The effect of macromolecular crowding on chaperonin-mediated protein folding

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Molecular chaperones in cellular protein folding

1996 • 3,540 citations

Macromolecular Crowding: Biochemical, Biophysical, and Physiological Consequences

1993 • 1,474 citations

The crystal structure of the bacterial chaperonln GroEL at 2.8 Å

1994 • 1,322 citations

Estimation of macromolecule concentrations and excluded volume effects for the cytoplasm of Escherichia coli

1991 • 1,253 citations

Range of Messenger Action of Calcium Ion and Inositol 1,4,5-Trisphosphate

1992 • 1,144 citations

Role of the Major Heat Shock Proteins as Molecular Chaperones

1993 • 1,096 citations

Chaperonin-mediated protein folding at the surface of groEL through a 'molten globule'-like intermediate

1991 • 853 citations

How crowded is the cytoplasm?

1982 • 807 citations

The effect of volume occupancy upon the thermodynamic activity of proteins: some biochemical consequences

1983 • 503 citations

Molecular chaperones: proteins essential for the biogenesis of some macromolecular structures

1989 • 491 citations

Dynamics of the Chaperonin ATPase Cycle: Implications for Facilitated Protein Folding

1994 • 461 citations

The crystal structure of the GroES co-chaperonin at 2.8 Å resolution

1996 • 436 citations

Mechanism of GroEL action: Productive release of polypeptide from a sequestered position under groes

1995 • 423 citations

Characterization of the Active Intermediate of a GroEL–GroES-Mediated Protein Folding Reaction

1996 • 403 citations

Hindered diffusion of inert tracer particles in the cytoplasm of mouse 3T3 cells.

1987 • 395 citations

Protein folding in the central cavity of the GroEL–GroES chaperonin complex

1996 • 373 citations

GroEL-mediated protein folding proceeds by multiple rounds of binding and release of nonnative forms

1994 • 359 citations

Location of a folding protein and shape changes in GroEL–GroES complexes imaged by cryo-electron microscopy

1994 • 334 citations

Protein folding in the cell: competing models of chaperonin function

1996 • 238 citations

Physical properties of cytoplasm

1994 • 210 citations

Mechanism of chaperonin action: GroES binding and release can drive GroEL-mediated protein folding in the absence of ATP hydrolysis.

1996 • 137 citations

Structure of the Heat Shock Protein Chaperonin-10 of Mycobacterium leprae

1996 • 135 citations

Refolding of Barnase in the Presence of GroE

1993 • 108 citations

Release of both native and non-native proteins from a cis-only GroEL ternary complex

1996 • 96 citations

Molecular chaperones in protein folding and translocation

1996 • 83 citations

Toward a mechanism for GroEL.GroES chaperone activity: an ATPase-gated and -pulsed folding and annealing cage.

1996 • 82 citations

Generation of a stable folding intermediate which can be rescued by the chaperonins GroEL and GroES

1994 • 73 citations

The folding of GroEL-bound barnase as a model for chaperonin-mediated protein folding.

1995 • 64 citations

GroEL, GroES, and ATP-dependent folding and spontaneous assembly of ornithine transcarbamylase.

1993 • 64 citations

THE NUCLEAR PERMEABILITY, INTRACELLULAR DISTRIBUTION, AND DIFFUSION OF INULIN IN THE AMPHIBIAN OOCYTE

1974 • 60 citations

Holobiochemistry: The effect of local environment upon the equilibria and rates of biochemical reactions

1990 • 57 citations

THE PERMEABILITY OF THE AMPHIBIAN OOCYTE NUCLEUS, IN SITU

1972 • 56 citations

Binding of defined regions of a polypeptide to GroEL and its implications for chaperonin-mediated protein folding

1995 • 52 citations

A highly efficient, cell-free translation/translocation system prepared fromXenopuseggs

1991 • 50 citations

Enhancement of recA protein-promoted DNA strand exchange activity by volume-occupying agents.

1992 • 44 citations

Morphogenesis and the Cytoskeleton: Studies of the Xenopus Embryo

1994 • 34 citations

Pass the Butter …

1996 • 33 citations