Melanosomal pH Controls Rate of Melanogenesis, Eumelanin/Phaeomelanin Ratio and Melanosome Maturation in Melanocytes and Melanoma Cells

Defective acidification of intracellular organelles in cystic fibrosis

1991 • 490 citations

The Pigmentary System: Physiology and Pathophysiology

1999 • 426 citations

A gene for the mouse pink-eyed dilution locus and for human type II oculocutaneous albinism

1993 • 411 citations

Microanalysis of eumelanin and pheomelanin in hair and melanomas by chemical degradation and liquid chromatography

1985 • 389 citations

The pigmentary system : physiology and pathophysiology

1998 • 339 citations

Pheomelanin as well as Eumelanin Is Present in Human Epidermis

1991 • 303 citations

Melanosomes Are Specialized Members of the Lysosomal Lineage of Organelles

1995 • 270 citations

Defective Acidification in Human Breast Tumor Cells and Implications for Chemotherapy

1998 • 265 citations

Role of Tyrosinase as the Determinant of Pigmentation in Cultured Human Melanocytes

1993 • 256 citations

Mammalian tyrosinase. A comparison of tyrosine hydroxylation and melanin formation

1976 • 208 citations

Organization and sequence of the human P gene and identification of a new family of transport proteins

1995 • 197 citations

Regulation of the Catalytic Activity of Preexisting Tyrosinase in Black and Caucasian Human Melanocyte Cell Cultures

2001 • 151 citations

Effect of Arbutin on Melanogenic Proteins in Human Melanocytes

1998 • 145 citations

Mammalian tyrosinase: biosynthesis, processing, and modulation by melanocyte-stimulating hormone.

1988 • 135 citations

Complementation of Hypopigmentation in p-Mutant (Pink-Eyed Dilution) Mouse Melanocytes by Normal Human P cDNA, and Defective Complementation by OCA2 Mutant Sequences

1997 • 123 citations

The Melanosome: The Perfect Model for Cellular Responses to the Environment

2000 • 117 citations

Pigment-Cell Biology

1968 • 114 citations

Nle4DPhe7α-Melanocyte-Stimulating Hormone Increases the Eumelanin:Phaeomelanin Ratio in Cultured Human Melanocytes

1995 • 113 citations

Phaeomelanin versus eumelanin as a chemical indicator of ultraviolet sensitivity in fair-skinned subjects at high risk for melanoma: a pilot study

1998 • 110 citations

Does α‐MSH Have a Role in Regulating Skin Pigmentation in Humans?

1998 • 108 citations

pH of Melanosomes of B 16 Murine Melanoma Is Acidic: Its Physiological Importance in the Regulation of Melanin Biosynthesis

1993 • 104 citations

Lysosomal Hydrolases Are Present in Melanosomes and Are Elevated in Melanizing Cells

1995 • 100 citations

α‐MSH and the Regulation of Melanocyte Function

1999 • 98 citations

Ultrastructural Observations on the Hair Bulb Melanocytes and Melanosomes in Acute Alopecia Areata

1990 • 96 citations

Eumelanin and Phaeomelanin Contents of Human Epidermis and Cultured Melanocytes

1995 • 96 citations

The tyrosinase gene family--interactions of melanogenic proteins to regulate melanogenesis.

1994 • 88 citations

STUDIES ON RADIATION‐INDUCED TANNING OF SKIN*

1963 • 70 citations

The Pinkeyed‐Dilution Protein and the Eumelanin/Pheomelanin Switch: In Support of a Unifying Hypothesis

1995 • 64 citations

Variations in melanin formation by cultured melanocytes from different skin types

1998 • 48 citations

Activation of melanogenesis by vacuolar type H⁺‐ATPase inhibitors in amelanotic, tyrosinase positive human and mouse melanoma cells

2000 • 47 citations

Regulation of Tyrosinase Synthesis and its Processing in the Hair Follicular Melanocytes of the Mouse During Eumelanogenesis and Phaeomelanogenesis

1989 • 45 citations

Optimized assay for mammalian tyrosinase (polyhydroxyl phenyloxidase)

1984 • 42 citations

pH-dependent interconversion of two forms of tyrosinase in human skin

1988 • 41 citations

pH‐dependent interconvertible allosteric forms of murine melanoma tyrosinase

1987 • 41 citations

Stimulation by Ionophores of Tyrosinase Activity of Mouse Melanoma Cells in Culture

1985 • 39 citations

Stimulation of tyrosinase activity of cultured melanoma cells by lysosomotropic agents

1983 • 37 citations

Expression of transporter associated with antigen processing 1 and 2 (TAP1/2) in malignant melanoma cell lines

1997 • 33 citations

Effects of genic substitution at the agouti, brown, albino, dilute, and pink-eyed dilution loci on the proliferation and differentiation of mouse epidermal melanocytes in serum-free culture

1998 • 29 citations

Hormonal Regulation of Melanogenesis in Mouse Melanoma and in Human Melanocytes

1993 • 26 citations

Comparison of tyrosinase levels in amelanotic and melanotic melanoma cell cultures by a competitive enzyme‐linked immunoadsorbent assay and by immunotitration analysis

1988 • 24 citations

Evidence for a Calcium/Calmodulin Involvement in Density‐Dependent Melanogenesis in Murine B16 Melanoma Cells

1991 • 23 citations

Tyrosinase Expression and Melanogenesis in Melanotic and Amelanotic B16 Mouse Melanoma Cells

1991 • 22 citations

Differentiation apparently repressed by the nucleus

1987 • 18 citations

Characterization of Mg2+-ATPase activity in isolated B16 murine melanoma melanosomes.

1998 • 17 citations

Electron Microscopic Evidence for Stimulation of Melanosomal Maturation by Lysosomotropic Agents and Monensin in Cultured B16 Mouse Melanoma Cells

1987 • 8 citations

Regulation of Tyrosinase in Hair Follicular Melanocytes of the Mouse during the Synthesis of Eumelanin and Phaeomelanin

1991 • 5 citations