Atypical features of familial hemophagocytic lymphohistiocytosis

Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B

1995 • 720 citations

Familial hemophagocytic lymphohistiocytosis

1983 • 567 citations

Hypercytokinemia in familial hemophagocytic lymphohistiocytosis

1991 • 498 citations

Hemophagocytic lymphohistiocytosis. Report of 122 children from the International Registry. FHL Study Group of the Histiocyte Society.

1996 • 476 citations

FAMILIAL HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS

1998 • 281 citations

Spectrum of Perforin Gene Mutations in Familial Hemophagocytic Lymphohistiocytosis

2001 • 253 citations

Perforin expression in cytotoxic lymphocytes from patients with hemophagocytic lymphohistiocytosis and their family members

2002 • 244 citations

Hypercytokinemia in Hemophagocytic Syndrome

1993 • 242 citations

Perforin and Granzymes: Crucial Effector Molecules in Cytolytic T Lymphocyte and Natural Killer Cell-Mediated Cytotoxicity

1995 • 153 citations

Linkage of Familial Hemophagocytic Lymphohistiocytosis to 10q21-22 and Evidence for Heterogeneity

1999 • 146 citations

Defective Natural Killer Cell Function in Patients with Hemophagocytic Lymphohistiocytosis and in First Degree Relatives

1998 • 137 citations

Perforin and Lymphocyte‐mediated Cytolysis

1995 • 78 citations

Low natural killer activity and central nervous system disease as a high‐risk prognostic indicator in young patients with hemophagocytic lymphohistiocytosis

2002 • 51 citations

Hyper‐interleukin (IL)‐6‐naemia in haemophagocytic lymphohistiocytosis

1996 • 38 citations

Proteases and Cell-Mediated Cytotoxicity

1998 • 27 citations