 139 citations

Benzodiazepine Withdrawal Phenomena

1981 • 133 citations

Drug preference in humans: double-blind choice comparison of pentobarbital, diazepam and placebo.

1980 • 116 citations

Low-dose dependence in chronic benzodiazepine users: a preliminary report on 119 patients.

1986 • 102 citations

Human drug self-administration: double-blind comparison of pentobarbital, diazepam, chlorpromazine and placebo.

1979 • 98 citations

Precipitated diazepam withdrawal in baboons: Effects of dose and duration of diazepam exposure

1984 • 95 citations

‘Tonic’, ‘fuel’ and ‘food’: Social and symbolic aspects of the long-term use of psychotropic drugs

1981 • 93 citations

Diazepam metabolism in normal man. II. Serum concentration and clinical effect after oral administration and cumulation.

1974 • 92 citations

Opiates as Reinforcing Stimuli

1971 • 91 citations

Comparison of diazepam and oxazepam: preference, liking and extent of abuse.

1984 • 88 citations

Controlled study of withdrawal symptoms and rebound anxiety after six week course of diazepam for generalised anxiety.

1985 • 80 citations

Comparative Effectiveness of Nine Hypnotic Drugs: Sleep Laboratory Studies

1977 • 79 citations

Effects of combined alcohol and benzodiazepine: A review

1984 • 75 citations

Lack of Preference for Diazepam in Anxious Volunteers

1986 • 70 citations

A longitudinal study of psychotropic drug prescription

1982 • 69 citations

Addiction to Diazepam

1976 • 68 citations

Comparison of short and long half-life benzodiazepine hypnotics: Triazolam and quazepam

1986 • 67 citations

Barbiturate-reinforced responding in rhesus monkeys: comparisons of drugs with different durations of action.

1975 • 66 citations

Quazepam and flurazepam: Long-term use and extended withdrawal

1982 • 63 citations

Correlates of Compliance with Psychoactive Prescriptions

1984 • 62 citations

DIAZEPAM IN NEWLY ADMITTED SCHIZOPHRENICS.

1963 • 61 citations

Long-term Use of Diazepam

1981 • 52 citations

Dependence on Tranquillizers

1984 • 50 citations

Safety and Efficacy of Long-term Diazepam Therapy

1980 • 45 citations

Diazepam on Demand

1974 • 44 citations

Reinforcing properties of clonidine in rhesus monkeys

1982 • 43 citations

Diazepam withdrawal syndrome: its prolonged and changing nature.

1982 • 41 citations

Drug Abuse Among Alcoholic Women

1979 • 40 citations

Use of Tranquilizing Drugs by a Middle-Aged Population in a West German City

1977 • 33 citations

A controlled trial of diazepam withdrawal in chronically anxious outpatients

1982 • 32 citations

Lack of preference for flurazepam in normal volunteers

1984 • 32 citations

Tolerance and dependence after chronic administration of clonidine to the rat

1977 • 32 citations

Dose-response studies of quazepam

1981 • 27 citations

Social effects of diazepam use: A longitudinal field study

1985 • 26 citations

Is the Use of Hypnotics, Sedatives and Minor Tranquillizers Really a Major Health Problem?

1976 • 25 citations

Purchases of hypnotics, sedatives and minor tranquillizers anong 2,566 individuals in the country of Jämtland, Sweden

1977 • 25 citations

The risk of pharmacological dependence with buspirone.

1985 • 24 citations

Health and social characteristics of long-term psychotropic drug takers

1982 • 20 citations

CLINICAL EXPERIENCE WITH PIPOTIAZINE PALMITATE (19.552 R.P.) IN NORDIC COUNTRIES: Report of a multicentre investigation

1973 • 19 citations

The use of tranquilizers in the treatment of mixed drug abuse.

1975 • 17 citations

General Practitioners' Indications for Psychotropic Drugs

1974 • 17 citations

Principles of Therapeutic Applications of Benzodiazepines

1985 • 16 citations

Utilization of Psychotropic Drugs in Office-Based Ambulatory Care: National Ambulatory Medical Care Survey, 1980 and 1981

1983 • 16 citations

Benzodiazepine dependence: a general practice survey.

1981 • 16 citations

Methylphenidate (ritalin) abuse and methadone maintenance.

1975 • 15 citations

Long-Term Treatment with Diazepam

1981 • 13 citations

Benzodiazepines in Emotional Disorders

1983 • 12 citations

CHLORDIAZEPOXIDE: LONG‐TERM USE IN ALCOHOLISM

1976 • 12 citations

Use of Sedatives and Hypnotics Prescribed in a Family Practice

1984 • 11 citations

The dependence potential of benzodiazepines

1984 • 11 citations

Experimental Abuse Liability Assessment of Benzodiazepines

1983 • 9 citations

Use of Stimulant/Depressant Drugs by Drug Abuse Clients in Selected Metropolitan Areas

1981 • 9 citations

Prescribing for alcoholics. A survey of drugs taken prior to admission to an alcoholism unit.

1985 • 7 citations

A survey of diazepam patients.

1986 • 7 citations

Treatment of triazolam dependence with a tapering withdrawal regimen.

1986 • 7 citations

Drug Abuse and Dependence in Psychiatric Inpatients

1985 • 7 citations

Psychopharmacologic agents: Prescription patterns of non-psychiatrists

1977 • 6 citations

Book ReviewFood Constituents Affecting Normal and Abnormal Behaviors

1986 • 5 citations

Primary drug abuse among women: A national study

1981 • 5 citations

Neighborhood Health Center Patients who use Minor Tranquilizers

1979 • 4 citations

Neuroendocrine correlates of clinical response during withdrawal from chlordiazepoxide.

1978 • 3 citations

Management of benzodiazepine dependence.

1986 • 3 citations

Experimental induction of benzodiazepine physical dependence in rodents.

1982 • 3 citations