The evolving role of microRNAs in animal gene expression

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

1993 • 12,238 citations

Prediction of Mammalian MicroRNA Targets

2003 • 5,070 citations

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

2005 • 4,706 citations

Combinatorial microRNA target predictions

2005 • 4,543 citations

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

1993 • 4,021 citations

Silencing of microRNAs in vivo with ‘antagomirs’

2005 • 3,846 citations

Principles of MicroRNA–Target Recognition

2005 • 2,335 citations

Control of leaf morphogenesis by microRNAs

2003 • 1,756 citations

A brain-specific microRNA regulates dendritic spine development

2006 • 1,746 citations

Specificity of microRNA target selection in translational repression

2004 • 1,631 citations

The Widespread Impact of Mammalian MicroRNAs on mRNA Repression and Evolution

2005 • 1,482 citations

Inhibition of Translational Initiation by Let-7 MicroRNA in Human Cells

2005 • 1,408 citations

Specific Effects of MicroRNAs on the Plant Transcriptome

2005 • 1,404 citations

Regulation by let-7 and lin-4 miRNAs Results in Target mRNA Degradation

2005 • 1,311 citations

Ribo-gnome: The Big World of Small RNAs

2005 • 1,276 citations

Animal MicroRNAs Confer Robustness to Gene Expression and Have a Significant Impact on 3′UTR Evolution

2005 • 1,079 citations

Prediction and validation of microRNAs and their targets

2005 • 376 citations

Pervasive regulation of Drosophila Notch target genes by GY-box-, Brd-box-, and K-box-class microRNAs

2005 • 290 citations

Micro-RNA Regulation of the Mammalian lin-28 Gene during Neuronal Differentiation of Embryonal Carcinoma Cells

2005 • 263 citations

Negative regulatory sequences in the lin-14 3'-untranslated region are necessary to generate a temporal switch during Caenorhabditis elegans development.

1991 • 207 citations