Nitric Oxide in the Penis: Physiology and Pathology

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

Campbell's urology

1986 • 3,494 citations

Nitric oxide synthases in mammals

1994 • 2,762 citations

Nitric oxide, a novel neuronal messenger

1992 • 1,864 citations

Targeted disruption of the neuronal nitric oxide synthase gene

1993 • 1,300 citations

Nitric Oxide: A Physiologic Mediator of Penile Erection

1992 • 1,187 citations

Nitric Oxide as a Mediator of Relaxation of the Corpus Cavernosum in Response to Nonadrenergic, Noncholinergic Neurotransmission

1992 • 1,028 citations

Nitric Oxide: A Physiologic Messenger

1994 • 915 citations

Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle

1990 • 854 citations

The Nitric Oxide Synthase Family of Proteins

1994 • 465 citations

A nitric oxide-like factor mediates nonadrenergic-noncholinergic neurogenic relaxation of penile corpus cavernosum smooth muscle.

1991 • 442 citations

Oxygen tension regulates the nitric oxide pathway. Physiological role in penile erection.

1993 • 294 citations

Dihydrotestosterone is the active androgen in the maintenance of nitric oxide-mediated penile erection in the rat.

1995 • 275 citations

Immunohistochemical Localization of Nitric Oxide Synthase in the Autonomic Innervation of the Human Penis

1993 • 249 citations

Endothelium-Derived Nitric Oxide and Cyclooxygenase Products Modulate Corpus Cavernosum Smooth Muscle Tone

1992 • 226 citations

Nitric Oxide is a Potent Relaxant of Human and Rabbit Corpus Cavernosum

1992 • 202 citations

Immunohistochemical localization of peripheral nitric oxide synthase‐containing nerves using antibodies raised against synthesized C‐ and N‐terminal fragments of a cloned enzyme from rat brain

1993 • 195 citations

The effect of androgen on nitric oxide synthase in the male reproductive tract of the rat

1995 • 178 citations

Effects of the nitric oxide synthase inhibitor N^G‐nitro‐L‐arginine on the erectile response to cavernous nerve stimulation in the rabbit

1991 • 159 citations

Ultrastructural Changes in Impotent Penile Tissue: A Comparison of 65 Patients

1991 • 157 citations

Differential distribution of nitric oxide synthase in neural pathways to the urogenital organs (urethra, penis, urinary bladder) of the rat

1994 • 156 citations

Androgen Maintenance of Erectile Function in the Rat Penis1

1992 • 155 citations

Regeneration of Nitric Oxide Synthase-Containing Nerves After Cavernous Nerve Neurotomy in the Rat

1995 • 153 citations

Effect of aging on nitric oxide-mediated penile erection in rats

1995 • 130 citations

Nitric oxide and cGMP: mediators of pelvic nerve-stimulated erection in dogs

1993 • 118 citations

Characterization of inhibitory neurotransmission in the isolated corpus cavernosum from rabbit and man.

1992 • 118 citations

Biosynthesis of nitric oxide and citrulline from l-arginine by constitutive nitric oxide synthase present in rabbit corpus cavernosum

1992 • 117 citations

The effect of inhibitors of nitric oxide biosynthesis and cyclic GMP formation on nerve‐evoked relaxation of human cavernosal smooth muscle

1991 • 114 citations

Radiation-induced decrease in nitric oxide synthase--containing nerves in the rat penis.

1995 • 110 citations

Calcitonin gene-related peptide stimulates active Na(+)-K+ transport in rat soleus muscle

1993 • 99 citations

Nitric oxide gas: mediator, modulator, and pathophysiologic entity.

1992 • 88 citations

NANC neurotransmission in the bovine retractor penis muscle is blocked by superoxide anion following inhibition of superoxide dismutase with diethyldithiocarbamate

1994 • 81 citations

Characterization and localization of nitric oxide synthase in non‐adrenergic non‐cholinergic nerves from bovine retractor penis muscles

1992 • 77 citations

Basal and Acetylcholine-Stimulated Nitric Oxide Formation Mediates Relaxation of Rabbit Cavernous Smooth Muscle

1991 • 76 citations

Effects of N^G‐substituted analogues of <scp>l</scp>‐arginine on NANC relaxation of the rat anococcygeus and bovine retractor penis muscles and the bovine penile artery

1991 • 73 citations

Release of nitric oxide by nerve stimulation in the human urogenital tract

1994 • 69 citations

Nitric oxide mediates relaxation in rabbit and human corpus cavernosum smooth muscle

1992 • 66 citations

Nitric Oxide Mediates Penile Erection in Cats

1994 • 61 citations

Role of the nitric oxide donor linsidomine chlorhydrate (SIN-1) in the diagnosis and treatment of erectile dysfunction

1994 • 60 citations

Dihydrotestosterone is the active androgen in the maintenance of nitric oxide-mediated penile erection in the rat

1995 • 60 citations

Localization of Nitric Oxide Synthase in Spinal Nuclei Innervating Pelvic Ganglia

1995 • 52 citations

Expression of Inducible Nitric Oxide Synthase in Smooth Muscle Cells From Rat Penile Corpora Cavernosa

1995 • 47 citations

Intracellular mechanism of penile erection in monkeys

1994 • 47 citations

Inhibition of nerve stimulation-induced vasodilatation in corpora cavernosa of the pithed rat by blockade of nitric oxide synthase

1993 • 46 citations

Smooth Muscle Tone Regulation in Rabbit Cavernosal and Spongiosae Tissue by Cyclic AMP- and Cyclic GMP-Dependent Mechanisms

1994 • 43 citations

Co-localization of nitric oxide synthase and vasoactive intestinal peptide immunoreactivity in neurons of the major pelvic ganglion projecting to the rat rectum and penis

1994 • 43 citations

Coexistence of Nitric Oxide Synthase, Tyrosine Hydroxylase and Vasoactive Intestinal Polypeptide in Human Penile Tissue–a Triple Histochemical and Immunohistochemical Study

1995 • 43 citations

Endothelium Dependent Relaxation of Human Corpus Cavernosum by Bradykinin

1990 • 38 citations

Penile Erection in the Primate: Induction with Nitric-Oxide Donors

1994 • 38 citations

Nitric Oxide Relaxes Rabbit Corpus Cavernosum Smooth Muscle via a Potassium-Conductive Pathway

1996 • 31 citations

The effects of L‐arginine and N^G‐monomethyl L‐arginine on the inhibitory neurotransmission of the human corpus cavernosum penis

1990 • 20 citations

Intracavernous application of SIN-I in rabbit and man: functional and toxicological results.

1993 • 13 citations

The Effect of Vasoactive Intestinal Polypeptide (VIP) on Rabbit Cavernosal Smooth Muscle Contractility

1994 • 8 citations