Growth hormone, insulin-like growth factor I, and motoneuron size

Scaling, why is animal size so important?

1984 • 2,693 citations

Problems of Relative Growth.

1994 • 2,148 citations

The Problems of Relative Growth

1932 • 1,813 citations

Developmental Neurobiology

1978 • 1,211 citations

Insulin‐like growth factors I and II

1990 • 1,006 citations

Scaling: Why is Animal Size so Important?

1985 • 720 citations

The numbers of limb motor neurons in the human lumbosacral cord throughout life

1977 • 574 citations

Growth Enhancement of Transgenic Mice Expressing Human Insulin-Like Growth Factor I*

1988 • 481 citations

Insulin-like growth factor I increases brain growth and central nervous system myelination in tTransgenic mice

1993 • 468 citations

Regulation of rat growth hormone receptor gene expression

1989 • 446 citations

Recombinant human insulin-like growth factor I stimulates growth and has distinct effects on organ size in hypophysectomized rats.

1988 • 424 citations

Increase in Cell Number as a Factor in the Growth of the Organs and Tissues of the Young Male Rat

1962 • 349 citations

In vivo actions of insulin-like growth factor-I (IGF-I) on brain myelination: studies of IGF-I and IGF binding protein-1 (IGFBP-1) transgenic mice

1995 • 257 citations

Localization and ontogeny of growth hormone receptor gene expression in the central nervous system

1993 • 220 citations

Expression of Insulin-Like Growth Factor I Stimulates Normal Somatic Growth in Growth Hormone-Deficient Transgenic Mice

1990 • 195 citations

Growth Hormone Dependence of Somatomedin-C/lnsulin-Like Growth Factor-I and Insulin-Like Growth Factor-ll Messenger Ribonucleic Acids*

1987 • 186 citations

Expression of Insulin-Like Growth Factor I in Transgenic Mice with Elevated Levels of Growth Hormone Is Correlated with Growth*

1988 • 182 citations

Enhanced growth of small bowel in transgenic mice overexpressing bovine growth hormone

1993 • 163 citations

Growth Allometry of the Organs in Giant Transgenic Mice*

1987 • 136 citations

Lumbar Motoneurons of Man II: The Number and Diameter Distribution of Large- and Intermediate-Diameter Cytons in “Motoneuron Columns” of Spinal Cord of Man

1977 • 133 citations

Cellular analyses of hormone influence on motoneuronal development and function

1986 • 113 citations

Muscle changes in acromegaly.

1976 • 97 citations

Use of Gene Transfer to Increase Animal Growth

1985 • 96 citations

Beneficial effects of insulin-like growth factor-I on wobbler mouse motoneuron disease

1995 • 93 citations

Insulin-Like Growth Factors and Aging

1987 • 85 citations

Clinical Endocrine Physiology

1987 • 74 citations

Sexual dimorphism and androgen effects on spinal motoneurons innervating the rat flexor digitorum brevis

1991 • 73 citations

EFFECT OF EXCESSIVE SECRETION OF GROWTH HORMONE ON TISSUES OF THE RAT, WITH PARTICULAR REFERENCE TO THE HEART AND SKELETAL MUSCLE

1980 • 71 citations

Characterization of growth hormone binding sites in rat brain

1994 • 71 citations

The sizes of motoneurons supplying hindlimb muscles in the mouse

1981 • 62 citations

Effect of Hypophysectomy on Growth Hormone Receptor Gene Expression in Rat Tissues*

1990 • 59 citations

Target-dependent hormonal control of neuron size in the rat spinal nucleus of the bulbocavernosus

1991 • 57 citations

Expression of Insulin‐like Growth Factor‐I in Transgenic Mice^a

1993 • 55 citations

MYOPATHY IN ACROMEGALY

1970 • 54 citations

Molecular biology of the insulin-like growth factors

1990 • 51 citations

The determination of cell volume

1953 • 50 citations

Growth Hormone Receptors ‐ their Structure, Location and Role

1990 • 49 citations

Timing and duration of dihydrotestosterone treatment affect the development of motoneuron number and morphology in a sexually dimorphic rat spinal nucleus

1992 • 47 citations

Transcription and Motoneuron Size

1994 • 46 citations

Distribution of growth hormone and thyroid-stimulating hormone in cerebrospinal fluid and pathological compartments of the central nervous system

1977 • 45 citations

Postnatal development and cell death in the sciatic motor nucleus of the mouse

1983 • 43 citations

The development of lateral motor column cells in the lumbo-sacral cord in rana pipiens. II. Development under the influence of thyroxin

1956 • 40 citations

Quantitative studies on the postnatal growth of the spinal cord and the vertebral column of the albino mouse

1969 • 36 citations

Evidence for Target Regulations of the Development of Androgen Sensitivity in Rat Spinal Motoneurons

1995 • 36 citations

Axotomy transiently down-regulates androgen receptors in motoneurons of the spinal nucleus of the bulbocavernosus

1995 • 34 citations

Changes in the amounts of cytoskeletal proteins within the perikarya and axons of regenerating frog motoneurons.

1983 • 32 citations

Reduced protein synthesis in spinal anterior horn neurons in wobbler mouse mutant

1980 • 30 citations

Thyrotropin-releasing hormone (TRH) in murine motor neuron disease (the wobbler mouse)

1987 • 29 citations

PRESENCE OF GROWTH HORMONE-RELEASING FACTOR-LIKE IMMUNOREACTIVITY IN HUMAN CEREBROSPINAL FLUID

1985 • 29 citations

Changes in weight and volume of rat spinal cord motor neurons with increasing age

1968 • 26 citations

Regulation of Growth Hormone Receptor and Binding Protein Expression in Domestic Species

1994 • 25 citations

STATISTICAL ANALYSIS OF THE ORGAN WEIGHTS IN 1,000 AUTOPSY CASES OF JAPANESE AGED OVER 60 YEARS

1987 • 23 citations

Observations on the medulla spinalis of the elephant with some comparative studies of the intumescentia cervicalis and the neurones of the columna anterior

1902 • 21 citations

Measurement of neuropeptides in the brain and spinal cord of Wobbler mouse: a model for motoneuron disease

1990 • 20 citations

Nuclear and cell body size in spinal motor neurons.

1991 • 17 citations

Functional and structural changes of rat plantaris motoneurons following compensatory hypertrophy of the muscle

1991 • 15 citations

CHOLINE ACETYLTRANSFERASE ACTIVITY IN LARGE VENTRAL SPINAL NEURONS

1977 • 15 citations

Acetylcholinesterase Distribution in Axotomized Frog Motoneurons

1982 • 13 citations

Growth hormone releasing factor in human cerebrospinal fluid

1987 • 13 citations

HISTOMETRIC CHARACTERISTICS AND REGENERATIVE CAPACITY IN WOBBLER MOUSE MOTOR NEURON DISEASE

1990 • 12 citations

Relationship between the circulating levels of adenohypophyseal hormones in blood and in cerebrospinal fluid.

1984 • 11 citations

Motor units in cat muscles: anatomical considerations in relation to motor unit types.

1982 • 10 citations

Heat production of different cells.

1948 • 9 citations

The measurement of motor cell volumes in rats

1981 • 6 citations

Synchronous, intersegments I responses in motoneurons to lumbar ventral root injury

1994 • 5 citations

Isolation of motoneuron cell bodies from spinal cord stored at −70°C in ethylene glycol

1989 • 4 citations

Radiolabeling motoneuron proteins in the isolated frog spinal cord preparation

1994 • 3 citations