A Novel LacZ Reporter Mouse Reveals Complex Regulation of the Progesterone Receptor Promoter During Mammary Gland Development

Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial

2002 • 15,184 citations

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

1992 • 4,885 citations

MOLECULAR MECHANISMS OF ACTION OF STEROID/THYROID RECEPTOR SUPERFAMILY MEMBERS

1994 • 2,875 citations

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

1988 • 1,690 citations

Menopausal Estrogen and Estrogen-Progestin Replacement Therapy and Breast Cancer Risk

2000 • 1,075 citations

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/NeuroD-deficient mice

1997 • 1,011 citations

Effect of Hormone Replacement Therapy on Breast Cancer Risk: Estrogen Versus Estrogen Plus Progestin

2000 • 879 citations

Conditional control of gene expression in the mouse

2001 • 774 citations

Subgroup of Reproductive Functions of Progesterone Mediated by Progesterone Receptor-B Isoform

2000 • 693 citations

Dissociation between steroid receptor expression and cell proliferation in the human breast.

1997 • 623 citations

Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases

2000 • 527 citations

Estrogen receptors α and β in the rodent mammary gland

2000 • 357 citations

Pattern of distribution of cells positive for estrogen receptor α and progesterone receptor in relation to proliferating cells in the mammary gland

1999 • 356 citations

The A and B isoforms of the human progesterone receptor: two functionally different transcription factors encoded by a single gene.

1999 • 337 citations

Temporal, spatial, and cell type–specific control of Cre-mediated DNA recombination in transgenic mice

1999 • 229 citations

Inverted repeat structure of the Sry locus in mice.

1992 • 195 citations

Identification of multiple, widely spaced estrogen-responsive regions in the rat progesterone receptor gene.

1994 • 191 citations

Murine mammary gland carcinogenesis is critically dependent on progesterone receptor function.

1999 • 190 citations

Mutual and Intercompartmental Regulation of Estrogen Receptor and Progesterone Receptor Expression in the Mouse Uterus1

1998 • 183 citations

Regulation of mammary gland development by tissue interaction.

1999 • 183 citations

Engineering of a Mouse for the in Vivo Profiling of Estrogen Receptor Activity

2001 • 176 citations

Endocrine Defects in Mice Carrying a Null Mutation for the Progesterone Receptor Gene*

1997 • 169 citations

Effects of Castration and Chronic Steroid Treatments on Hypothalamic Gonadotropin-Releasing Hormone Content and Pituitary Gonadotropins in Male Wild-Type and Estrogen Receptor-α Knockout Mice

1998 • 168 citations

Postnatal mammary gland morphogenesis

2001 • 165 citations

Absence of Gonadotropin Surges and Gonadotropin-Releasing Hormone Self-Priming in Ovariectomized (OVX), Estrogen (E2)-Treated, Progesterone Receptor Knockout (PRKO) Mice*

1999 • 161 citations

C/EBPβ (CCAAT/Enhancer Binding Protein) Controls Cell Fate Determination during Mammary Gland Development

2000 • 156 citations

Ovulation: a multi-gene, multi-step process

2000 • 153 citations

Response: Re: Effect of Hormone Replacement Therapy on Breast Cancer Risk: Estrogen Versus Estrogen Plus Progestin

2000 • 141 citations

Progesterone induces side-branching of the ductal epithelium in the mammary glands of peripubertal mice

2000 • 135 citations

Tissue Compartment-Specific Estrogen Receptor-α Participation in the Mouse Uterine Epithelial Secretory Response**Presented in part at the 30th Annual Meeting of the Society for the Study of Reproduction, Portland, Oregon, August 1997. This work was supported by NIH Grants AG-15500 (to P.S.C.), ES-08272 (to D.B.L.), and CA-05388 and AG-13784 (to G.R.C.).

1999 • 110 citations

Parathyroid hormone-related protein signaling is necessary for sexual dimorphism during embryonic mammary development

1999 • 106 citations

Molecular cloning, sequence analyses, and expression of complementary DNA encoding murine progesterone receptor

1991 • 101 citations

Progesterone, in Addition to Estrogen, Induces Cyclin D1 Expression in the Murine Mammary Epithelial Cell, in Vivo*

1997 • 100 citations

The mammary gland: a model for development.

1999 • 89 citations

Progesterone Receptor A and B Messenger Ribonucleic Acid Levels in the Anterior Pituitary of Rats Are Regulated by Estrogen1

2000 • 78 citations

Progesterone receptors in the mouse mammary duct: distribution and developmental regulation.

1996 • 76 citations

Development of an ER Action Indicator Mouse for the Study of Estrogens, Selective ER Modulators (SERMs), and Xenobiotics

2001 • 73 citations

Regulation and Localization of Estrogen and Progestin Receptors in the Pituitary of Steroid-Treated Monkeys*

1990 • 57 citations

Murine Progesterone Receptor Expression in Proliferating Mammary Epithelial Cells During Normal Pubertal Development and Adult Estrous Cycle: Association with ERα and ERβ Status

1999 • 54 citations

A reappraisal of progesterone action in the mammary gland.

2000 • 43 citations

Nucleic Acid Sequence and DNase Hypersensitive Sites of the 5′ Region of the Mouse Progesterone Receptor Gene

1994 • 26 citations

PR Localization and Anterior Pituitary Cell Populationsin Vitroin Ovariectomized Wild-Type and PR-Knockout Mice

2001 • 25 citations

Immunohistochemical Evidence for the Presence of Progesterone Receptor in Rat Submandibular Glands.

1991 • 18 citations

Progesterone: Lessons from the Progesterone Receptor Knockout

2000 • 13 citations

MAMMARY GLAND GROWTH IN MALE MICE OF THE CHI STRAIN AFTER HYPOPHYSECTOMY AND CASTRATION

1958 • 11 citations

Mammary gland growth and serum levels of prolactin and growth hormone in four strains of male mice in comparison with females

1987 • 4 citations

The Progesterone Receptor Knockout Mouse Model: New Insights into Progesterone Action In Vivo

2003 • 1 citations