Teniposide, a topoisomerase II inhibitor, prevents chromosome condensation and separation but not decondensation in fertilized surf clam (Spisula solidissima) oocytes

DNA TOPOISOMERASES

1985 • 1,524 citations

DNA Topoisomerases

1981 • 977 citations

Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.

1984 • 896 citations

Topoisomerase II is a structural component of mitotic chromosome scaffolds.

1985 • 751 citations

DNA topoisomerase II is required at the time of mitosis in yeast

1985 • 747 citations

DNA Gyrase and the Supercoiling of DNA

1980 • 713 citations

DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe

1987 • 691 citations

DNA topoisomerase II mutant of Saccharomyces cerevisiae: topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication.

1984 • 685 citations

Nuclear reconstitution in vitro: Stages of assembly around protein-free DNA

1987 • 550 citations

Metaphase chromosome structure

1986 • 538 citations

The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes

1986 • 534 citations

Localization of topoisomerase II in mitotic chromosomes.

1985 • 501 citations

Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.

1984 • 491 citations

In situ localization of DNA topoisomerase II, a major polypeptide component of the Drosophila nuclear matrix fraction.

1985 • 472 citations

Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organization.

1984 • 444 citations

Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle.

1988 • 415 citations

A homogeneous type II DNA topoisomerase from HeLa cell nuclei.

1981 • 361 citations

Disassembly of the nucleus in mitotic extracts: Membrane vesicularization, lamin disassembly, and chromosome condensation are independent processes

1987 • 349 citations

DNA Topoisomerase II Must Act at Mitosis To Prevent Nondisjunction and Chromosome Breakage

1989 • 302 citations

ATP-dependent DNA topoisomerase from D. melanogaster reversibly catenates duplex DNA rings

1980 • 292 citations

Mitotic spindle pulls but fails to separate chromosomes in type II DNA topoisomerase mutants: uncoordinated mitosis

1986 • 292 citations

The role of cyclin B in meiosis I.

1989 • 241 citations

Protein kinase C phosphorylates topoisomerase II: topoisomerase activation and its possible role in phorbol ester-induced differentiation of HL-60 cells.

1986 • 231 citations

DNA Topoisomerases-Enzymes that Catalyse the Breaking and Rejoining of DNA

1983 • 216 citations

Purification and characterization of a type II DNA topoisomerase from bovine calf thymus.

1985 • 215 citations

Phosphorylation of DNA topoisomerase II by casein kinase II: modulation of eukaryotic topoisomerase II activity in vitro.

1985 • 214 citations

FERTILIZATION AND ARTIFICIAL ACTIVATION IN THE EGG OF THE SURF-CLAM, SPISULA SOLIDISSIMA

1953 • 196 citations

Comparison of cytotoxicity and DNA breakage activity of congeners of podophyllotoxin including VP16-213 and VM26: a quantitative structure-activity relationship

1984 • 188 citations

Segregation of recombined chromosomes in meiosis I requires DNA topoisomerase II

1990 • 172 citations

DNA topoisomerase II must act at mitosis to prevent nondisjunction and chromosome breakage.

1989 • 167 citations

Yeast DNA topoisomerase II. An ATP-dependent type II topoisomerase that catalyzes the catenation, decatenation, unknotting, and relaxation of double-stranded DNA rings.

1982 • 164 citations

Decatenation of kinetoplast DNA by topoisomerases.

1980 • 159 citations

In vitro catenation and decatenation of DNA and a novel eucaryotic ATP-dependent topoisomerase

1980 • 134 citations

Phosphorylation of DNA topoisomerase II in vivo and in total homogenates of Drosophila Kc cells. The role of casein kinase II.

1988 • 126 citations

Anti-topoisomerase II recognizes meiotic chromosome cores

1989 • 118 citations

In vivo phosphorylation of the 170-kDa form of eukaryotic DNA topoisomerase II

1989 • 112 citations

The Molecular Biology of Fertilization

1989 • 103 citations

Self-assembling architecture

1988 • 92 citations

Effects of motility inhibitors during sea urchin fertilization

1981 • 91 citations

DNA topoisomerase II activity in nonreplicating, transcriptionally inactive, chicken late spermatids.

1989 • 82 citations

An ultrastructural analysis of fertilization in the surf clam, Spisula solidissima. I. Polar body formation and development of the female pronucleus

1970 • 81 citations

Effect of an epipodophyllotoxin derivative (VP 16-213) on macromolecular synthesis and mitosis in mastocytoma cells in vitro.

1974 • 77 citations

Purification and characterization of type II DNA topoisomerase from mouse FM3A cells: phosphorylation of topoisomerase II and modification of its activity

1990 • 70 citations

The effects of cytochalasin B on the events of fertilization in the surf clam,Spisula solidissima. I. Polar body formation

1972 • 70 citations

An ultrastructural analysis of fertilization in the surf clam, Spisula solidissima. II. Development of the male pronucleus and the association of the maternally and paternally derived chromosomes

1970 • 52 citations

Examination of living and fixed gametes and early embryos stained with supravital fluorochromes (Hoechst 33342 and 3,3′‐dihexyloxacarbocyanine iodide)

1986 • 39 citations

Quantitation of type II topoisomerase in oocytes and eggs of Xenopus laevis

1989 • 36 citations

Problems of Oocyte Maturation and the Control of Chromosome Cycles*

1985 • 29 citations

Sperm nuclear transformations consist of enlargement and condensation coordinate with stages of meiotic maturation in fertilized Spisula solidissima oocytes

1988 • 22 citations

Sperm nuclear dispersion coordinate with meiotic maturation in fertilized Spisula solidissima eggs

1983 • 18 citations

Cyclins and Regulation of the Cell Cycle in Early Embryos

1989 • 16 citations