Alterations in the neural growth hormone axis following hypoxic–ischemic brain injury

Leptin enters the brain by a saturable system independent of insulin

1996 • 1,210 citations

Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons

1995 • 629 citations

Essential Role of Growth Hormone in Ischemia-Induced Retinal Neovascularization

1997 • 394 citations

Radioimmunoassays for IGFs and IGFBPs.

1994 • 367 citations

Insulin-like growth factors cross the blood-brain barrier.

1994 • 364 citations

Mechanisms of delayed cell death following hypoxic-ischemic injury in the immature rat: evidence for apoptosis during selective neuronal loss

1995 • 356 citations

The link between nutritional status and clinical outcome: can nutritional intervention modify it?

1988 • 341 citations

Insulin-Like Growth Factor and Potassium Depolarization Maintain Neuronal Survival by Distinct Pathways: Possible Involvement of PI 3-Kinase in IGF-1 Signaling

1997 • 294 citations

Decreases in Cerebral Microvasculature with Age Are Associated with the Decline in Growth Hormone and Insulin-Like Growth Factor 1*

1997 • 286 citations

Differential Cardiac Effects of Growth Hormone and Insulin-like Growth Factor1 in the Rat

1996 • 275 citations

Localization and ontogeny of growth hormone receptor gene expression in the central nervous system

1993 • 220 citations

Treatment of Growth Hormone-Deficient Adults with Recombinant Human Growth Hormone Increases the Concentration of Growth Hormone in the Cerebrospinal Fluid and Affects Neurotransmitters

1995 • 204 citations

The Effects of IGF-1 Treatment after Hypoxic-Ischemic Brain Injury in Adult Rats

1993 • 202 citations

Co-ordinated and cellular specific induction of the components of the IGF/IGFBP axis in the rat brain following hypoxic–ischemic injury

1998 • 197 citations

Growth Hormone Dependence of Somatomedin-C/lnsulin-Like Growth Factor-I and Insulin-Like Growth Factor-ll Messenger Ribonucleic Acids*

1987 • 186 citations

The Effect of Prolonged Modification of Cerebral Temperature on Outcome after Hypoxic-Ischemic Brain Injury in the Infant Rat

1996 • 179 citations

Growth hormone receptor messenger ribonucleic acid distribution in the adult male rat brain and its colocalization in hypothalamic somatostatin neurons.

1992 • 145 citations

EARLY AND LATE MECHANISMS OF INCREASED VASCULAR PERMEABILITY FOLLOWING EXPERIMENTAL CEREBRAL INFARCTION

1979 • 144 citations

Localization of insulin-like growth factor-1 mRNA in murine central nervous system during postnatal development

1991 • 144 citations

Correlation between insulin-like growth factor (IGF)-binding protein 5 and IGF-I gene expression during brain development

1993 • 138 citations

Spatial and Temporal Changes in the Insulin-Like Growth Factor (IGF) Axis Indicate Autocrine/Paracrine Actions of IGF-I within Wounds of the Rat Brain*

1997 • 110 citations

Insulin-like growth factors cross the blood-brain barrier

1994 • 107 citations

Delayed Seizures Occurring with Hypoxic- Ischemic Encephalopathy in the Fetal Sheep

1990 • 106 citations

Traumatic brain injuries: structural changes

1991 • 102 citations

Autoradiographic Localization of Leptin Binding in the Choroid Plexus ofob/obanddb/dbMice

1996 • 102 citations

Growth hormone receptor messenger ribonucleic acid distribution in the adult male rat brain and its colocalization in hypothalamic somatostatin neurons

1992 • 101 citations

Plasma Insulin-like Growth Factor I and IGF Binding Protein 3 Levels in Patients With Acute Cerebral Ischemic Injury

1997 • 91 citations

Insulin and insulinlike growth factor 1 (IGF-1) receptors during central nervous system development: expression of two immunologically distinct IGF-1 receptor beta subunits.

1989 • 84 citations

Unexpected immunoreactivities of intermediate filament antibodies in human brain and brain tumors.

