Elevation of beta-adrenergic receptor density in human lymphocytes after propranolol administration.

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

New Tables for Multiple Comparisons with a Control

1964 • 3,084 citations

A Multiple Comparison Procedure for Comparing Several Treatments with a Control

1955 • 1,399 citations

Control of Heart Rate by the Autonomic Nervous System

1966 • 801 citations

Development of β-adrenergic receptor subsensitivity by antidepressants

1977 • 727 citations

Relation of Heart Rate and Systolic Blood Pressure to the Onset of Pain in Angina Pectoris

1967 • 563 citations

Binding characteristics of a radiolabeled agonist and antagonist at central nervous system alpha noradrenergic receptors.

1977 • 544 citations

Presynaptic modulation of beta adrenergic receptors in rat cerebral cortex after treatment with antidepressants.

1978 • 440 citations

Simultaneous determination of beta-1 and beta-2-adrenergic receptors in tissues containing both receptor subtypes.

1979 • 418 citations

Propranolol-Withdrawal Rebound Phenomenon

1975 • 400 citations

Identification of beta-adrenergic receptors in human lymphocytes by (-) (3H) alprenolol binding.

1976 • 398 citations

THE PHARMACOLOGICAL DIFFERENTIATION OF ADRENERGIC RECEPTORS*

1967 • 376 citations

Elevated beta-adrenergic receptor number after chronic propranolol treatment

1977 • 262 citations

Decreased Beta-Adrenergic Receptors on Polymorphonuclear Leukocytes after Adrenergic Therapy

1978 • 261 citations

Clinical pharmacology of propranolol.

1975 • 250 citations

Relative Roles of the Sympathetic and Parasympathetic Nervous Systems in the Reflex Control of Heart Rate

1965 • 249 citations

Binding of (125I)iodohydroxybenzylpindolol to putative beta-adrenergic receptors of rat glioma cells and other cell clones.

1976 • 238 citations

Subsensitivity of adenylate cyclase and decreased beta-adrenergic receptor binding after chronic exposure to (minus)-isoproterenol in vitro.

1975 • 235 citations

Coronary Artery Syndromes After Sudden Propranolol Withdrawal

1974 • 231 citations

Effects of exercise on myocardial force-velocity relations in intact unanesthetized man: relative roles of changes in heart rate, sympathetic activity, and ventricular dimensions.

1965 • 231 citations

Agonist-specific refractoriness induced by isoproterenol. Studies with mutant cells.

1976 • 219 citations

Mechanism of propranolol withdrawal phenomena.

1979 • 207 citations

Hypersensitivity to Adrenergic Stimulation after Propranolol Withdrawal in Normal Subjects

1977 • 186 citations

The Percentage of Monocytes among “Mononuclear” Cell Fractions Obtained from Normal Human Blood

1974 • 172 citations

Isoproterenol-induced desensitization of adenylate cyclase in human astrocytoma cells. Relation of loss of hormonal responsiveness and decrement in beta-adrenergic receptors.

1979 • 142 citations

Role of beta-adrenergic receptors in catecholamine-induced desensitization of adenylate cyclase in human astrocytoma cells.

1978 • 130 citations

WITHDRAWAL OF PROPRANOLOL AND MYOCARDIAL INFARCTION

1973 • 113 citations

Propranolol in Patients with Angina Pectoris

1967 • 111 citations

Disposition of propranolol VI. Independent variation in steady‐state circulating drug concentrations and half‐life as a result of plasma drug binding in man

1973 • 110 citations

Supersensitivity in rat cerebral cortex: pre- and postsynaptic effects of 6-hydroxydopamine at noradrenergic synapses.

1977 • 108 citations

Time Required for Complete Recovery from Chronic Propranolol Therapy

1973 • 107 citations

In Vitro Study of beta-Adrenergic Receptors

1977 • 99 citations

Abrupt propranolol withdrawal in angina pectoris: Effects on platelet aggregation and exercise tolerance

1978 • 92 citations

Binding of iodinated beta adrenergic antagonists to proteins derived from rat heart.

1976 • 85 citations

High-pressure liquid chromatographic method for the simultaneous quantitative analysis of propranolol and 4-hydroxypropranolol in plasma

1978 • 78 citations

Circulatory changes during the pain of angina pectoris

1966 • 78 citations

beta-Adrenergic receptors in rat brain.

1976 • 66 citations

WITHDRAWAL OF PROPRANOLOL AND MYOCARDIAL INFARCTION

1973 • 65 citations

Acute coronary syndromes following abrupt cessation of oral propranolol therapy.

1976 • 63 citations

Propranolol withdrawal and thyroid hormones in patients with essential hypertension

1978 • 62 citations

Discontinuation of Propranolol Therapy

1976 • 57 citations

Abrupt withdrawal of beta-blocking agents in patients with arterial hypertension. Effect on blood pressure, heart rate and plasma catecholamines and prolactin

1979 • 54 citations

Effects of Beta‐Adrenergic Blockade on Diurnal Variability of Blood Pressure and Plasma Noradrenaline Levels

1977 • 47 citations

Changes in blood pressure, heart rate, and plasma noradrenaline concentration after sudden withdrawal of propranolol.

1979 • 44 citations

Myocardial infarction after propranolol withdrawal

1974 • 42 citations

beta-Adrenergic receptors in rat brain.

1976 • 21 citations

RELATIVE ROLES OF THE SYMPATHETIC AND PARASYMPATHETIC NERVOUS SYSTEMS IN THE REFLEX CONTROL OF HEART RATE

1966 • 11 citations

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