Alzheimer's lesions labelled by anti‐ubiquitin antibodies: comparison with other staining techniques. A study of 15 cases with graded intellectual status in ageing and Alzheimer's disease

STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT

1986 • 45,881 citations

Akufo and Ibarapa

1965 • 16,925 citations

The Lewy body variant of Alzheimer's disease

1990 • 1,057 citations

Ubiquitin Is a Component of Paired Helical Filaments in Alzheimer's Disease

1987 • 834 citations

Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains.

1987 • 606 citations

Senile dementia of Lewy body type

1990 • 573 citations

Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodies in muscle, and mallory bodies in alcoholic liver disease

1988 • 541 citations

A4 amyloid protein deposition and the diagnosis of Alzheimer's disease

1988 • 367 citations

Alz-50, Ubiquitin and Tau Immunoreactivity of Neurofibrillary Tangles, Pick Bodies and Lewy Bodies

1988 • 238 citations

A4 Protein in Alzheimer's Disease: Primary and Secondary Cellular Events in Extracellular Amyloid Deposition

1989 • 236 citations

A filamentous inclusion body within anterior horn neurones in motor neurone disease defined by immunocytochemical localisation of ubiquitin

1988 • 226 citations

Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases.

1988 • 201 citations

Abnormal phosphorylation of tau precedes ubiquitination in neurofibrillary pathology of Alzheimer disease

1991 • 177 citations

Large amounts of neocortical βA4 deposits without neuritic plaques nor tangles in a psychometrically assessed, non-demented person

1990 • 174 citations

Ubiquitin immunoreactive structures in normal human brains. Distribution and developmental aspects.

1990 • 170 citations

Subtypes and differential laminar distributions of ?A4 deposits in Alzheimer's disease: relationship with the intellectual status of 26 cases

1991 • 165 citations

Laminar distribution of neocortical senile plaques in senile dementia of the alzheimer type

1986 • 154 citations

Tau, paired helical filaments and amyloid in the neocortex: a morphometric study of 15 cases with graded intellectual status in aging and senile dementia of Alzheimer type

1989 • 136 citations

Ubiquitin immunoelectron microscopy of dystrophic neurites in cerebellar senile plaques of Alzheimer's disease

1990 • 100 citations

Rating of the lesions in senile dementia of the Alzheimer type: concordance between laboratories A European multicenter study under the auspices of EURAGE

1990 • 98 citations

Ubiquitin-protein conjugates in Alzheimer's lesions

1987 • 97 citations

Ubiquitin has intrinsic proteolytic activity: implications for cellular regulation.

1987 • 92 citations

Quantitative assessment of the density of neurofibrillary tangles and senile plaques in senile dementia of the Alzheimer type. Comparison of immunocytochemistry with a specific antibody and Bodian's protargol method

1987 • 90 citations

Cortical atrophy in senile dementia of the Alzheimer type is mainly due to a decrease in cortical length

1985 • 88 citations

Ubiquitin is a component of the microtubule network.

1988 • 88 citations

Selective presence of ubiquitin in intracellular inclusions.

1989 • 88 citations

COMPARISON OF SEVEN STAINING METHODS FOR SENILE PLAQUES AND NEUROFIBRILLARY TANGLES IN A PROSPECTIVE SERIES OF 15 ELDERLY PATIENTS

1989 • 81 citations

Ubiquitin is a component of neurofibrillary tangles in a variety of neurodegenerative diseases

1988 • 77 citations

Immunochemical Properties of Ubiquitin Conjugates in the Paired Helical Filaments of Alzheimer Disease

1989 • 68 citations

Does amyloid precede paired helical filaments in the senile plaque? A study of 15 cases with graded intellectual status in aging and Alzheimer disease

1988 • 62 citations

Alzheimer's Disease and Related Disorders

1990 • 61 citations

Ubiquitin and microtubule-associated protein tau immunoreactivity each define distinct structures with differing distributions and solubility properties in Alzheimer brain.

1988 • 58 citations

Age‐related ubiquitin deposits in dystrophic neurites: an immunoelectron microscopic study

1992 • 54 citations

Immunochemical Probes of Ubiquitin Pool Dynamics

1988 • 38 citations

Ubiquitin-immunoreactive Dystrophic Neurites in Downʼs Syndrome Brains

1991 • 28 citations

FIBRE DISORGANIZATION IN THE NEOCORTEX OF PATIENTS WITH SENILE DEMENTIA OF THE ALZHEIMER TYPE

1989 • 22 citations