1991 • 81 citations

Insulin-like growth factor II is induced during wound repair following hypoxic-ischemic injury in the developing rat brain

1995 • 77 citations

Decreases in Cerebral Microvasculature with Age Are Associated with the Decline in Growth Hormone and Insulin-Like Growth Factor 1

1997 • 74 citations

Valid measurements of total IGF concentrations in biological fluids. Recommendations from the 3rd International Symposium on Insulin-like Growth Factors

1994 • 71 citations

Effects of Growth Hormone on Cerebral Development: Morphological Studies

1996 • 55 citations

Growth hormone, insulin-like growth factor I, and motoneuron size

1997 • 52 citations

Growth hormone deficiency and hyperthermia during exercise: a controlled study of sixteen GH-deficient patients.

1995 • 51 citations

Regulation of Insulin-Like Growth Factor I (IGF-I) Gene Expression in Brain of Transgenic Mice Expressing an IGF-I-Luciferase Fusion Gene*

1997 • 50 citations

Early Localization of¹²⁵I-Labeled Human Growth Hormone in Adrenals and Other Organs of Immature Hypophysectomized Rats

1971 • 48 citations

Two models for determining the mechanisms of damage and repair after hypoxic-ischaemic injury in the developing rat brain

1994 • 47 citations

Spatial and Temporal Changes in the Insulin-Like Growth Factor (IGF) Axis Indicate Autocrine/Paracrine Actions of IGF-I within Wounds of the Rat Brain

1997 • 47 citations

Fetal Bin Growth: Selective Action by Growth Hormone

1974 • 47 citations

Studies on the accessibility of prolactin and growth hormone to brain: effect of opiate agonists on hormone levels in serial, simultaneous plasma and cerebrospinal fluid samples in the rhesus monkey

1982 • 44 citations

Effects of Bovine Growth Hormone on the Retarded Cerebral Development Induced by Neonatal Hydrocortisone Intoxication

1982 • 41 citations

Prenatal action of growth hormone on brain and behaviour

1974 • 41 citations

Vascular permeability to growth hormone in the rat central nervous system after focal spinal cord injury. Influence of a new anti-oxidant H 290/51 and age

1995 • 40 citations

Aging effects on growth hormone receptor binding in the brain

1997 • 40 citations

Decreased Growth Hormone Receptor Expression in Long Bones from Toothless (Osteopetrotic) Rats and Restoration by Treatment with Colony-Stimulating Factor-1

1996 • 37 citations

Metabolic Basis for the Diabetogenic Action of Growth Hormone in the Obese (ob/ob) Mouse*

1987 • 35 citations

Growth hormone deficiency and hyperthermia during exercise: a controlled study of sixteen GH-deficient patients

1995 • 35 citations

Factors Contributing to the Poor Myelination in the Brain of the Snell Dwarf Mouse

1982 • 32 citations

Is the central nervous system a target for growth hormone and insulin‐like growth factors?

1995 • 27 citations

Developmental expression of the growth hormone receptor gene in the rat hypothalamus

1993 • 22 citations

Retarded cerebral growth of hormone-deficient mice

1991 • 20 citations

Regulation of Insulin-Like Growth Factor I (IGF-I) Gene Expression in Brain of Transgenic Mice Expressing an IGF-I-Luciferase Fusion Gene

1997 • 18 citations

Valid measurements of total IGF concentrations in biological fluids. Recommendations from the 3rd International Symposium on Insulin-like Growth Factors

1995 • 18 citations

Stimulatory Effect of Human, but not Bovine, Growth Hormone Expression on Numbers of Tuberoinfundibular Dopaminergic Neurons in Transgenic Mice*

1997 • 14 citations

Pretreatment with bovine growth hormone is as effective as treatment during metabolic stress to reduce catabolism in fasted lambs.

1996 • 11 citations

Specific abnormalities in a visual motor psychological test in short children with abnormal growth hormone secretion

1997 • 10 citations

Pretreatment with bovine growth hormone is as effective as treatment during metabolic stress to reduce catabolism in fasted lambs

1996 • 5 citations

Stimulatory Effect of Human, but not Bovine, Growth Hormone Expression on Numbers of Tuberoinfundibular Dopaminergic Neurons in Transgenic Mice

1997 • 5 citations

GROWTH PROMOTION BY GROWTH HORMONE AND INSULIN-LIKE GROWTH FACTOR-I IN THE RAT

1989 • 4 citations