Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Database resources of the National Center for Biotechnology Information: update

2003 • 10,877 citations

The Human Genome Browser at UCSC

2002 • 9,920 citations

Human MicroRNA Targets

2004 • 3,702 citations

Ultraconserved Elements in the Human Genome

2004 • 1,691 citations

ESEfinder: a web resource to identify exonic splicing enhancers

2003 • 1,543 citations

A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance

1998 • 1,090 citations

Predictive Identification of Exonic Splicing Enhancers in Human Genes

2002 • 1,035 citations

Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans

2002 • 1,026 citations

Variability and memory of protein levels in human cells

2006 • 588 citations

A distal enhancer and an ultraconserved exon are derived from a novel retroposon

2006 • 489 citations

Autoregulation of Polypyrimidine Tract Binding Protein by Alternative Splicing Leading to Nonsense-Mediated Decay

2004 • 395 citations

Database resources of the National Center for Biotechnology Information

2005 • 358 citations

Primary structure of the human splicing factor asf reveals similarities with drosophila regulators

1991 • 357 citations

The evolving roles of alternative splicing

2004 • 303 citations

Identification and analysis of alternative splicing events conserved in human and mouse

2005 • 299 citations

SC35 autoregulates its expression by promoting splicing events that destabilize its mRNAs

2001 • 299 citations

The splicing factor SRp20 modifies splicing of its own mRNA and ASF/SF2 antagonizes this regulation

1997 • 264 citations

A GFP-based reporter system to monitor nonsense-mediated mRNA decay

2005 • 217 citations

Quantitative microarray profiling provides evidence against widespread coupling of alternative splicing with nonsense-mediated mRNA decay to control gene expression

2006 • 216 citations

An unappreciated role for RNA surveillance

2004 • 186 citations

In Vivo Regulation of Alternative Pre-mRNA Splicing by the Clk1 Protein Kinase

1997 • 169 citations

Multiple roles of arginine/serine-rich splicing factors in RNA processing

2005 • 158 citations

Annotation of cis-regulatory elements by identification, subclassification, and functional assessment of multispecies conserved sequences

2005 • 147 citations

Evolutionary conservation and regulation of particular alternative splicing events in plant SR proteins

2006 • 109 citations

smg mutants affect the expression of alternatively spliced SR protein mRNAs in Caenorhabditis elegans

1997 • 92 citations

Survey of Conserved Alternative Splicing Events of mRNAs Encoding SR Proteins in Land Plants

2006 • 76 citations

Alternative Splicing of Intron 3 of the Serine/Arginine-rich Protein 9G8 Gene

2001 • 63 citations

Cloning of Caenorhabditis U2AF⁶⁵: an Alternatively Spliced RNA Containing a Novel Exon

1997 • 45 citations

Negative feedback regulation among SR splicing factors encoded by Rbp1 and Rbp1-like in Drosophila

2005 • 40 citations

Protein kinase clk/STY is differentially regulated during erythroleukemia cell differentiation: a bias toward the skipped splice variant characterizes postcommitment stages

2005 • 19 citations