Single-step selection of mouse FM3A cell mutants defective in thymidylate synthetase

Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed Recombinants

1964 • 2,108 citations

On the nature of hereditable variation in cultured somatic cells

1976 • 497 citations

Genetics of somatic mammalian cells, VII. Induction and isolation of nutritional mutants in Chinese hamster cells.

1968 • 460 citations

Fluorinated Pyrimidines and Their Nucleosides

1975 • 333 citations

Polyethylene glycol-induced mammalian cell hybridization: Effect of polyethylene glycol molecular weight and concentration

1976 • 300 citations

Improved Method for the Isolation of Thymine-Requiring Mutants of Escherichia coli

1965 • 286 citations

Antineoplastic and Immunosuppressive Agents

1975 • 236 citations

Chapter 7: Isolation of Mutants of Cultured Mammalian Cells

1973 • 232 citations

Genetics of somatic mammalian cells. V. Treatment with 5-bromodeoxyuridine and visible light for isolation of nutritionally deficient mutants.

1967 • 222 citations

An Isotopic Assay for Thymidylate Synthetase^*

1966 • 212 citations

Chromosome stability in CHO cells

1977 • 155 citations

Establishment of Cell Lines <i>in vitro</i> from a Mammary Ascites Tumor of Mouse and Biological Properties of the Established Lines in a Serum Containing Medium

1966 • 124 citations

Isolation of Temperature-Sensitive Mutants of L-Cells

1970 • 108 citations

Evidence for functional hemizygosity at the Emtr locus in CHO cells through segregation analysis

1978 • 74 citations

Thymidylate synthetase purified to homogeneity from human leukemic cells.

1979 • 59 citations

Two thymidylate synthetases in Bacillus subtilis.

1978 • 56 citations

Mutagenesis to aminopterin resistance in cultured hamster cells

1971 • 38 citations

Increase in dATP pool in aphidicolin-resistant mutants of mouse FM3A cells

1979 • 38 citations

Selection of Chinese hamster cells auxotrophic for thymidine by 1-#x03B2;-D-arabinofuranosyl cytosine

1979 • 37 citations

Electrophoretic shift mutants in Chinese hamster ovary cells: evidence for genetic diploidy.

1978 • 37 citations

Evidence for variation in the number of functional gene copies at the Ama^R locus in chinese hamster cell lines

1978 • 28 citations

Interaction of regulator proteins with recognition sequences of DNA

1974 • 18 citations

PURINE AND PYRIMIDINE METABOLISM OF CELLS IN CULTURE

1972 • 15 citations

ISOLATION AND CHARACTERIZATION OF NUTRITIONALLY DEFICIENT CELLS FROM CULTURED CHINESE HAMSTER HAI CELLS BY A REPLICA PLATING METHOD

1975 • 4 citations