Lowering serum urate does not improve endothelial function in patients with type 2 diabetes

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2002 • 10,002 citations

Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus

1997 • 6,073 citations

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2007 • 2,487 citations

Serum Uric Acid and Cardiovascular Mortality

2000 • 1,497 citations

Prospective Evaluation of a Method for Estimating Ascending Aortic Pressure From the Radial Artery Pressure Waveform

2001 • 1,160 citations

Hyperuricemia induces endothelial dysfunction

2005 • 1,156 citations

Reproducibility of pulse wave velocity and augmentation index measured by pulse wave analysis

1998 • 920 citations

Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications

2003 • 888 citations

Uric Acid–Induced C-Reactive Protein Expression

2005 • 831 citations

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2003 • 814 citations

Predictive value of noninvasivelydetermined endothelial dysfunction for long-term cardiovascular events inpatients with peripheral vascular disease

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2005 • 629 citations

High-Dose Allopurinol Improves Endothelial Function by Profoundly Reducing Vascular Oxidative Stress and Not by Lowering Uric Acid

2006 • 570 citations

Effects of Xanthine Oxidase Inhibition With Allopurinol on Endothelial Function and Peripheral Blood Flow in Hyperuricemic Patients With Chronic Heart Failure

2002 • 559 citations

Prospective study of risk factors for development of non-insulin dependent diabetes in middle aged British men

1995 • 542 citations

Allopurinol Normalizes Endothelial Dysfunction in Type 2 Diabetics With Mild Hypertension

2000 • 475 citations

Serum Uric Acid Is a Strong Predictor of Stroke in Patients With Non–Insulin-Dependent Diabetes Mellitus

1998 • 419 citations

Evaluation of three devices for self-measurement of blood pressure according to the revised British Hypertension Society Protocol: the Omron HEM-705CP, Philips HP5332, and Nissei DS-175.

1996 • 415 citations

Measuring Forearm Blood Flow and Interpreting the Responses to Drugs and Mediators

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Protective role of endothelial nitric oxide synthase

2002 • 376 citations

Effect of Atorvastatin and Irbesartan, Alone and in Combination, on Postprandial Endothelial Dysfunction, Oxidative Stress, and Inflammation in Type 2 Diabetic Patients

2005 • 303 citations

Uric acid in chronic heart failure: a marker of chronic inflammation

1998 • 284 citations

Additive Beneficial Effects of Losartan Combined With Simvastatin in the Treatment of Hypercholesterolemic, Hypertensive Patients

2004 • 281 citations

Uric Acid and Endothelial Dysfunction in Essential Hypertension

2006 • 246 citations

Xanthine Oxidase Inhibition Reverses Endothelial Dysfunction in Heavy Smokers

2003 • 227 citations

Effect of hyperuricemia upon endothelial function in patients at increased cardiovascular risk

2004 • 224 citations

Preferential stiffening of central over peripheral arteries in type 2 diabetes

2003 • 165 citations

Serum Uric Acid

2006 • 152 citations

Endothelial Dysfunction and Low-Grade Inflammation Explain Much of the Excess Cardiovascular Mortality in Individuals With Type 2 Diabetes

2006 • 152 citations

Status of Endothelial Dependent Vasodilation in Patients With Hyperuricemia

2005 • 132 citations

Uric acid as a risk factor for cardiovascular disease

2000 • 127 citations

Aggressive Lipid Lowering Does Not Improve Endothelial Function in Type 2 Diabetes

2002 • 98 citations

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Endothelial Nitric Oxide Synthase

2005 • 88 citations

Physiologic Levels of Uric Acid Inhibit Xanthine Oxidase in Human Plasma

1993 • 83 citations

Advances in the management of malignancy-associated hyperuricaemia

1998 • 80 citations

Endothelial dysfunction and type 2 diabetes. Part 1: physiology and methods for exploring the endothelial function.

2001 • 75 citations

Glycaemic control in relation to xanthine oxidase and antioxidant indices in Malaysian Type 2 diabetes patients

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Estimation of ascending aortic pressure from radial arterial pressure using a generalised transfer function.

1996 • 63 citations

Binding of Xanthine Oxidase to Glycosaminoglycans Limits Inhibition by Oxypurinol

2004 • 62 citations

Effects of Acute Hyperglycemia on Endothelium-Dependent Vasodilation in Patients with Diabetes Mellitus or Impaired Glucose Metabolism

2003 • 59 citations

Reduced coronary NO production in conscious dogs after the development of alloxan-induced diabetes

1999 • 53 citations

Inhibition of xanthine oxidase by uric acid and its influence on superoxide radical production

1992 • 53 citations

Cardiovascular outcome of patients with abnormal coronary vasomotion and normal coronary arteriography is worse in type 2 diabetes mellitus than in arterial hypertension: A 10 year follow-up study

2005 • 43 citations

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2002 • 40 citations

Uric acid and the vasculature

2006 • 39 citations

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2006 • 37 citations

Impairment and restoration of nitric oxide-dependent vasodilation in cardiovascular disease

1997 • 36 citations

Endothelial dysfunction in Type 1 diabetes mellitus: relationship with LDL oxidation and the effects of vitamin E

1999 • 35 citations

Association of elevated serum uric acid with coronary heart disease in diabetes mellitus.

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Efficacy of urate oxidase (uricozyme) in tumour lysis induced urate nephropathy

1998 • 28 citations