Catalysis and Function of the p38α·MK2a Signaling Complex

ROLE OF CYTOKINES IN RHEUMATOID ARTHRITIS

1996 • 2,527 citations

Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site

2002 • 818 citations

MAPKAP kinase 2 is essential for LPS-induced TNF-α biosynthesis

1999 • 744 citations

Activating transcription factor 4

2007 • 505 citations

MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay

2004 • 488 citations

MAPKAP kinase-2; a novel protein kinase activated by mitogen-activated protein kinase.

1992 • 486 citations

Mitogen-Activated Protein Kinase p38 Controls the Expression and Posttranslational Modification of Tristetraprolin, a Regulator of Tumor Necrosis Factor Alpha mRNA Stability

2001 • 449 citations

p38 Mitogen-Activated Protein Kinase Inhibitors— Mechanisms and Therapeutic Potentials

1999 • 348 citations

Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2

1998 • 336 citations

Crystal Structures of MAP Kinase p38 Complexed to the Docking Sites on Its Nuclear Substrate MEF2A and Activator MKK3b

2002 • 309 citations

Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions

2001 • 278 citations

Leptomycin B-sensitive nuclear export of MAPKAP kinase 2is regulated by phosphorylation

1998 • 270 citations

Genetic Dissection of the Cellular Pathways and Signaling Mechanisms in Modeled Tumor Necrosis Factor–induced Crohn's-like Inflammatory Bowel Disease

2002 • 264 citations

THE THERAPEUTIC EFFECTS OF AN ENGINEERED HUMAN ANTI-TUMOUR NECROSIS FACTOR ALPHA ANTIBODY (CDP571) IN RHEUMATOID ARTHRITIS

1995 • 234 citations

The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2

1993 • 196 citations

Identification of novel phosphorylation sites required for activation of MAPKAP kinase-2.

1995 • 187 citations

In the Cellular Garden of Forking Paths: How p38 MAPKs Signal for Downstream Assistance

2002 • 155 citations

Abnormal Migration Phenotype of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2−/− Neutrophils in Zigmond Chambers Containing Formyl-Methionyl-Leucyl-Phenylalanine Gradients

2001 • 74 citations

Inhibitors of p38 mitogen-activated protein kinase for the treatment of rheumatoid arthritis.

2003 • 62 citations

The Primary Structure of a Human Map Kinase Activated Protein Kinase 2

1994 • 56 citations

Identification of Two Distinct Regions of p38 MAPK Required for Substrate Binding and Phosphorylation

1999 • 32 citations

p38 Map Kinase Substrate Specificity Differs Greatly for Protein and Peptide Substrates

2000 • 31 citations