Sphingolipids, apoptosis, cancer treatments and the ovary: investigating a crime against female fertility

BCL-2 family members and the mitochondria in apoptosis

1999 • 3,657 citations

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

1996 • 1,493 citations

Regulation of Ovarian Follicular Development in Primates: Facts and Hypotheses

1996 • 1,400 citations

Accelerated disappearance of ovarian follicles in mid-life: implications for forecasting menopause

1992 • 1,318 citations

A quantitative and cytological study of germ cells in human ovaries

1963 • 1,074 citations

REGULATION OF CERAMIDE PRODUCTION AND APOPTOSIS

1998 • 804 citations

Sphingosine 1-phosphate signalling in mammalian cells

2000 • 698 citations

Defects in regulation of apoptosis in caspase-2-deficient mice

1998 • 688 citations

Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine -1-phosphate therapy

2000 • 581 citations

Aromatic hydrocarbon receptor-driven Bax gene expression is required for premature ovarian failure caused by biohazardous environmental chemicals

2001 • 459 citations

Sphingosine 1-phosphate signalling in mammalian cells

2000 • 458 citations

Commuting the death sentence: how oocytes strive to survive

2001 • 383 citations

Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction

1997 • 354 citations

Targeting Ceramide Metabolism--a Strategy for Overcoming Drug Resistance

2001 • 317 citations

Functional Consequences of the Sustained or Transient Activation by Bax of the Mitochondrial Permeability Transition Pore

1999 • 295 citations

Radiation-induced apoptosis

2000 • 281 citations

Sphingosine‐1‐phosphate: signaling inside and out

2000 • 275 citations

Sphingosine 1-Phosphate Inhibits Activation of Caspases that Cleave Poly(ADP-ribose) Polymerase and Lamins during Fas- and Ceramide-mediated Apoptosis in Jurkat T Lymphocytes

1998 • 265 citations

Lysophosphatidic Acid and Sphingosine 1-Phosphate Protection of T Cells from Apoptosis in Association with Suppression of Bax

1999 • 219 citations

Preliminary Experience with Subcutaneous Human Ovarian Cortex Transplantation in the NOD-SCID Mouse1

1999 • 219 citations

Sphingosine enhances apoptosis of radiation-resistant prostate cancer cells.

2000 • 156 citations

Morphometric study of the human neonatal ovary

1991 • 151 citations

Sphingosine kinase: a mediator of vital cellular functions

2001 • 151 citations

Sphingosine 1-phosphate receptors

2001 • 139 citations

Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria

2001 • 139 citations

Sphingosine generation, cytochrome c release, and activation of caspase-7 in doxorubicin-induced apoptosis of MCF7 breast adenocarcinoma cells

2001 • 134 citations

The LPA receptors

2001 • 121 citations

Programmed Cell Death in the Ovary: Insights and Future Prospects Using Genetic Technologies

2001 • 103 citations

Molecular biology in reproductive medicine

1999 • 94 citations

Book Review: Molecular Biology in Reproductive Medicine

1999 • 72 citations

Subtype-specific, differential activities of the EDG family receptors for sphingosine-1-phosphate, a novel lysophospholipid mediator

2001 • 67 citations

Modulation of apoptotic pathways triggered by cytotoxic agents.

2002 • 30 citations

Cancer Obstetrics and Gynecology

2000 • 21 citations

Cancer obstetrics and gynecology

2015 • 10 citations