Detection of p53 tumor-suppressor-gene protein in bladder tumors and prostate cancer: possible clinical implications

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1992 • 3,092 citations

T antigen is bound to a host protein in SY40-transformed cells

1979 • 2,378 citations

The p53 proto-oncogene can act as a suppressor of transformation

1989 • 2,019 citations

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.

1988 • 1,140 citations

Identification of p53 Gene Mutations in Bladder Cancers and Urine Samples

1991 • 891 citations

Accumulation of p53 Tumor Suppressor Gene Protein: An Independent Marker of Prognosis in Breast Cancers

1992 • 757 citations

Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA) structural conservation and the detection of a nucleolar form

1990 • 736 citations

Nuclear Overexpression of p53 Protein in Transitional Cell Bladder Carcinoma: A Marker for Disease Progression

1993 • 544 citations

Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies.

1991 • 512 citations

Isolation of human‐p53‐specific monoclonal antibodies and their use in the studies of human p53 expression

1986 • 508 citations

Accumulation of p53 protein correlates with a poor prognosis in human lung cancer.

1992 • 384 citations

Membrane fusion machinery: Insights from synaptic proteins

1993 • 380 citations

Allelic losses of chromosomes 9, 11, and 17 in human bladder cancer.

1990 • 327 citations

Small Subgroup of Aggressive, Highly Proliferative Prostatic Carcinomas Defined by p53 Accumulation

1992 • 317 citations

Activating Mutations for Transformation by p53 Produce a Gene Product That Forms an hsc70-p53 Complex with an Altered Half-Life

1988 • 298 citations

Allelic loss of chromosome 17p distinguishes high grade from low grade transitional cell carcinomas of the bladder.

1990 • 252 citations

Molecular genetic alterations in superficial and locally advanced human bladder cancer.

1991 • 233 citations

Prognostic significance of p53 overexpression in gastric and colorectal carcinoma

1992 • 231 citations

Expression of mutant p53, c-erbB-2 and the epidermal growth factor receptor in transitional cell carcinoma of the human urinary bladder

1991 • 181 citations

Mutant p53, EGF receptor and c-erbB-2 expression in human breast cancer.

1991 • 92 citations

Molecular genetics of colorectal carcinoma

1992 • 85 citations

The Mspl polymorphism in intron 6 ofp53(TP53) detected by digestion of PCR products

1991 • 73 citations

Molecular markers for the diagnosis and prognosis of lung cancer

1992 • 54 citations

P53 accumulation in precursor lesions and early stages of bladder cancer

1994 • 47 citations

p53 Expression in Human Breast Cancer

1992 • 46 citations

Biallelic Apal polymorphism of the human p53 gene (TP53)

1991 • 38 citations

Abnormalities in p53 and DNA content in transitional cell carcinoma of the bladder

1994 • 23 citations

Detection of loss of heterozygosity in tumor DNA samples by PCR.

1991 • 19 citations

Das P53-Tumorsuppressorgen: Möglicher Prognosefaktor für den klinischen Verlauf von Harnblasenkarzinomen?

1993 • 1 citations